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Protein

Putative histone H1.6

Gene

hil-6

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative histone H1.6
Alternative name(s):
Histone H1-like protein 6
Gene namesi
Name:hil-6
ORF Names:F59A7.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF59A7.4; CE11442; WBGene00001857; hil-6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001959862 – 190Putative histone H1.6Add BLAST189

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiO16277.
PaxDbiO16277.
PeptideAtlasiO16277.
PRIDEiO16277.

Expressioni

Gene expression databases

BgeeiWBGene00001857.

Interactioni

Protein-protein interaction databases

BioGridi51320. 1 interactor.
STRINGi6239.F59A7.4.

Structurei

3D structure databases

ProteinModelPortaliO16277.
SMRiO16277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 110H15PROSITE-ProRule annotationAdd BLAST77

Sequence similaritiesi

Belongs to the histone H1/H5 family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4012. Eukaryota.
ENOG4112541. LUCA.
GeneTreeiENSGT00730000111466.
HOGENOMiHOG000251627.
InParanoidiO16277.
KOiK11275.
OMAiSKWITAN.
OrthoDBiEOG091G0XGD.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR005818. Histone_H1/H5_H15.
IPR005819. Histone_H5.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00538. Linker_histone. 1 hit.
PRINTSiPR00624. HISTONEH5.
SMARTiView protein in SMART
SM00526. H15. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS51504. H15. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O16277-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDVAVAETP AVKTPTKAPK ANATKVPKVK TAAAHPPFIN MVTAAISSLK
60 70 80 90 100
ERKGSSKIAI LKYITANYKL GDQVKKINSN LRSALKKGVA SKALVQTVGT
110 120 130 140 150
GATGRFRVAE KTAATAKKPT VKKAATGEKV KKTVVKKTVA KKTGDKVKKA
160 170 180 190
KSPKKIAKPA AKKATKSPSK KVAPKKAAAK PAKKTAALKA
Length:190
Mass (Da):19,747
Last modified:January 23, 2007 - v3
Checksum:i91A58F0A00C54525
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD72097.1.
PIRiA88961.
RefSeqiNP_503554.1. NM_071153.1.
UniGeneiCel.3300.

Genome annotation databases

EnsemblMetazoaiF59A7.4; F59A7.4; WBGene00001857.
GeneIDi186584.
KEGGicel:CELE_F59A7.4.
UCSCiF59A7.4. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiH16_CAEEL
AccessioniPrimary (citable) accession number: O16277
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: January 23, 2007
Last modified: September 27, 2017
This is version 102 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Caution

PubMed:11245572 has not been able to detect expression of this protein.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families