Unreviewed, UniProtKB/TrEMBL O17311 (O17311_DROME)

Names and origin

Protein names

Submitted name:
    20S proteasome beta2 subunit EMBL AAB82570.1

Gene names

Name:	Prosbeta2 FlyBase FBgn0023174
Synonyms:	Pros-beta-2 FlyBase FBgn0023174, beta2_dm EMBL AAB82570.1
ORF Names:	CG3329 FlyBase FBgn0023174

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAB82570.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	Cleavage of peptide bonds with very broad specificity. Spearmint SPM016050
Sequence similarities	Belongs to the peptidase T1B family. RuleBase RU004202V0

Ontologies

Keywords
Cellular component	Cytoplasm Spearmint SPM016050 Nucleus Spearmint SPM016050 Proteasome Spearmint SPM016050
Molecular function	Hydrolase Protease Threonine protease Spearmint SPM016050
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytosol Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell proteasome core complex Inferred from electronic annotation. Source: InterPro
Molecular function	threonine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O17311-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 2BFF408CB2DC91F2	FASTA	272	29,895
	10 20 30 40 50 60 MDLDNARELP RAGFNFDNCK RNATLLNRGF KPPITTKTGT TIVGIIYKDG VILGADTRAT 70 80 90 100 110 120 EGPIVSDKNC AKIHYLAKNI YCCGAGTAAD TEMTTDLISS QLELHRLQTD REVRVVAANT 130 140 150 160 170 180 MLKQMLFRYQ GHISAALVLG GVDKTGPHIY SIHPHGSSDK LPYATMGSGS LAAMTVFESR 190 200 210 220 230 240 WKPDLSEEEG KKLVRDADPT GVFNDLGSGS NIDLCVIRKG SVEYLRNYEL ANKKGKRQLD 250 260 270 YRFKTGTSTV LHTNIKDLLV TERVQAVPME IS

References

[1]	"The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit." Smyth K.A., Belote J.M. Genetics 151:211-220(1999) [PubMed: 9872961] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF025791 mRNA. Translation: AAB82570.1.
3D structure databases
HSSP	HSSP built from PDB template 1RYP based on UniProtKB P25043.
ModBase	Search...
Protein family/group databases
MEROPS	T01.011.
Proteomic databases
PRIDE	O17311.
Genome annotation databases
Ensembl	FBgn0023174. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0023174. Prosbeta2.
Phylogenomic databases
HOGENOM	O17311.
Gene expression databases
ArrayExpress	O17311.
Family and domain databases
InterPro	IPR000243. Pept_T1A_subB. IPR001353. Proteasome_alpha_beta_su. IPR016050. Proteasome_bsu_CS. [Graphical view]
Pfam	PF00227. Proteasome. 1 hit. [Graphical view]
PRINTS	PR00141. PROTEASOME.
PROSITE	PS00854. PROTEASOME_B. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O17311_DROME

Accession

Primary (citable) accession number: O17311

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	July 7, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)