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Protein

Testis-specific protein TEX28

Gene

TEX28

more
Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-specific protein TEX28
Gene namesi
Name:TEX28
Synonyms:CXorf2
AND
Name:TEX28P1
AND
Name:TEX28P2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:2563. TEX28.
HGNC:33356. TEX28P1.
HGNC:33357. TEX28P2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei336 – 35823HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162405646.

Polymorphism and mutation databases

BioMutaiTEX28.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 410410Testis-specific protein TEX28PRO_0000184594Add
BLAST

Proteomic databases

EPDiO15482.
MaxQBiO15482.
PaxDbiO15482.
PRIDEiO15482.

PTM databases

iPTMnetiO15482.
PhosphoSiteiO15482.

Expressioni

Tissue specificityi

Testis specific.

Gene expression databases

BgeeiO15482.
CleanExiHS_TEX28.
GenevisibleiO15482. HS.

Interactioni

Protein-protein interaction databases

BioGridi107907. 24 interactions.
IntActiO15482. 1 interaction.
MINTiMINT-1435415.
STRINGi9606.ENSP00000358957.

Structurei

3D structure databases

ProteinModelPortaliO15482.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili93 – 12836Sequence analysisAdd
BLAST
Coiled coili185 – 24561Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TEX28 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3850. Eukaryota.
ENOG410Y9KV. LUCA.
GeneTreeiENSGT00390000007639.
HOGENOMiHOG000049258.
HOVERGENiHBG055899.
InParanoidiO15482.
OMAiMAYLSYE.
OrthoDBiEOG7W6WKN.
PhylomeDBiO15482.
TreeFamiTF316292.

Family and domain databases

InterProiIPR017387. Testis-specific_TEX28.
IPR019394. TEX28/TMCC.
[Graphical view]
PfamiPF10267. Tmemb_cc2. 2 hits.
[Graphical view]
PIRSFiPIRSF038100. Testis-specific_TEX28. 1 hit.

Sequencei

Sequence statusi: Complete.

O15482-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLKAEHTRS PSATLPSNVP SCRSLSSSED GPSGPSSLAD GGLAHNLQDS
60 70 80 90 100
VRHRILYLSE QLRVEKASRD GNTVSYLKLV SKADRHQVPH IQQAFEKVNQ
110 120 130 140 150
RASATIAQIE HRLHQCHQQL QELEEGCRPE GLLLMAESDP ANCEPPSEKA
160 170 180 190 200
LLSEPPEPGG EDGPVNLPHA SRPFILESRF QSLQQGTCLE TEDVAQQQNL
210 220 230 240 250
LLQKVKAELE EAKRFHISLQ ESYHSLKERS LTDLQLLLES LQEEKCRQAL
260 270 280 290 300
MEEQVNGRLQ GQLNEIYNLK HNLACSEERM AYLSYERAKE IWEITETFKS
310 320 330 340 350
RISKLEMLQQ VTQLEAAEHL QSRPPQMLFK FLSPRLSLAT VLLVFVSTLC
360 370 380 390 400
ACPSSLISSR LCTCTMLMLI GLGVLAWQRW RAIPATDWQE WVPSRCRLYS
410
KDSGPPADGP
Length:410
Mass (Da):46,131
Last modified:January 1, 1998 - v1
Checksum:i8E455A761D52A660
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93720 mRNA. Translation: AAB71379.1.
Z46936, AC092402 Genomic DNA. Translation: CAI41959.1.
Z68193, AC092402 Genomic DNA. Translation: CAI43243.1.
CH471172 Genomic DNA. Translation: EAW72754.1.
CH471172 Genomic DNA. Translation: EAW72755.1.
BC026183 mRNA. Translation: AAH26183.1.
CCDSiCCDS14744.2.
RefSeqiNP_001192130.1. NM_001205201.1.
NP_001577.1. NM_001586.2.
XP_011529422.1. XM_011531120.1.
UniGeneiHs.672606.
Hs.738440.

Genome annotation databases

EnsembliENST00000610938; ENSP00000479148; ENSG00000278057.
ENST00000617225; ENSP00000482010; ENSG00000278057.
ENST00000619903; ENSP00000478834; ENSG00000278057.
GeneIDi1527.
KEGGihsa:1527.
UCSCiuc033fba.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U93720 mRNA. Translation: AAB71379.1.
Z46936, AC092402 Genomic DNA. Translation: CAI41959.1.
Z68193, AC092402 Genomic DNA. Translation: CAI43243.1.
CH471172 Genomic DNA. Translation: EAW72754.1.
CH471172 Genomic DNA. Translation: EAW72755.1.
BC026183 mRNA. Translation: AAH26183.1.
CCDSiCCDS14744.2.
RefSeqiNP_001192130.1. NM_001205201.1.
NP_001577.1. NM_001586.2.
XP_011529422.1. XM_011531120.1.
UniGeneiHs.672606.
Hs.738440.

3D structure databases

ProteinModelPortaliO15482.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi107907. 24 interactions.
IntActiO15482. 1 interaction.
MINTiMINT-1435415.
STRINGi9606.ENSP00000358957.

PTM databases

iPTMnetiO15482.
PhosphoSiteiO15482.

Polymorphism and mutation databases

BioMutaiTEX28.

Proteomic databases

EPDiO15482.
MaxQBiO15482.
PaxDbiO15482.
PRIDEiO15482.

Protocols and materials databases

DNASUi1527.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000610938; ENSP00000479148; ENSG00000278057.
ENST00000617225; ENSP00000482010; ENSG00000278057.
ENST00000619903; ENSP00000478834; ENSG00000278057.
GeneIDi1527.
KEGGihsa:1527.
UCSCiuc033fba.2. human.

Organism-specific databases

CTDi1527.
GeneCardsiTEX28.
TEX28P1.
TEX28P2.
HGNCiHGNC:2563. TEX28.
HGNC:33356. TEX28P1.
HGNC:33357. TEX28P2.
MIMi300092. gene.
neXtProtiNX_O15482.
PharmGKBiPA162405646.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3850. Eukaryota.
ENOG410Y9KV. LUCA.
GeneTreeiENSGT00390000007639.
HOGENOMiHOG000049258.
HOVERGENiHBG055899.
InParanoidiO15482.
OMAiMAYLSYE.
OrthoDBiEOG7W6WKN.
PhylomeDBiO15482.
TreeFamiTF316292.

Miscellaneous databases

GenomeRNAii1527.
PROiO15482.
SOURCEiSearch...

Gene expression databases

BgeeiO15482.
CleanExiHS_TEX28.
GenevisibleiO15482. HS.

Family and domain databases

InterProiIPR017387. Testis-specific_TEX28.
IPR019394. TEX28/TMCC.
[Graphical view]
PfamiPF10267. Tmemb_cc2. 2 hits.
[Graphical view]
PIRSFiPIRSF038100. Testis-specific_TEX28. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a gene within the tandem array of red and green color pigment genes."
    Hanna M.C., Platts J.T., Kirkness E.F.
    Genomics 43:384-386(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Testis.
  2. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiTEX28_HUMAN
AccessioniPrimary (citable) accession number: O15482
Secondary accession number(s): B1B1E8, D3DWW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.