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Protein
Submitted name:

Cysteine PRotease related

Gene

cpr-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseImported

Enzyme and pathway databases

ReactomeiR-CEL-1442490. Collagen degradation.
R-CEL-1679131. Trafficking and processing of endosomal TLR.

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine PRotease relatedImported
Gene namesi
Name:cpr-8Imported
ORF Names:CELE_W07B8.1Imported, W07B8.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiW07B8.1a; CE14674; WBGene00021070; cpr-8.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717UniRule annotationAdd
BLAST
Chaini18 – 335318UniRule annotationPRO_5005399889Add
BLAST

Proteomic databases

EPDiO16289.
PaxDbiO16289.
PRIDEiO16289.

Interactioni

Protein-protein interaction databases

STRINGi6239.W07B8.1.

Structurei

3D structure databases

ProteinModelPortaliO16289.
SMRiO16289. Positions 24-333.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini76 – 331256Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000241341.
InParanoidiO16289.
KOiK01363.
OMAiTGIYVHL.
OrthoDBiEOG7034HR.
PhylomeDBiO16289.

Family and domain databases

InterProiIPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O16289-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKILICLIG VLFQADGVPP SEIDRIIHYV NSQKTTWTAG IPALSRNSML
60 70 80 90 100
KTLVTDAATI GFKIQNFGVS QANSDLSPSF DARERWPECM SIPQINDISE
110 120 130 140 150
CKTSWAFAAA ESMSDRLCIN SGGFKNTILS AEELLSCCTG MFSCGEGCEG
160 170 180 190 200
GNPFKAWQYI QKHGIPTGGS YESQFGCKPY SIPPCGKTVG NVTYPACTNT
210 220 230 240 250
TSPTPSCEKK CTSRIGYPID IDKDRHYGVS VDQLPNSQIE IQSDVMLNGP
260 270 280 290 300
IQATFEVYDD FLQYTTGIYV HLTGNKQGHL SVRIIGWGVW QGVPYWLCAN
310 320 330
SWGRQWGENG TFRVLRGTNE CGLESNCVSG MPKLN
Length:335
Mass (Da):36,781
Last modified:January 1, 1998 - v1
Checksum:iBC1E664A8205BCA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD74286.1.
PIRiT31730.
RefSeqiNP_503384.1. NM_070983.5.
UniGeneiCel.1985.

Genome annotation databases

EnsemblMetazoaiW07B8.1; W07B8.1; WBGene00021070.
W07B8.1a; W07B8.1a; WBGene00021070.
GeneIDi178613.
KEGGicel:CELE_W07B8.1.
UCSCiW07B8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD74286.1.
PIRiT31730.
RefSeqiNP_503384.1. NM_070983.5.
UniGeneiCel.1985.

3D structure databases

ProteinModelPortaliO16289.
SMRiO16289. Positions 24-333.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.W07B8.1.

Proteomic databases

EPDiO16289.
PaxDbiO16289.
PRIDEiO16289.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW07B8.1; W07B8.1; WBGene00021070.
W07B8.1a; W07B8.1a; WBGene00021070.
GeneIDi178613.
KEGGicel:CELE_W07B8.1.
UCSCiW07B8.1. c. elegans.

Organism-specific databases

CTDi178613.
WormBaseiW07B8.1a; CE14674; WBGene00021070; cpr-8.

Phylogenomic databases

eggNOGiKOG1543. Eukaryota.
COG4870. LUCA.
HOGENOMiHOG000241341.
InParanoidiO16289.
KOiK01363.
OMAiTGIYVHL.
OrthoDBiEOG7034HR.
PhylomeDBiO16289.

Enzyme and pathway databases

ReactomeiR-CEL-1442490. Collagen degradation.
R-CEL-1679131. Trafficking and processing of endosomal TLR.

Family and domain databases

InterProiIPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF00112. Peptidase_C1. 1 hit.
[Graphical view]
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO16289_CAEEL
AccessioniPrimary (citable) accession number: O16289
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.