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Protein

Major sperm protein

Gene

CELE_F42G2.5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.UniRule annotation

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiREACT_183003. Sphingolipid de novo biosynthesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Major sperm proteinUniRule annotation
Gene namesi
ORF Names:CELE_F42G2.5Imported, F42G2.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiF42G2.5; CE10314; WBGene00018354.

Subcellular locationi

GO - Cellular componenti

  1. cytoskeleton Source: UniProtKB-KW
  2. endoplasmic reticulum membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiO17099.
PRIDEiO17099.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
rrc-1Q204985EBI-2316398,EBI-2316401

Protein-protein interaction databases

IntActiO17099. 1 interaction.
STRINGi6239.F42G2.5.

Structurei

3D structure databases

ProteinModelPortaliO17099.
SMRiO17099. Positions 8-122, 132-199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Zinc-fingerUniRule annotation

Phylogenomic databases

eggNOGiCOG5066.
GeneTreeiENSGT00530000064633.
HOGENOMiHOG000113967.
InParanoidiO17099.
OrthoDBiEOG7CK389.
PhylomeDBiO17099.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17099-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEKKSLLEV PPELVFSGPF DHVITTYMTL TNISQSPVCF LVKTTVPNSY
60 70 80 90 100
CVRPNRGILN IGDSKQIEVM LQPLEKVPPD AKQHKFLVQS CVAPSIDVSD
110 120 130 140 150
LESVWKNVKP DELTYNRLVV TFVDNTDSKS NIECEICTLE FSSVVDNQIP
160 170 180 190 200
RILQCGHSIC QSCASKLAKN CVILCPFCRN ETNVSSVASL PKNFALLQAI
210 220 230 240 250
DQKTLRVPPL EIAKLRQQLS CQLSKLEEQV SKTDKSIKAV GRAQLSNLKD
260 270 280 290 300
GREFQERKDS IVSYYASIRE TINALENEAI GKLHTIADMN VSKNALLVAE
310 320 330 340 350
LSEILKHQNL KIAELKLSME MDDVELATRS LTDSGTECAV VKPAVLDVAL
360 370
TFPEIDKMAL LSMTTKFPSN FSTV
Length:374
Mass (Da):41,505
Last modified:January 1, 1998 - v1
Checksum:i8277E0E27327A8C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081261 Genomic DNA. Translation: CCD70285.1.
PIRiT32286.
RefSeqiNP_494271.1. NM_061870.1.
UniGeneiCel.15141.

Genome annotation databases

EnsemblMetazoaiF42G2.5; F42G2.5; WBGene00018354.
GeneIDi185673.
KEGGicel:CELE_F42G2.5.
UCSCiF42G2.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081261 Genomic DNA. Translation: CCD70285.1.
PIRiT32286.
RefSeqiNP_494271.1. NM_061870.1.
UniGeneiCel.15141.

3D structure databases

ProteinModelPortaliO17099.
SMRiO17099. Positions 8-122, 132-199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO17099. 1 interaction.
STRINGi6239.F42G2.5.

Proteomic databases

PaxDbiO17099.
PRIDEiO17099.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF42G2.5; F42G2.5; WBGene00018354.
GeneIDi185673.
KEGGicel:CELE_F42G2.5.
UCSCiF42G2.5. c. elegans.

Organism-specific databases

CTDi185673.
WormBaseiF42G2.5; CE10314; WBGene00018354.

Phylogenomic databases

eggNOGiCOG5066.
GeneTreeiENSGT00530000064633.
HOGENOMiHOG000113967.
InParanoidiO17099.
OrthoDBiEOG7CK389.
PhylomeDBiO17099.

Enzyme and pathway databases

ReactomeiREACT_183003. Sphingolipid de novo biosynthesis.

Miscellaneous databases

NextBioi929088.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO17099_CAEEL
AccessioniPrimary (citable) accession number: O17099
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: March 4, 2015
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.