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Protein
Submitted name:

LD39986p

Gene

Rab10

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro

GO - Biological processi

  • basal protein localization Source: FlyBase
  • cellular response to insulin stimulus Source: GO_Central
  • growth of a germarium-derived egg chamber Source: FlyBase
  • lateral inhibition Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • vesicle-mediated transport Source: FlyBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DME-1445148. Translocation of GLUT4 to the plasma membrane.
R-DME-6798695. Neutrophil degranulation.
R-DME-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Submitted name:
LD39986pImported
Submitted name:
Rab10Imported
Gene namesi
Name:Rab10Imported
Synonyms:DRab10Imported
ORF Names:CG17060Imported, Dmel_CG17060Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0015789. Rab10.

Subcellular locationi

GO - Cellular componenti

  • basal part of cell Source: FlyBase
  • cell trailing edge Source: FlyBase
  • cytoplasm Source: FlyBase
  • Golgi apparatus Source: GO_Central
  • insulin-responsive compartment Source: GO_Central
  • neuronal cell body Source: FlyBase
  • recycling endosome Source: FlyBase
  • synapse Source: FlyBase
  • vesicle Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0015789.

Interactioni

Protein-protein interaction databases

DIPiDIP-59995N.
STRINGi7227.FBpp0077029.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
GeneTreeiENSGT00860000133675.
KOiK07903.
OMAiNINEHAN.
OrthoDBiEOG091G0LA6.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

O15971-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKTYDLLF KLLLIGDSGV GKTCILFRFS DDAFTSTFIS TIGIDFKIKT
60 70 80 90 100
VELRGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNEKSFENI
110 120 130 140 150
VKWLRNIDEH ANEDVEKMIL GNKCDMTDKR VVNKERGEAI AREHGIRFME
160 170 180 190 200
TSAKSNINIE RAFCELAEAI LDKTSGRESA ENQERVIIDR RNQEKAPGYS

KCCA
Length:204
Mass (Da):23,336
Last modified:January 1, 1998 - v1
Checksum:i4E058761C6854920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF50924.1.
AY060425 mRNA. Translation: AAL25464.1.
AB006189 mRNA. Translation: BAA21744.1.
RefSeqiNP_523419.1. NM_078695.4.
UniGeneiDm.2609.

Genome annotation databases

EnsemblMetazoaiFBtr0077337; FBpp0077029; FBgn0015789.
GeneIDi33025.
KEGGidme:Dmel_CG17060.
UCSCiCG17060-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF50924.1.
AY060425 mRNA. Translation: AAL25464.1.
AB006189 mRNA. Translation: BAA21744.1.
RefSeqiNP_523419.1. NM_078695.4.
UniGeneiDm.2609.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59995N.
STRINGi7227.FBpp0077029.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0077337; FBpp0077029; FBgn0015789.
GeneIDi33025.
KEGGidme:Dmel_CG17060.
UCSCiCG17060-RA. d. melanogaster.

Organism-specific databases

CTDi10890.
FlyBaseiFBgn0015789. Rab10.

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
GeneTreeiENSGT00860000133675.
KOiK07903.
OMAiNINEHAN.
OrthoDBiEOG091G0LA6.

Enzyme and pathway databases

ReactomeiR-DME-1445148. Translocation of GLUT4 to the plasma membrane.
R-DME-6798695. Neutrophil degranulation.
R-DME-8876198. RAB GEFs exchange GTP for GDP on RABs.

Miscellaneous databases

GenomeRNAii33025.

Gene expression databases

BgeeiFBgn0015789.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO15971_DROME
AccessioniPrimary (citable) accession number: O15971
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 142 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.