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Protein

Calcium-transporting ATPase

Gene

SERCA

Organism
Procambarus clarkii (Red swamp crayfish)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + H2O + Ca2+(Side 1) = ADP + phosphate + Ca2+(Side 2).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processCalcium transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotationSAAS annotation, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Calcium-transporting ATPaseUniRule annotation (EC:3.6.3.8UniRule annotation)
Gene namesi
Name:SERCAImported
OrganismiProcambarus clarkii (Red swamp crayfish)Imported
Taxonomic identifieri6728 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAstacideaAstacoideaCambaridaeProcambarus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei57 – 76HelicalUniRule annotationAdd BLAST20
Transmembranei88 – 107HelicalUniRule annotationAdd BLAST20
Transmembranei292 – 321HelicalUniRule annotationAdd BLAST30
Transmembranei760 – 781HelicalUniRule annotationAdd BLAST22
Transmembranei833 – 857HelicalUniRule annotationAdd BLAST25
Transmembranei928 – 950HelicalUniRule annotationAdd BLAST23
Transmembranei956 – 980HelicalUniRule annotationAdd BLAST25
Transmembranei1001 – 1019HelicalUniRule annotationAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiO17314

Structurei

3D structure databases

ProteinModelPortaliO17314
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 77Cation_ATPase_NInterPro annotationAdd BLAST75

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.40.1110.101 hit
3.40.50.10002 hits
InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR005782 P-type_ATPase_IIA
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
PF00690 Cation_ATPase_N, 1 hit
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01116 ATPase-IIA1_Ca, 1 hit
TIGR01494 ATPase_P-type, 3 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

O17314-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDAHCFPVE DVVAKFGVNI ENGLSASQVK DYQAKYGPNE LPAEEGKSLL
60 70 80 90 100
QLILEQFYDL LVKILLLAAI ISFVLACFEE GEETVTAFVE PFVILLILIA
110 120 130 140 150
NAIVGVWQER NAESAIEALK EYEPEMGKVV RSNKHGVQKV RAREIVPGDI
160 170 180 190 200
VEVSVGDKIP ADIRLVKIFS TTLRIDQSIL TGESVSVIKH ADAIPDPKAV
210 220 230 240 250
NQDKKNILFS GTNVSAGKAR GVVIGTGLAT AIGKIRTQMA ETEEIKTPLQ
260 270 280 290 300
QKLDEFGEQL SKVISIICVA VWAINIGHFN DPAHGGSWIK GAIYYFKIAV
310 320 330 340 350
ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS
360 370 380 390 400
DKTGTLTTNQ MSVSRMFIMD KVEGNDSSLL EFEVTGSTYE PIGDVYLKNT
410 420 430 440 450
KVKGSDFEGL QELSTISFMC NDSSIDFNEF KNVFEKVGEA TETALIVLGE
460 470 480 490 500
KINPYNMSKS GLDRRSAAII ARHDMETKWK KEFTLEFSRD RKSMSSYCVP
510 520 530 540 550
LKPTRLGTGP KMFCKGAPEG VLDRCTHVRV GTQKVPLTAG VKEKILSVTR
560 570 580 590 600
DYGCGRDTLR CLGLATIDNP MKPEDMDLGE ASKFYTYEVN MTFVGVVGML
610 620 630 640 650
DPPRKEVKDS IQRCRDAGIR VIVITGDNKA TAEAICRRIG VFKEDEDTTG
660 670 680 690 700
MSYSGREFDE LSPEEQRQAC IRSRLFSRVE PFRKSKIVEY LQGENEISAM
710 720 730 740 750
TGDGVNDAPA LKKAEIGIAM GSGTAVAKSA SEMVLADDNF SSIVAAVEEG
760 770 780 790 800
RAIYNNMKQF IRYLISSNVG EVVSIFLTAA LGLPEALIPV QLLWVNLVTD
810 820 830 840 850
GLPATALGFN PPDLDIMDKP PRRADESLIS GWLFFRYMAI GGYVGAATVF
860 870 880 890 900
AASWWFMYDP TGPHLNYYQL SHHLQCLGDP ENFEGLDCNI FSHPAPMTMA
910 920 930 940 950
LSVLVTIEML NALNSLSENQ SLLIMPPWVN FWLLAAMALS MTLHFIILYI
960 970 980 990 1000
DILSTVFQVM PLSVAQWVAV LKISFPVLLL DETLKFIARN YTDGENNLYK
1010 1020
CHWIVLAWAT YFAYIKIYFF
Length:1,020
Mass (Da):112,493
Last modified:January 1, 1998 - v1
Checksum:i0D0E870229A78601
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF025848 mRNA Translation: AAB82290.1

Similar proteinsi

Entry informationi

Entry nameiO17314_PROCL
AccessioniPrimary (citable) accession number: O17314
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)