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O15504

- NUPL2_HUMAN

UniProt

O15504 - NUPL2_HUMAN

Protein

Nucleoporin-like protein 2

Gene

NUPL2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 108 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.2 Publications

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri1 – 2525C3H1-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. nuclear export signal receptor activity Source: ProtInc
    3. poly(A) RNA binding Source: UniProtKB

    GO - Biological processi

    1. carbohydrate metabolic process Source: Reactome
    2. cytokine-mediated signaling pathway Source: Reactome
    3. glucose transport Source: Reactome
    4. hexose transport Source: Reactome
    5. mitotic cell cycle Source: Reactome
    6. mitotic nuclear envelope disassembly Source: Reactome
    7. mRNA transport Source: UniProtKB-KW
    8. protein export from nucleus Source: ProtInc
    9. regulation of glucose transport Source: Reactome
    10. small molecule metabolic process Source: Reactome
    11. transmembrane transport Source: Reactome
    12. viral process Source: Reactome

    Keywords - Biological processi

    mRNA transport, Protein transport, Translocation, Transport

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    ReactomeiREACT_115831. ISG15 antiviral mechanism.
    REACT_163931. Nuclear Pore Complex (NPC) Disassembly.
    REACT_6190. Rev-mediated nuclear export of HIV RNA.
    REACT_6804. Regulation of Glucokinase by Glucokinase Regulatory Protein.
    REACT_7991. Vpr-mediated nuclear import of PICs.
    REACT_9395. Nuclear import of Rev protein.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleoporin-like protein 2
    Alternative name(s):
    NLP-1
    NUP42 homolog
    Nucleoporin hCG1
    Gene namesi
    Name:NUPL2
    Synonyms:CG1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:17010. NUPL2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Reactome
    2. nuclear membrane Source: UniProtKB-SubCell
    3. nuclear pore Source: UniProtKB-SubCell
    4. nucleus Source: HPA

    Keywords - Cellular componenti

    Membrane, Nuclear pore complex, Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134990469.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 423423Nucleoporin-like protein 2PRO_0000204895Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei106 – 1061Phosphoserine1 Publication

    Post-translational modificationi

    O-glycosylated.1 Publication

    Keywords - PTMi

    Glycoprotein, Phosphoprotein

    Proteomic databases

    MaxQBiO15504.
    PaxDbiO15504.
    PRIDEiO15504.

    PTM databases

    PhosphoSiteiO15504.

    Expressioni

    Tissue specificityi

    Ubiquitously expressed.1 Publication

    Gene expression databases

    ArrayExpressiO15504.
    BgeeiO15504.
    CleanExiHS_NUPL2.
    GenevestigatoriO15504.

    Organism-specific databases

    HPAiHPA049036.
    HPA057251.

    Interactioni

    Subunit structurei

    Probable component of the nuclear pore complex (NPC). Interacts with nuclear export protein NXF1. Interacts with GLE1. Able to form a heterotrimer with NUP155 and GLE1 in vitro. Interacts with the HIV-1 virus proteins Rev and Vpr. The interaction with HIV-1 Rev, a protein that mediates nuclear export of unspliced viral RNAs, suggests that its function may be bypassed by the HIV-1 virus.4 Publications

    Protein-protein interaction databases

    BioGridi116278. 9 interactions.
    IntActiO15504. 6 interactions.
    MINTiMINT-4786853.
    STRINGi9606.ENSP00000258742.

    Structurei

    3D structure databases

    ProteinModelPortaliO15504.
    SMRiO15504. Positions 1-26.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati14 – 152FG 1
    Repeati95 – 962FG 2
    Repeati218 – 2192FG 3
    Repeati220 – 2212FG 4
    Repeati265 – 2662FG 5
    Repeati271 – 2722FG 6
    Repeati288 – 2892FG 7
    Repeati290 – 2912FG 8
    Repeati311 – 3122FG 9
    Repeati336 – 3372FG 10
    Repeati345 – 3462FG 11
    Repeati364 – 3652FG 12

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni94 – 17077Interaction with HIV-1 VprAdd
    BLAST
    Regioni365 – 42359Interaction with GLE1Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi238 – 378141Ser-richAdd
    BLAST

    Domaini

    The FG repeats are interaction sites for karyopherins (importins, exportins) and form probably an affinity gradient, guiding the transport proteins unidirectionally with their cargo through the NPC.By similarity

    Sequence similaritiesi

    Contains 1 C3H1-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri1 – 2525C3H1-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG69917.
    HOGENOMiHOG000113895.
    HOVERGENiHBG082070.
    InParanoidiO15504.
    KOiK14321.
    OrthoDBiEOG70ZZQ7.
    PhylomeDBiO15504.
    TreeFamiTF106503.

