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Protein
Submitted name:

SyNapTotagmin

Gene

snt-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-8856825. Cargo recognition for clathrin-mediated endocytosis.
R-CEL-8856828. Clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Submitted name:
SyNapTotagminImported
Gene namesi
Name:snt-5Imported
ORF Names:CELE_R12A1.2Imported, R12A1.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiR12A1.2a; CE29448; WBGene00004925; snt-5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 29HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO16700.

Expressioni

Gene expression databases

BgeeiWBGene00004925.
ExpressionAtlasiO16700. differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiO16700. 1 interactor.
STRINGi6239.R12A1.2.2.

Structurei

3D structure databases

ProteinModelPortaliO16700.
SMRiO16700.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini185 – 271C2InterPro annotationAdd BLAST87
Domaini315 – 404C2InterPro annotationAdd BLAST90

Sequence similaritiesi

Contains 2 C2 domains.UniRule annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IT36. Eukaryota.
ENOG410YFCM. LUCA.
GeneTreeiENSGT00760000118973.
InParanoidiO16700.
OMAiFIHRVLM.
OrthoDBiEOG091G0XMQ.
PhylomeDBiO16700.

Family and domain databases

Gene3Di2.60.40.150. 2 hits.
InterProiIPR000008. C2_dom.
IPR001565. Synaptotagmin.
[Graphical view]
PfamiPF00168. C2. 2 hits.
[Graphical view]
PRINTSiPR00360. C2DOMAIN.
PR00399. SYNAPTOTAGMN.
SMARTiSM00239. C2. 2 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 2 hits.
PROSITEiPS50004. C2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O16700-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEWWWWVLV AILSLCAVIL SSCALYFGAR ICVRQIKRKV KYSEVPTSVP
60 70 80 90 100
EIKVSVPQSA STLSISKMNG SYRARVLSRN GCSPPWMDRN FETSTRSSPC
110 120 130 140 150
TSPAIASTSD SCELLGDDPR SASSMRNSMF LFNVDGNPEV IDEMEDIDER
160 170 180 190 200
SVMHYELGFY DKTDGGCIRG TLTFALRYDF IHRVLMLHVI RANNLPVEDK
210 220 230 240 250
GVTVDPYVKM YLLPERRGHC KTRICKKTND PEFNEMFSFD VSFNNLANRM
260 270 280 290 300
LQFTVYDFDR FTRHGLIGNI IMRDLFEKSD LYTWTEYTMH IVASQNKNDY
310 320 330 340 350
GDLLLFLTYS NQEEKLYINV SKAYNLRPMD ITGASDPYVK IEQTFNGKRF
360 370 380 390 400
KSKKSSTKRA NLNPVFHETL VFDIPSSQIA ETNILIQVMD WDRIGKDDLL
410 420 430 440 450
GCCILGKDSP TADGKTQWDN CLNAVPEEGQ LKNKPVGQWH SLLSEVPEAF

KNMPKAKK
Length:458
Mass (Da):52,361
Last modified:December 1, 2001 - v2
Checksum:i1C6190736EA4A0DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD68891.1.
PIRiT32059.
RefSeqiNP_503409.1. NM_071008.3.
UniGeneiCel.2778.

Genome annotation databases

EnsemblMetazoaiR12A1.2; R12A1.2; WBGene00004925.
R12A1.2a; R12A1.2a; WBGene00004925.
GeneIDi178631.
KEGGicel:CELE_R12A1.2.
UCSCiR12A1.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD68891.1.
PIRiT32059.
RefSeqiNP_503409.1. NM_071008.3.
UniGeneiCel.2778.

3D structure databases

ProteinModelPortaliO16700.
SMRiO16700.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO16700. 1 interactor.
STRINGi6239.R12A1.2.2.

Proteomic databases

PaxDbiO16700.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiR12A1.2; R12A1.2; WBGene00004925.
R12A1.2a; R12A1.2a; WBGene00004925.
GeneIDi178631.
KEGGicel:CELE_R12A1.2.
UCSCiR12A1.2.1. c. elegans.

Organism-specific databases

CTDi178631.
WormBaseiR12A1.2a; CE29448; WBGene00004925; snt-5.

Phylogenomic databases

eggNOGiENOG410IT36. Eukaryota.
ENOG410YFCM. LUCA.
GeneTreeiENSGT00760000118973.
InParanoidiO16700.
OMAiFIHRVLM.
OrthoDBiEOG091G0XMQ.
PhylomeDBiO16700.

Enzyme and pathway databases

ReactomeiR-CEL-8856825. Cargo recognition for clathrin-mediated endocytosis.
R-CEL-8856828. Clathrin-mediated endocytosis.

Gene expression databases

BgeeiWBGene00004925.
ExpressionAtlasiO16700. differential.

Family and domain databases

Gene3Di2.60.40.150. 2 hits.
InterProiIPR000008. C2_dom.
IPR001565. Synaptotagmin.
[Graphical view]
PfamiPF00168. C2. 2 hits.
[Graphical view]
PRINTSiPR00360. C2DOMAIN.
PR00399. SYNAPTOTAGMN.
SMARTiSM00239. C2. 2 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 2 hits.
PROSITEiPS50004. C2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO16700_CAEEL
AccessioniPrimary (citable) accession number: O16700
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.