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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-251

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 55Nuclear receptorPROSITE-ProRule annotationAdd BLAST55

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-251Imported
ORF Names:CELE_ZK488.4Imported, ZK488.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiZK488.4 ; CE15357 ; WBGene00022756 ; nhr-251

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO17020

Expressioni

Gene expression databases

BgeeiWBGene00022756

Interactioni

Protein-protein interaction databases

DIPiDIP-26398N
IntActiO17020, 1 interactor
STRINGi6239.ZK488.4

Structurei

3D structure databases

ProteinModelPortaliO17020
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 55Nuclear receptorInterPro annotationAdd BLAST55
Domaini131 – 343NR LBDInterPro annotationAdd BLAST213

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00390000015766
HOGENOMiHOG000016336
InParanoidiO17020
OrthoDBiEOG091G0NZ5
PhylomeDBiO17020

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00105 zf-C4, 1 hit
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O17020-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACASFFRRT VSFGIRFLCK EGNRCPISQE IRFFCRSCRY DKCISVGMNR
60 70 80 90 100
GQVQQKRDDN NVPKYVLDSR RLGIQEIVRG YTTSRTVPSE PAEPISPGST
110 120 130 140 150
GSTGSTRSSS PETSPAEPSK KSEFSIILNT YPDDLLQYYV KQVEMSMIHK
160 170 180 190 200
QLGLLKNTLL VKSVDELVDI SETLNDLSME ACMNCPGVDI LRQRDVEVIL
210 220 230 240 250
KSFHFANVWM DSIWAYSRHN ESIVNKFFEN NGPLSMFINQ IKSTLGSSLS
260 270 280 290 300
QLTFNIYEFS ALKAFCVWKL SYHDSTISIN IMAEEQYIGI CSALRKHYEA
310 320 330 340
TTNMTDVDIA MRIAEITLQI VPATTIYQDM IRFYQQNGLI DNL
Length:343
Mass (Da):39,024
Last modified:January 1, 1998 - v1
Checksum:i22C3923E199FE0B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD71523.1
PIRiT32232
RefSeqiNP_503258.1, NM_070857.1
UniGeneiCel.1291

Genome annotation databases

EnsemblMetazoaiZK488.4; ZK488.4; WBGene00022756
GeneIDi191329
KEGGicel:CELE_ZK488.4
UCSCiZK488.4 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO17020_CAEEL
AccessioniPrimary (citable) accession number: O17020
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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