    Family and domain databases

    InterProiIPR000571. Znf_CCCH.
    [Graphical view]
    PROSITEiPS50103. ZF_C3H1. 1 hit.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: O15504-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAICQFFLQG RCRFGDRCWN EHPGARGAGG GRQQPQQQPS GNNRRGWNTT    50
    SQRYSNVIQP SSFSKSTPWG GSRDQEKPYF SSFDSGASTN RKEGFGLSEN 100
    PFASLSPDEQ KDEKKLLEGI VKDMEVWESS GQWMFSVYSP VKKKPNISGF 150
    TDISPEELRL EYHNFLTSNN LQSYLNSVQR LINQWRNRVN ELKSLNISTK 200
    VALLSDVKDG VNQAAPAFGF GSSQAATFMS PGFPVNNSSS DNAQNFSFKT 250
    NSGFAAASSG SPAGFGSSPA FGAAASTSSG ISTSAPAFGF GKPEVTSAAS 300
    FSFKSPAASS FGSPGFSGLP ASLATGPVRA PVAPAFGGGS SVAGFGSPGS 350
    HSHTAFSKPS SDTFGNSSIS TSLSASSSII ATDNVLFTPR DKLTVEELEQ 400
    FQSKKFTLGK IPLKPPPLEL LNV 423
    Length:423
    Mass (Da):44,872
    Last modified:January 1, 1998 - v1
    Checksum:i6F8B95073312E999
    GO
    Isoform 2 (identifier: O15504-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         204-224: LSDVKDGVNQAAPAFGFGSSQ → KCLWKIYTHLSPKIYGPDCAL
         225-423: Missing.

    Show »
    Length:224
    Mass (Da):25,542
    Checksum:i2EBE880F1494052D
    GO
    Isoform 3 (identifier: O15504-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-228: Missing.

    Show »
    Length:195
    Mass (Da):19,312
    Checksum:i90FAD1990293952F
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti391 – 3911D → N.
    Corresponds to variant rs13243961 [ dbSNP | Ensembl ].
    VAR_050572
    Natural varianti392 – 3921K → N.
    Corresponds to variant rs34902971 [ dbSNP | Ensembl ].
    VAR_050573

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 228228Missing in isoform 3. 2 PublicationsVSP_016480Add
    BLAST
    Alternative sequencei204 – 22421LSDVK…FGSSQ → KCLWKIYTHLSPKIYGPDCA L in isoform 2. 2 PublicationsVSP_016481Add
    BLAST
    Alternative sequencei225 – 423199Missing in isoform 2. 2 PublicationsVSP_016482Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U97198 mRNA. Translation: AAC33794.1.
    BT007409 mRNA. Translation: AAP36077.1.
    AK298183 mRNA. Translation: BAG60454.1.
    CH236948 Genomic DNA. Translation: EAL24260.1.
    BC005327 mRNA. Translation: AAH05327.1.
    BC039333 mRNA. Translation: AAH39333.1.
    CCDSiCCDS5379.1. [O15504-1]
    RefSeqiNP_031368.1. NM_007342.2. [O15504-1]
    UniGeneiHs.408241.

    Genome annotation databases

    EnsembliENST00000258742; ENSP00000258742; ENSG00000136243. [O15504-1]
    ENST00000438012; ENSP00000415511; ENSG00000136243. [O15504-2]
    GeneIDi11097.
    KEGGihsa:11097.
    UCSCiuc003svu.3. human. [O15504-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U97198 mRNA. Translation: AAC33794.1 .
    BT007409 mRNA. Translation: AAP36077.1 .
    AK298183 mRNA. Translation: BAG60454.1 .
    CH236948 Genomic DNA. Translation: EAL24260.1 .
    BC005327 mRNA. Translation: AAH05327.1 .
    BC039333 mRNA. Translation: AAH39333.1 .
    CCDSi CCDS5379.1. [O15504-1 ]
    RefSeqi NP_031368.1. NM_007342.2. [O15504-1 ]
    UniGenei Hs.408241.

    3D structure databases

    ProteinModelPortali O15504.
    SMRi O15504. Positions 1-26.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116278. 9 interactions.
    IntActi O15504. 6 interactions.
    MINTi MINT-4786853.
    STRINGi 9606.ENSP00000258742.

    PTM databases

    PhosphoSitei O15504.

    Proteomic databases

    MaxQBi O15504.
    PaxDbi O15504.
    PRIDEi O15504.

    Protocols and materials databases

    DNASUi 11097.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000258742 ; ENSP00000258742 ; ENSG00000136243 . [O15504-1 ]
    ENST00000438012 ; ENSP00000415511 ; ENSG00000136243 . [O15504-2 ]
    GeneIDi 11097.
    KEGGi hsa:11097.
    UCSCi uc003svu.3. human. [O15504-1 ]

    Organism-specific databases

    CTDi 11097.
    GeneCardsi GC07P023222.
    HGNCi HGNC:17010. NUPL2.
    HPAi HPA049036.
    HPA057251.
    neXtProti NX_O15504.
    PharmGKBi PA134990469.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG69917.
    HOGENOMi HOG000113895.
    HOVERGENi HBG082070.
    InParanoidi O15504.
    KOi K14321.
    OrthoDBi EOG70ZZQ7.
    PhylomeDBi O15504.
    TreeFami TF106503.

    Enzyme and pathway databases

    Reactomei REACT_115831. ISG15 antiviral mechanism.
    REACT_163931. Nuclear Pore Complex (NPC) Disassembly.
    REACT_6190. Rev-mediated nuclear export of HIV RNA.
    REACT_6804. Regulation of Glucokinase by Glucokinase Regulatory Protein.
    REACT_7991. Vpr-mediated nuclear import of PICs.
    REACT_9395. Nuclear import of Rev protein.

    Miscellaneous databases

    ChiTaRSi NUPL2. human.
    GeneWikii NUPL2.
    GenomeRNAii 11097.
    NextBioi 42186.
    PROi O15504.

    Gene expression databases

    ArrayExpressi O15504.
    Bgeei O15504.
    CleanExi HS_NUPL2.
    Genevestigatori O15504.

    Family and domain databases

    InterProi IPR000571. Znf_CCCH.
    [Graphical view ]
    PROSITEi PS50103. ZF_C3H1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Refined mapping of a gene for autosomal dominant progressive sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea."
      Van Laer L., Van Camp G., van Zuylen D., Green E.D., Verstreken M., Schatteman I., Van de Heyning P., Balemans W., Coucke P., Greinwald J.H., Smith R.J.H., Huizing E., Willems P.
      Eur. J. Hum. Genet. 5:397-405(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    4. "Human chromosome 7: DNA sequence and biology."
      Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
      , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
      Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
      Tissue: Testis and Urinary bladder.
    6. "The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human."
      Katahira J., Straesser K., Podtelejnikov A., Mann M., Jung J.U., Hurt E.
      EMBO J. 18:2593-2609(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH NXF1.
    7. "The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p."
      Strahm Y., Fahrenkrog B., Zenklusen D., Rychner E., Kantor J., Rosbach M., Stutz F.
      EMBO J. 18:5761-5777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    8. "A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1."
      Farjot G., Sergeant A., Mikaelian I.
      J. Biol. Chem. 274:17309-17317(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, GLYCOSYLATION, TISSUE SPECIFICITY, INTERACTION WITH XPO1 AND HIV-1 VIRUS REV PROTEIN.
    9. "Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1."
      Le Rouzic E., Mousnier A., Rustum C., Stutz F., Hallberg E., Dargemont C., Benichou S.
      J. Biol. Chem. 277:45091-45098(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, INTERACTION WITH HIV-1 VIRUS VPR PROTEIN.
    10. "Interaction between the shuttling mRNA export factor Gle1 and the nucleoporin hCG1: a conserved mechanism in the export of Hsp70 mRNA."
      Kendirgi F., Rexer D.J., Alcazar-Roman A.R., Onishko H.M., Wente S.R.
      Mol. Biol. Cell 16:4304-4315(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH GLE1.
    11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-106, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.

    Entry informationi

    Entry nameiNUPL2_HUMAN
    AccessioniPrimary (citable) accession number: O15504
    Secondary accession number(s): A4D143
    , B4DP42, Q49AE7, Q9BS49
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 6, 2005
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 108 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3