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Protein

Protein tipD

Gene

tipD

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Not known; disruption of the gene for tipD results in morphological defects.

GO - Molecular functioni

GO - Biological processi

  • autophagosome assembly Source: dictyBase
  • culmination involved in sorocarp development Source: dictyBase
  • macroautophagy Source: dictyBase
  • phagocytosis Source: dictyBase
  • phagosome maturation Source: dictyBase
  • pinocytosis Source: dictyBase
  • proteasome-mediated ubiquitin-dependent protein catabolic process Source: dictyBase
  • sorocarp development Source: dictyBase

Enzyme and pathway databases

ReactomeiR-DDI-1632852 Macroautophagy

Names & Taxonomyi

Protein namesi
Recommended name:
Protein tipD
Gene namesi
Name:tipD
ORF Names:DDB_G0275323
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0275323 tipD

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000512751 – 612Protein tipDAdd BLAST612

Proteomic databases

PaxDbiO15736
PRIDEiO15736

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0215341

Structurei

3D structure databases

ProteinModelPortaliO15736
SMRiO15736
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati322 – 361WD 1Add BLAST40
Repeati364 – 403WD 2Add BLAST40
Repeati406 – 444WD 3Add BLAST39
Repeati447 – 486WD 4Add BLAST40
Repeati490 – 530WD 5Add BLAST41
Repeati535 – 576WD 6Add BLAST42
Repeati582 – 611WD 7Add BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi10 – 13Poly-Met4
Compositional biasi14 – 19Poly-Gly6
Compositional biasi113 – 120Poly-Ser8

Sequence similaritiesi

Belongs to the WD repeat tipD family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG0288 Eukaryota
ENOG410XQYA LUCA
InParanoidiO15736
KOiK17890
OMAiNAVKQTF
PhylomeDBiO15736

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR024977 Apc4_WD40_dom
IPR013923 Autophagy-rel_prot_16
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12894 ANAPC4_WD40, 1 hit
PF08614 ATG16, 1 hit
PF00400 WD40, 4 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 5 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O15736-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSSQNNSYM MMMGGGGIGN INNNQFYSPI ISTSAQSFNS IVEWKRDIIR
60 70 80 90 100
QLNDRNQNQT NNYSEFMRIY TDLLKRERTL NDRTLLYEKE IVSLRNEKKT
110 120 130 140 150
QQQPPSGSSK MDSSSSSSSS NRVSGMGSTI EEMEQKLFKL QEDLTNSYKR
160 170 180 190 200
NADNASSILL LNDKNKDLQN ELMSKEIEIE RIRSTIQQDL DSIKRLEMVV
210 220 230 240 250
IEKENVSQII RDELSSLQTE FLHNESKVVK LEQENSSLVE RWLRKKNEEA
260 270 280 290 300
SKMNEANDFY QKMVEQRDST PAKAAVQLSE SISNLVVKLP DANDVPIPIV
310 320 330 340 350
LERGVFSSEA MLPSKAKKRW TGHNSEIYCM AFNSIGNLLA TGGGDKCVKV
360 370 380 390 400
WDVISGQQKS TLLGASQSIV SVSFSPNDES ILGTSNDNSA RLWNTELGRS
410 420 430 440 450
RHTLTGHIGK VYTGKFINSN RVVTGSHDRT IKLWDLQKGY CTRTIFCFSS
460 470 480 490 500
CNDLVILGGS GTHLASGHVD HSVRFWDSNA GEPTQVLSSI HEGQITSITN
510 520 530 540 550
SPTNTNQILT NSRDHTLKII DIRTFDTIRT FKDPEYRNGL NWTKASWSPD
560 570 580 590 600
GRYIASGSID GSICIWDATN GKTVKVLTKV HNNGSSVCCC SWSPLANIFI
610
SADKDKNIIQ WE
Length:612
Mass (Da):68,747
Last modified:January 1, 1998 - v1
Checksum:i4DB6D03EDEC0B6E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019236 Genomic DNA Translation: AAB70659.1
AAFI02000013 Genomic DNA Translation: EAL69727.1
PIRiT08602
RefSeqiXP_643673.1, XM_638581.1

Genome annotation databases

EnsemblProtistsiEAL69727; EAL69727; DDB_G0275323
GeneIDi8619939
KEGGiddi:DDB_G0275323

Similar proteinsi

Entry informationi

Entry nameiTIPD_DICDI
AccessioniPrimary (citable) accession number: O15736
Secondary accession number(s): Q553S4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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