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O15385

- O15385_HUMAN

UniProt

O15385 - O15385_HUMAN

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Protein
Submitted name: NAD (H)-specific isocitrate dehydrogenase gamma subunit
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NAD+) activity Source: UniProtKB
  3. magnesium ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
NAD (H)-specific isocitrate dehydrogenase gamma subunitImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: HPA
  2. nucleus Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiO15385.

Expressioni

Gene expression databases

ArrayExpressiO15385.
BgeeiO15385.

Structurei

3D structure databases

ProteinModelPortaliO15385.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000021113.
HOVERGENiHBG052080.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

O15385-1 [UniParc]FASTAAdd to Basket

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KSLRIAEYAF KLAQESGRKK VTAVHKANIM KLGDGLFLQC CREVAARYPQ    50
ITFENMIVDN TTMQLVSRPQ QFDVMVMPNL YGNIVNNVCA GLVGGPGLVA 100
GANYGHVYAV FETATRNTGK SIANKNIANP TATLLASCMM LDHLKLHSYA 150
TSIRKAVLAS MDNENGLVCA EPACVLQMHT PDIGGQGTTS EAIQDVIRHI 200
RVINGRAVEA 210
Length:210
Mass (Da):22,706
Last modified:January 1, 1998 - v1
Checksum:i2F83A837F5A59B1B
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U69269 mRNA. Translation: AAB70116.1.
UniGeneiHs.410197.

Genome annotation databases

UCSCiuc004fiu.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U69269 mRNA. Translation: AAB70116.1 .
UniGenei Hs.410197.

3D structure databases

ProteinModelPortali O15385.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi O15385.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc004fiu.3. human.

Phylogenomic databases

HOGENOMi HOG000021113.
HOVERGENi HBG052080.

Gene expression databases

ArrayExpressi O15385.
Bgeei O15385.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse."
    Brenner V., Nyakatura G., Rosenthal A., Platzer M.
    Genomics 44:8-14(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Soares liver spleen 1NFLSImported.

Entry informationi

Entry nameiO15385_HUMAN
AccessioniPrimary (citable) accession number: O15385
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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