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Protein
Submitted name:

Uncharacterized protein

Gene

C35A11.4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-CEL-189200. Cellular hexose transport.
R-CEL-196836. Vitamin C (ascorbate) metabolism.
R-CEL-422356. Regulation of insulin secretion.
R-CEL-5653890. Lactose synthesis.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-8981373. Intestinal hexose absorption.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:C35A11.4Imported, CELE_C35A11.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC35A11.4; CE35254; WBGene00016431.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 26HelicalSequence analysisAdd BLAST20
Transmembranei62 – 81HelicalSequence analysisAdd BLAST20
Transmembranei93 – 114HelicalSequence analysisAdd BLAST22
Transmembranei120 – 142HelicalSequence analysisAdd BLAST23
Transmembranei154 – 177HelicalSequence analysisAdd BLAST24
Transmembranei183 – 205HelicalSequence analysisAdd BLAST23
Transmembranei269 – 291HelicalSequence analysisAdd BLAST23
Transmembranei311 – 328HelicalSequence analysisAdd BLAST18
Transmembranei335 – 358HelicalSequence analysisAdd BLAST24
Transmembranei364 – 391HelicalSequence analysisAdd BLAST28
Transmembranei403 – 424HelicalSequence analysisAdd BLAST22
Transmembranei436 – 453HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiO16547.
PaxDbiO16547.

Expressioni

Gene expression databases

BgeeiWBGene00016431.

Interactioni

Protein-protein interaction databases

STRINGi6239.C35A11.4.

Structurei

3D structure databases

ProteinModelPortaliO16547.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 459MFSInterPro annotationAdd BLAST447

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili229 – 253Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
GeneTreeiENSGT00760000119022.
HOGENOMiHOG000018961.
InParanoidiO16547.
OMAiSGSMFII.
OrthoDBiEOG091G06BX.
PhylomeDBiO16547.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR036259. MFS_trans_sf.
IPR003663. Sugar/inositol_transpt.
PfamiView protein in Pfam
PF00083. Sugar_tr. 1 hit.
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiView protein in PROSITE
PS50850. MFS. 1 hit.

Sequencei

Sequence statusi: Complete.

O16547-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEAPSFRMI CVAVITSIAG SFHFGFNLVL TNPSQEAFLN FMNQTLAKRF
60 70 80 90 100
DGGLSDNTLQ NIWSFVVAIL FLGALAGSFS IRLIADWIGR KNGLYISIAV
110 120 130 140 150
GVLAGGMSIA SKFIPLFELY IASRIVMGWS VSVSLGLSAL FLSEASPKQN
160 170 180 190 200
RGAIGMMTGT CVQLGTVCGS VIAMPQIFGT EDLWWLIYAT EIGIMLFFGA
210 220 230 240 250
ALPFFPESPG FLIQRGATEA ATKSIAYYYN CEIDEAEKHL NEIKEEQKNS
260 270 280 290 300
TKNFKMMDIV RKKSLRDKAF IGVVVTFAMS FSGVAVINAF AFDILKDTGL
310 320 330 340 350
KVLEASLAND AISVVSMISS IVAAVIVDRN GRRPLLLISF AGILVCNLII
360 370 380 390 400
FALMFTFYKF ENHVLGFILI CFICIFTFFF ALGPGPLCYF INAELVGQAA
410 420 430 440 450
RSAAQSWASV IQMLSRFVIV TAFLPMKNQL GEAWSYLILF VAPVAASLVY
460 470 480 490 500
LYFSLPETKN KNPFEVEEAI EDLPKFPLCG KNRVYDRKQS QEMVLSRQMQ
510
LVVDYGSIES LSYRL
Length:515
Mass (Da):56,827
Last modified:October 1, 2003 - v2
Checksum:i6CCB2E9C2523ACB2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD65616.1.
PIRiT31930.
RefSeqiNP_504430.2. NM_072029.3.
UniGeneiCel.4584.

Genome annotation databases

EnsemblMetazoaiC35A11.4; C35A11.4; WBGene00016431.
GeneIDi178921.
KEGGicel:CELE_C35A11.4.
UCSCiC35A11.4. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiO16547_CAEEL
AccessioniPrimary (citable) accession number: O16547
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: October 1, 2003
Last modified: October 25, 2017
This is version 133 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported