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Protein
Submitted name:

Mesodermal Lineage Specification

Gene

mls-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • muscle cell fate specification Source: WormBase
  • post-embryonic development Source: WormBase
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mesodermal Lineage SpecificationImported
Gene namesi
Name:mls-1Imported
ORF Names:CELE_H14A12.4Imported, H14A12.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiH14A12.4; CE11584; WBGene00003376; mls-1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

  • nucleus Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO17212.

Interactioni

Protein-protein interaction databases

STRINGi6239.H14A12.4.

Structurei

3D structure databases

ProteinModelPortaliO17212.
SMRiO17212. Positions 31-209.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains T-box DNA-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG3586. Eukaryota.
ENOG410Y98J. LUCA.
GeneTreeiENSGT00760000118897.
HOGENOMiHOG000286000.
InParanoidiO17212.
OMAiRQVISFQ.
OrthoDBiEOG7GN2PM.
PhylomeDBiO17212.

Family and domain databases

Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17212-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRNFSIDAI LARKPVEKRK QIITKDNCKF IRVFLQSSNL WRRFHNLGTE
60 70 80 90 100
MIVTKSGRRM FPTLSVIIAG LDPVKSYVVM VDLECIEMKR FRYSFHQSKW
110 120 130 140 150
ISTGPGESEL PSRMFVHTDS PARGAHWMRA PVSFDKMKLT NNQLDNNGHI
160 170 180 190 200
IVNSMHKYRP RVHIIEQDDS QKRHTFSFEE TEFIAVTAYQ NHRITSLKIE
210 220 230 240 250
SNPFAKGFRE CEVQGIEMNS VGGMTGGPAF QSVFPLIFPY FANLASNMNV

NK
Length:252
Mass (Da):29,067
Last modified:January 1, 1998 - v1
Checksum:i0DFDB0A9F4F9B130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD72344.1.
PIRiA88508.
RefSeqiNP_498640.1. NM_066239.3.
UniGeneiCel.10354.

Genome annotation databases

EnsemblMetazoaiH14A12.4; H14A12.4; WBGene00003376.
GeneIDi186741.
KEGGicel:CELE_H14A12.4.
UCSCiH14A12.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD72344.1.
PIRiA88508.
RefSeqiNP_498640.1. NM_066239.3.
UniGeneiCel.10354.

3D structure databases

ProteinModelPortaliO17212.
SMRiO17212. Positions 31-209.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.H14A12.4.

Proteomic databases

PaxDbiO17212.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiH14A12.4; H14A12.4; WBGene00003376.
GeneIDi186741.
KEGGicel:CELE_H14A12.4.
UCSCiH14A12.4. c. elegans.

Organism-specific databases

CTDi186741.
WormBaseiH14A12.4; CE11584; WBGene00003376; mls-1.

Phylogenomic databases

eggNOGiKOG3586. Eukaryota.
ENOG410Y98J. LUCA.
GeneTreeiENSGT00760000118897.
HOGENOMiHOG000286000.
InParanoidiO17212.
OMAiRQVISFQ.
OrthoDBiEOG7GN2PM.
PhylomeDBiO17212.

Family and domain databases

Gene3Di2.60.40.820. 1 hit.
InterProiIPR008967. p53-like_TF_DNA-bd.
IPR001699. TF_T-box.
IPR018186. TF_T-box_CS.
[Graphical view]
PANTHERiPTHR11267. PTHR11267. 1 hit.
PfamiPF00907. T-box. 1 hit.
[Graphical view]
PRINTSiPR00937. TBOX.
SMARTiSM00425. TBOX. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
PROSITEiPS01283. TBOX_1. 1 hit.
PS50252. TBOX_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO17212_CAEEL
AccessioniPrimary (citable) accession number: O17212
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.