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Protein

Major sperm protein

Gene

CELE_F42G2.5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.UniRule annotation

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-CEL-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Recommended name:
Major sperm proteinUniRule annotation
Gene namesi
ORF Names:CELE_F42G2.5Imported, F42G2.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF42G2.5; CE10314; WBGene00018354.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiO17099.
PeptideAtlasiO17099.

Expressioni

Gene expression databases

BgeeiWBGene00018354.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
rrc-1Q204985EBI-2316398,EBI-2316401

Protein-protein interaction databases

IntActiO17099. 1 interactor.
STRINGi6239.F42G2.5.

Structurei

3D structure databases

ProteinModelPortaliO17099.
SMRiO17099.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 123MSPInterPro annotationAdd BLAST123
Domaini134 – 179RING-typeInterPro annotationAdd BLAST46

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0439. Eukaryota.
KOG4185. Eukaryota.
COG5066. LUCA.
GeneTreeiENSGT00390000006947.
HOGENOMiHOG000113967.
InParanoidiO17099.
OrthoDBiEOG091G0KJ2.
PhylomeDBiO17099.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR013783. Ig-like_fold.
IPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PANTHERiPTHR10809. PTHR10809. 1 hit.
PfamiView protein in Pfam
PF00635. Motile_Sperm. 1 hit.
PF13639. zf-RING_2. 1 hit.
SMARTiView protein in SMART
SM00184. RING. 1 hit.
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiView protein in PROSITE
PS50202. MSP. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O17099-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEKKSLLEV PPELVFSGPF DHVITTYMTL TNISQSPVCF LVKTTVPNSY
60 70 80 90 100
CVRPNRGILN IGDSKQIEVM LQPLEKVPPD AKQHKFLVQS CVAPSIDVSD
110 120 130 140 150
LESVWKNVKP DELTYNRLVV TFVDNTDSKS NIECEICTLE FSSVVDNQIP
160 170 180 190 200
RILQCGHSIC QSCASKLAKN CVILCPFCRN ETNVSSVASL PKNFALLQAI
210 220 230 240 250
DQKTLRVPPL EIAKLRQQLS CQLSKLEEQV SKTDKSIKAV GRAQLSNLKD
260 270 280 290 300
GREFQERKDS IVSYYASIRE TINALENEAI GKLHTIADMN VSKNALLVAE
310 320 330 340 350
LSEILKHQNL KIAELKLSME MDDVELATRS LTDSGTECAV VKPAVLDVAL
360 370
TFPEIDKMAL LSMTTKFPSN FSTV
Length:374
Mass (Da):41,505
Last modified:January 1, 1998 - v1
Checksum:i8277E0E27327A8C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD70285.1.
PIRiT32286.
RefSeqiNP_494271.1. NM_061870.1.
UniGeneiCel.15141.

Genome annotation databases

EnsemblMetazoaiF42G2.5; F42G2.5; WBGene00018354.
GeneIDi185673.
KEGGicel:CELE_F42G2.5.
UCSCiF42G2.5. c. elegans.

Entry informationi

Entry nameiO17099_CAEEL
AccessioniPrimary (citable) accession number: O17099
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: August 30, 2017
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported