ID   TPM_ECHGR               Reviewed;         278 AA.
AC   O16127;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 3.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Tropomyosin A;
DE            Short=EgTrpA;
DE   Flags: Fragment;
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC   Echinococcus granulosus group.
OX   NCBI_TaxID=6210;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Esteves A., Senorale M., Fernandez C., Bruzzone H., Ehrlich R.;
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- DOMAIN: The molecule is in a coiled coil structure that is formed by 2
CC       polypeptide chains. The sequence exhibits a prominent seven-residues
CC       periodicity.
CC   -!- SIMILARITY: Belongs to the tropomyosin family. {ECO:0000305}.
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DR   EMBL; AF011923; AAB65799.4; -; mRNA.
DR   AlphaFoldDB; O16127; -.
DR   SMR; O16127; -.
DR   Gene3D; 1.20.5.170; -; 2.
DR   Gene3D; 1.20.5.340; -; 1.
DR   InterPro; IPR000533; Tropomyosin.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   PANTHER; PTHR19269:SF45; TROPOMYOSIN-1, ISOFORMS 33_34; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat.
FT   CHAIN           <1..278
FT                   /note="Tropomyosin A"
FT                   /id="PRO_0000205652"
FT   REGION          92..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          <1..270
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        105..134
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
SQ   SEQUENCE   278 AA;  32269 MW;  5227AEEB1B358885 CRC64;
     IMMAMKLEKE NALEKAINLE NQLKEKAKDF EKKEEEMNDW LSKVKNIQTE VDTVQESLQE
     AISKLEETEK RATNAEAEVA AMTRRIRLLE EDFEQSSGRL TETSTKLDDA SKAAEESERN
     RKTLETRSIS DDERMAQLEE QVKEAKYIAE DAERKYDEAA RRLAVTEVDL ERAESRLETS
     ESKIVELEEE LRIVGNNMKS LEVSEQESLQ REESYEETIR DLTERLKTAE QRAAEAERQV
     SKLQNEVDRL EDELLSEKER YRAISGELDT TFAELTSF
//