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Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-33c4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-193048. Androgen biosynthesis.
R-CEL-193993. Mineralocorticoid biosynthesis.
R-CEL-194002. Glucocorticoid biosynthesis.
R-CEL-211957. Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2.
R-CEL-211976. Endogenous sterols.
R-CEL-211981. Xenobiotics.
R-CEL-2142670. Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET).
R-CEL-2142816. Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).
R-CEL-5423646. Aflatoxin activation and detoxification.

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-33c4Imported
Synonyms:cyp-33C4Imported
ORF Names:CELE_F44C8.1Imported, F44C8.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF44C8.1; CE10378; WBGene00018413; cyp-33C4.

PTM / Processingi

Proteomic databases

EPDiO16362.
PaxDbiO16362.
PRIDEiO16362.

Expressioni

Gene expression databases

BgeeiWBGene00018413.

Interactioni

Protein-protein interaction databases

STRINGi6239.F44C8.1.

Structurei

3D structure databases

ProteinModelPortaliO16362.
SMRiO16362. Positions 25-464.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118992.
HOGENOMiHOG000036993.
InParanoidiO16362.
KOiK17955.
OrthoDBiEOG091G0BT8.
PhylomeDBiO16362.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O16362-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIILLVFTAF LAFLFHELYW KRRNLPPGPI PLPFMGNILT MLLNKPGYEC
60 70 80 90 100
FRNCTKKYGD VYTFWMGKTP FVMISSYDLL KDTFVRDGDT YKDKYPQPLN
110 120 130 140 150
QKIRGGNYGI VESNGHLWST HRRFALTTLR DFGLGKDLMQ EKILIEVEDI
160 170 180 190 200
FKKFDAQLGL EQDVSVVMNN AIANVINQNI FGYRFEGDKE EDFKKLRELM
210 220 230 240 250
EYQETAFATF KVYVEAFIPK VGALLPGRSL NELLEEWRDN FYTFFDTQIE
260 270 280 290 300
NHRKKIDFDS QESLDYAEAY LKEQRKQEAL GEFELFSNKQ LSNTCLDLWL
310 320 330 340 350
AGLSTTNTTV NWTICYVLNH PDVLQKMNEE FDQVVGSDRL VTMGDKNNLP
360 370 380 390 400
YFNAVLNESQ RCANIVPINL FHATTKDTVI NGYPVKKGTG VIAQISTVML
410 420 430 440 450
DEKIFPDPYK FNPDRFIDEN GKPIKIEQLI PFSIGKRQCP GEGLARMEMF
460 470 480 490
LFLANFFNRY KISPSSKGFP NLDKKDNVGV FPKDLHAILN KRN
Length:493
Mass (Da):57,079
Last modified:January 1, 1998 - v1
Checksum:i643DBBC0D48A9750
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71001.1.
PIRiT31794.
RefSeqiNP_503612.1. NM_071211.3.
UniGeneiCel.30999.

Genome annotation databases

EnsemblMetazoaiF44C8.1; F44C8.1; WBGene00018413.
GeneIDi178704.
KEGGicel:CELE_F44C8.1.
UCSCiF44C8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD71001.1.
PIRiT31794.
RefSeqiNP_503612.1. NM_071211.3.
UniGeneiCel.30999.

3D structure databases

ProteinModelPortaliO16362.
SMRiO16362. Positions 25-464.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F44C8.1.

Proteomic databases

EPDiO16362.
PaxDbiO16362.
PRIDEiO16362.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF44C8.1; F44C8.1; WBGene00018413.
GeneIDi178704.
KEGGicel:CELE_F44C8.1.
UCSCiF44C8.1. c. elegans.

Organism-specific databases

CTDi178704.
WormBaseiF44C8.1; CE10378; WBGene00018413; cyp-33C4.

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00760000118992.
HOGENOMiHOG000036993.
InParanoidiO16362.
KOiK17955.
OrthoDBiEOG091G0BT8.
PhylomeDBiO16362.

Enzyme and pathway databases

ReactomeiR-CEL-156581. Methylation.
R-CEL-193048. Androgen biosynthesis.
R-CEL-193993. Mineralocorticoid biosynthesis.
R-CEL-194002. Glucocorticoid biosynthesis.
R-CEL-211957. Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2.
R-CEL-211976. Endogenous sterols.
R-CEL-211981. Xenobiotics.
R-CEL-2142670. Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET).
R-CEL-2142816. Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE).
R-CEL-5423646. Aflatoxin activation and detoxification.

Gene expression databases

BgeeiWBGene00018413.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO16362_CAEEL
AccessioniPrimary (citable) accession number: O16362
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.