dut

Functionⁱ

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	48	Calcium 1Combined sources	1
Metal bindingⁱ	48	Calcium 2Combined sources	1
Metal bindingⁱ	48	MagnesiumCombined sources	1
Metal bindingⁱ	51	Calcium 1Combined sources	1
Metal bindingⁱ	51	Calcium 2Combined sources	1
Metal bindingⁱ	51	MagnesiumCombined sources	1
Metal bindingⁱ	76	Calcium 2Combined sources	1
Metal bindingⁱ	76	MagnesiumCombined sources	1
Metal bindingⁱ	79	Calcium 2Combined sources	1
Metal bindingⁱ	79	MagnesiumCombined sources	1

GO - Molecular functionⁱ

dUTP diphosphatase activity Source: UniProtKB-EC
metal ion binding Source: UniProtKB-KW

Complete GO annotation...

Keywordsⁱ

Molecular function	HydrolaseImported
Ligand	CalciumCombined sources, MagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: DUTPaseImported (EC:3.6.1.23Imported) Submitted name: Putative deoxyuridine triphosphataseImported
Gene namesⁱ	Name:dutImported Synonyms:DUTImported ORF Names:LMJF_06_0560Imported
Organismⁱ	Leishmania majorImported
Taxonomic identifierⁱ	5664 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmaniinae › Leishmania › Leishmania › Leishmania major species complex
Proteomesⁱ	UP000000542 Componentⁱ: Chromosome 6

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL4418.

ChEMBLⁱ

CHEMBL4418.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	5664.LmjF.06.0560.

STRINGⁱ

5664.LmjF.06.0560.

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2CJE	X-ray	2.34	A	1-268	[»]
	2YAY	X-ray	1.86	A	1-268	[»]
	2YAZ	X-ray	2.40	A/B/D/E	1-268	[»]
	2YB0	X-ray	2.28	A/B/D/E	1-268	[»]
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410K2HU. Eukaryota. ENOG4112CGJ. LUCA.
HOGENOMⁱ	HOG000255273.
KEGG Orthology (KO) More...KOⁱ	K01520.
OMAⁱ	FRQDHGY.

Family and domain databases

InterProⁱ	View protein in InterPro IPR014871. dUTPase/dCTP_pyrophosphatase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08761. dUTPase_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

O15826-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKRARSANIP GAILHSLAEL QDGLNAMIDP SWRAVRSLDN WALAITMEST 
        60         70         80         90        100
ELLDSYPWKW WKNLNATPDL ANVRIELVDI FHFSLSGAMQ MRSTPDDEIP 
       110        120        130        140        150
AASLKPLKEV MTTFLPAKEC TSDPYGFVFF PLTDTQNAIA SFRNIIQLAN 
       160        170        180        190        200
AYRFDVIIEC IIYAAEDLGF NLVAYYIAKH TLNCIRQLSG YKDGSYVKVN 
       210        220        230        240        250
NGVEDNSLLH NCIKDVSLDE VLDADKYVQA WNSIMANVYE AFQIKESDRK 
       260 
DAERWFALAK ENRLAIKA

Length:268

Mass (Da):30,354

Last modified:January 1, 1998 - v1

Checksum:ⁱB1F230CD5752F5F1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L76742 mRNA. Translation: AAC02795.1. FR796402 Genomic DNA. Translation: CAJ02101.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_001680826.1. XM_001680774.1.

Genome annotation databases

EnsemblProtistsⁱ	LmjF.06.0560:mRNA; LmjF.06.0560:pep; LmjF.06.0560.
GeneDBⁱ	LmjF.06.0560:pep.
GeneIDⁱ	5649078.
KEGGⁱ	lma:LMJF_06_0560.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L76742 mRNA. Translation: AAC02795.1. FR796402 Genomic DNA. Translation: CAJ02101.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_001680826.1. XM_001680774.1.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2CJE	X-ray	2.34	A	1-268	[»]
	2YAY	X-ray	1.86	A	1-268	[»]
	2YAZ	X-ray	2.40	A/B/D/E	1-268	[»]
	2YB0	X-ray	2.28	A/B/D/E	1-268	[»]
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	5664.LmjF.06.0560.

STRINGⁱ

5664.LmjF.06.0560.

Chemistry databases

ChEMBLⁱ	CHEMBL4418.

ChEMBLⁱ

CHEMBL4418.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblProtistsⁱ	LmjF.06.0560:mRNA; LmjF.06.0560:pep; LmjF.06.0560.
GeneDBⁱ	LmjF.06.0560:pep.
GeneIDⁱ	5649078.
KEGGⁱ	lma:LMJF_06_0560.

Phylogenomic databases

eggNOGⁱ	ENOG410K2HU. Eukaryota. ENOG4112CGJ. LUCA.
HOGENOMⁱ	HOG000255273.
KEGG Orthology (KO) More...KOⁱ	K01520.
OMAⁱ	FRQDHGY.

Family and domain databases

InterProⁱ	View protein in InterPro IPR014871. dUTPase/dCTP_pyrophosphatase.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08761. dUTPase_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O15826_LEIMA
Accessionⁱ	O15826Primary (citable) accession number: O15826 Secondary accession number(s): Q4QJ22
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	January 1, 1998
	Last sequence update:	January 1, 1998
	Last modified:	May 10, 2017
	This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - O15826 (O15826_LEIMA)

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DUTPase

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Functionⁱ

Sites

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Chemistry databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O15826 (O15826_LEIMA)

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DUTPase

dut

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