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Protein
Submitted name:

Nuclear Hormone Receptor family

Gene

nhr-270

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear Hormone Receptor familyImported
Gene namesi
Name:nhr-270Imported
ORF Names:CELE_R13D11.8Imported, R13D11.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiR13D11.8a; CE39955; WBGene00020062; nhr-270.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiO17013.
PRIDEiO17013.

Interactioni

Protein-protein interaction databases

IntActiO17013. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliO17013.
SMRiO17013. Positions 70-398.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 14276Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000017606.
InParanoidiO17013.
OMAiCGDQVKS.
OrthoDBiEOG77T18K.
PhylomeDBiO17013.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17013-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYEFAGGPY RPLCPLSKIS RRWNLNSRGG AIVPSSTSVH SLGHSISMLA
60 70 80 90 100
VMSPSTSKAP NLIAILTERC AVCGDQVKSD RLGCPACLGC ILFFRRSVLK
110 120 130 140 150
NASYKCGRKG ACPVVSEFRS TCRHCRFKKC FDVGMKASAV NTCIANPSPP
160 170 180 190 200
PYVDVPKDLL GPCVILQTRQ IEEHKEQSVK HVRRASASDV NKMLMWSFND
210 220 230 240 250
AVEWASDYEP FQLLPNELQK CVISEFGVAF FLIDQGFKSA RESKRGFWMF
260 270 280 290 300
QNGTFLHFDY FHGLANIDDT ADREKTKHHC EFVQYLEVTI KQQFQLLQID
310 320 330 340 350
EFELAAIKTL LLLSCSYPKP EIFAEFKGTM QKLKNKCFAE LMSYLTVKLP
360 370 380 390
ATHAERFGKL ILVMGEIRAA VKVLYNHTKV SDLFDPSKFN MFVRSFLLT
Length:399
Mass (Da):45,079
Last modified:April 4, 2006 - v2
Checksum:i9CC2D99FDAB4176A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71087.1.
PIRiG88941.
RefSeqiNP_503328.2. NM_070927.5.
UniGeneiCel.27492.

Genome annotation databases

EnsemblMetazoaiR13D11.8; R13D11.8; WBGene00020062.
R13D11.8a; R13D11.8a; WBGene00020062.
GeneIDi187867.
KEGGicel:CELE_R13D11.8.
UCSCiR13D11.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71087.1.
PIRiG88941.
RefSeqiNP_503328.2. NM_070927.5.
UniGeneiCel.27492.

3D structure databases

ProteinModelPortaliO17013.
SMRiO17013. Positions 70-398.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO17013. 1 interaction.

Proteomic databases

PaxDbiO17013.
PRIDEiO17013.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiR13D11.8; R13D11.8; WBGene00020062.
R13D11.8a; R13D11.8a; WBGene00020062.
GeneIDi187867.
KEGGicel:CELE_R13D11.8.
UCSCiR13D11.8. c. elegans.

Organism-specific databases

CTDi187867.
WormBaseiR13D11.8a; CE39955; WBGene00020062; nhr-270.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000017606.
InParanoidiO17013.
OMAiCGDQVKS.
OrthoDBiEOG77T18K.
PhylomeDBiO17013.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO17013_CAEEL
AccessioniPrimary (citable) accession number: O17013
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: April 4, 2006
Last modified: July 6, 2016
This is version 129 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.