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Reviewed, UniProtKB/Swiss-Prot O16098 (MAL1_DROVI)

Last modified January 19, 2010. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Maltase 1
    EC=3.2.1.20
Gene names
Name: Mav1
OrganismDrosophila virilis (Fruit fly)
Taxonomic identifier7244 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila

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Protein attributes

Sequence length586 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 13 family.

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Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionalpha-glucosidase activity

Inferred from electronic annotation. Source: EC

cation binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 586567Maltase 1
PRO_0000001449

Amino acid modifications

Glycosylation1331N-linked (GlcNAc...) Potential
Glycosylation1661N-linked (GlcNAc...) Potential
Glycosylation2871N-linked (GlcNAc...) Potential
Glycosylation4151N-linked (GlcNAc...) Potential
Glycosylation5291N-linked (GlcNAc...) Potential
Glycosylation5321N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
O16098-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: FD88C62F5AF6C868

FASTA58667,544
        10         20         30         40         50         60 
MSLKWSLVLG LSWLLFVASS ELKKHKPNEL DDNINWWRHE VFYQIYPRSF KDSDGDGIGD 

        70         80         90        100        110        120 
LKGITSKLQY FVDTGITAIW LSPIYKSPMV DFGYDISDYR DIQPEYGTLE DFDALIAKAN 

       130        140        150        160        170        180 
QLGIKVILDF VPNHSSDEHE WFKKSAAREP GYEDFYVWED GIPGDNETRL PPNNWVSVFS 

       190        200        210        220        230        240 
GSAWQWHEER QQFYLRQFTK GQPDLNYRNP AVVQAMDEVL LYWLQKGVAG FRIDAVIYIY 

       250        260        270        280        290        300 
EDEQLRDEPL SGSTSDPNSV DYLEHIYTRN LPECYGLIQH WRQLLDNYTA DNPGPVRIMM 

       310        320        330        340        350        360 
TEGYADLSLL MNYYEDEDGV QGAHFPFNFD FITELNANSA APDFVYFIQR WLTYMPPGHS 

       370        380        390        400        410        420 
ANWVMGNHDN PRVASRYGVG TVDAMNMLMM TLPGIGITYY GEELGMVDYR DISWNDTVDQ 

       430        440        450        460        470        480 
PACDAGLDNY KWVSRDPERT PMQWSDEKNA GFSTGDSTWL PVHPNYQELN LLTQQEATYS 

       490        500        510        520        530        540 
HYKVYQSLIK LRQSRVLRDG SFTAQALNRN VFAIKRELRG QPTLLTVINV SNRTQQVDVS 

       550        560        570        580 
NFIDLPNRLT LLVVGVCSQH RVSERLKPAE VKLSPHEGLV IQLKAR

« Hide

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References

[1]"The evolution of small gene clusters: evidence for an independent origin of the maltase gene cluster in Drosophila virilis and Drosophila melanogaster."
Vieira C.P., Vieira J., Hartl D.L.
Mol. Biol. Evol. 14:985-993(1997) [PubMed: 9335139] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 9.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF006573 Genomic DNA. Translation: AAB82327.1.

3D structure databases

ModBaseSearch...

Protein family/group databases

CAZyGH13. Glycoside Hydrolase Family 13.

Organism-specific databases

FlyBaseFBgn0022839. Dvir\Mav1.

Phylogenomic databases

InParanoidO16098.

Enzyme and pathway databases

BRENDA3.2.1.20. 141708.

Family and domain databases

InterProIPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR017853. Glyco_hydro_catalytic_core.
IPR013781. Glyco_hydro_sg_catalytic.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTSM00642. Aamy. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameMAL1_DROVI
AccessionPrimary (citable) accession number: O16098
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: January 19, 2010
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectDrosophila annotation project

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Relevant documents

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents