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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-251

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-251Imported
ORF Names:CELE_ZK488.4Imported, ZK488.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiZK488.4; CE15357; WBGene00022756; nhr-251.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO17020.

Interactioni

Protein-protein interaction databases

DIPiDIP-26398N.
IntActiO17020. 1 interaction.
MINTiMINT-1065646.
STRINGi6239.ZK488.4.

Structurei

3D structure databases

ProteinModelPortaliO17020.
SMRiO17020. Positions 2-127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5555Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17020.
PhylomeDBiO17020.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17020-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACASFFRRT VSFGIRFLCK EGNRCPISQE IRFFCRSCRY DKCISVGMNR
60 70 80 90 100
GQVQQKRDDN NVPKYVLDSR RLGIQEIVRG YTTSRTVPSE PAEPISPGST
110 120 130 140 150
GSTGSTRSSS PETSPAEPSK KSEFSIILNT YPDDLLQYYV KQVEMSMIHK
160 170 180 190 200
QLGLLKNTLL VKSVDELVDI SETLNDLSME ACMNCPGVDI LRQRDVEVIL
210 220 230 240 250
KSFHFANVWM DSIWAYSRHN ESIVNKFFEN NGPLSMFINQ IKSTLGSSLS
260 270 280 290 300
QLTFNIYEFS ALKAFCVWKL SYHDSTISIN IMAEEQYIGI CSALRKHYEA
310 320 330 340
TTNMTDVDIA MRIAEITLQI VPATTIYQDM IRFYQQNGLI DNL
Length:343
Mass (Da):39,024
Last modified:January 1, 1998 - v1
Checksum:i22C3923E199FE0B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71523.1.
PIRiT32232.
RefSeqiNP_503258.1. NM_070857.1.
UniGeneiCel.1291.

Genome annotation databases

EnsemblMetazoaiZK488.4; ZK488.4; WBGene00022756.
GeneIDi191329.
KEGGicel:CELE_ZK488.4.
UCSCiZK488.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71523.1.
PIRiT32232.
RefSeqiNP_503258.1. NM_070857.1.
UniGeneiCel.1291.

3D structure databases

ProteinModelPortaliO17020.
SMRiO17020. Positions 2-127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26398N.
IntActiO17020. 1 interaction.
MINTiMINT-1065646.
STRINGi6239.ZK488.4.

Proteomic databases

PaxDbiO17020.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK488.4; ZK488.4; WBGene00022756.
GeneIDi191329.
KEGGicel:CELE_ZK488.4.
UCSCiZK488.4. c. elegans.

Organism-specific databases

CTDi191329.
WormBaseiZK488.4; CE15357; WBGene00022756; nhr-251.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17020.
PhylomeDBiO17020.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO17020_CAEEL
AccessioniPrimary (citable) accession number: O17020
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.