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Protein
Submitted name:

Uncharacterized protein

Gene

tag-196

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Enzyme and pathway databases

ReactomeiR-CEL-2132295. MHC class II antigen presentation.

Protein family/group databases

MEROPSiC01.166.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:tag-196Imported
ORF Names:CELE_F41E6.6Imported, F41E6.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF41E6.6; CE35305; WBGene00007055; tag-196.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020UniRule annotationAdd
BLAST
Chaini21 – 477457UniRule annotationPRO_5005399888Add
BLAST

Proteomic databases

EPDiO16454.
PaxDbiO16454.

Expressioni

Gene expression databases

BgeeiWBGene00007055.

Interactioni

Protein-protein interaction databases

DIPiDIP-27400N.
IntActiO16454. 1 interaction.
MINTiMINT-1044990.
STRINGi6239.F41E6.6.1.

Structurei

3D structure databases

ProteinModelPortaliO16454.
SMRiO16454. Positions 181-477.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini174 – 23158Inhibitor_I29InterPro annotationAdd
BLAST
Domaini264 – 475212Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1542. Eukaryota.
COG4870. LUCA.
GeneTreeiENSGT00760000118871.
HOGENOMiHOG000230774.
InParanoidiO16454.
KOiK01373.
OMAiTCRFDAN.
OrthoDBiEOG091G05SD.
PhylomeDBiO16454.

Family and domain databases

InterProiIPR000010. Cystatin_dom.
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00031. Cystatin. 1 hit.
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O16454-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKPIVCLIL LLASLHTVVS KVLPINEEDQ LLYEKFARHG VEKFNQQSND
60 70 80 90 100
AYKWELDRTW EVERKLSGGI HYSIFVTLVK TDCKKGQTDV EGKKCRKTDT
110 120 130 140 150
LKKCQVEISR RVKRHGYGLK DIVHIRNCEE EFTRNIDKFD HRKIQLTHDD
160 170 180 190 200
SITVQELRKA KIIRPRDYVI WNSFLDFVDR HEKKYTNKRE VLKRFRVFKK
210 220 230 240 250
NAKVIRELQK NEQGTAVYGF TKFSDMTTME FKKIMLPYQW EQPVYPMEQA
260 270 280 290 300
NFEKHDVTIN EEDLPESFDW REKGAVTQVK NQGNCGSCWA FSTTGNVEGA
310 320 330 340 350
WFIAKNKLVS LSEQELVDCD SMDQGCNGGL PSNAYKEIIR MGGLEPEDAY
360 370 380 390 400
PYDGRGETCH LVRKDIAVYI NGSVELPHDE VEMQKWLVTK GPISIGLNAN
410 420 430 440 450
TLQFYRHGVV HPFKIFCEPF MLNHGVLIVG YGKDGRKPYW IVKNSWGPNW
460 470
GEAGYFKLYR GKNVCGVQEM ATSALVN
Length:477
Mass (Da):55,216
Last modified:March 1, 2004 - v2
Checksum:i2B8110AF8077BB1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD64084.1.
PIRiT31871.
RefSeqiNP_505215.2. NM_072814.3.
UniGeneiCel.5581.

Genome annotation databases

EnsemblMetazoaiF41E6.6.1; F41E6.6.1; WBGene00007055.
F41E6.6.2; F41E6.6.2; WBGene00007055.
GeneIDi179240.
KEGGicel:CELE_F41E6.6.
UCSCiF41E6.6.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD64084.1.
PIRiT31871.
RefSeqiNP_505215.2. NM_072814.3.
UniGeneiCel.5581.

3D structure databases

ProteinModelPortaliO16454.
SMRiO16454. Positions 181-477.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-27400N.
IntActiO16454. 1 interaction.
MINTiMINT-1044990.
STRINGi6239.F41E6.6.1.

Protein family/group databases

MEROPSiC01.166.

Proteomic databases

EPDiO16454.
PaxDbiO16454.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF41E6.6.1; F41E6.6.1; WBGene00007055.
F41E6.6.2; F41E6.6.2; WBGene00007055.
GeneIDi179240.
KEGGicel:CELE_F41E6.6.
UCSCiF41E6.6.1. c. elegans.

Organism-specific databases

CTDi179240.
WormBaseiF41E6.6; CE35305; WBGene00007055; tag-196.

Phylogenomic databases

eggNOGiKOG1542. Eukaryota.
COG4870. LUCA.
GeneTreeiENSGT00760000118871.
HOGENOMiHOG000230774.
InParanoidiO16454.
KOiK01373.
OMAiTCRFDAN.
OrthoDBiEOG091G05SD.
PhylomeDBiO16454.

Enzyme and pathway databases

ReactomeiR-CEL-2132295. MHC class II antigen presentation.

Gene expression databases

BgeeiWBGene00007055.

Family and domain databases

InterProiIPR000010. Cystatin_dom.
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00031. Cystatin. 1 hit.
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO16454_CAEEL
AccessioniPrimary (citable) accession number: O16454
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: March 1, 2004
Last modified: September 7, 2016
This is version 132 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.