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Protein

Homeobox protein ceh-24

Gene

ceh-24

Organism
Caenorhabditis briggsae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi144 – 203HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein ceh-24
Gene namesi
Name:ceh-24
ORF Names:CBG11477
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componentsi: Chromosome V, Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG11477; CBP37592; WBGene00032588; Cbr-ceh-24.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000489941 – 293Homeobox protein ceh-24Add BLAST293

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG11477.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi215 – 245Asp-richAdd BLAST31

Sequence similaritiesi

Belongs to the NK-2 homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
HOGENOMiHOG000112912.
InParanoidiO17319.
OMAiSAINHQF.
OrthoDBiEOG091G0LZ2.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17319-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKESPSPQ HKKDEVVDDT EQETKDSEDD ATKKMKIKEG SKFTMNSILS
60 70 80 90 100
PLESLARVQQ QLLKMAAAQS GFGGNGSGGN GANGFPYPAR FATNCFSGPF
110 120 130 140 150
PGYNGSQNWY NGNDARFAAA AALLPCAIDP VRSAINHQFS MSQRRKRRVL
160 170 180 190 200
FSQAQVYELE RRFKQAKYLT APEREQLANS IRLTPTQVKI WFQNHRYKCK
210 220 230 240 250
RQEKEKAMSG LGHGDDGCSP PPGDDDDDDD KYSIEMDDKD DEEEDGAKPM
260 270 280 290
LKSNGVFGLP YPSPANAAAA AAAAAFNFQF GAQGPNPAYF MRW
Length:293
Mass (Da):32,371
Last modified:November 24, 2009 - v3
Checksum:iCC400756675C3A0A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti107Q → QG in AAB86603 (PubMed:9425137).Curated1
Sequence conflicti134A → R in AAB86603 (PubMed:9425137).Curated1
Sequence conflicti218C → S in AAB86603 (PubMed:9425137).Curated1
Sequence conflicti258G → GNFQ in AAB86603 (PubMed:9425137).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF026057 Genomic DNA. Translation: AAB86603.1.
HE600908 Genomic DNA. Translation: CAP30490.3.

Genome annotation databases

EnsemblMetazoaiCBG11477; CBG11477; WBGene00032588.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF026057 Genomic DNA. Translation: AAB86603.1.
HE600908 Genomic DNA. Translation: CAP30490.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6238.CBG11477.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG11477; CBG11477; WBGene00032588.

Organism-specific databases

WormBaseiCBG11477; CBP37592; WBGene00032588; Cbr-ceh-24.

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
HOGENOMiHOG000112912.
InParanoidiO17319.
OMAiSAINHQF.
OrthoDBiEOG091G0LZ2.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHM24_CAEBR
AccessioniPrimary (citable) accession number: O17319
Secondary accession number(s): A8XCX2, Q61FW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: November 24, 2009
Last modified: September 7, 2016
This is version 83 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.