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O15320

- CTGE5_HUMAN

UniProt

O15320 - CTGE5_HUMAN

Protein

cTAGE family member 5

Gene

CTAGE5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 122 (01 Oct 2014)
      Sequence version 4 (02 Nov 2010)
      Previous versions | rss
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    Functioni

    Tumor-associated antigen.

    GO - Molecular functioni

    1. enzyme activator activity Source: ProtInc

    GO - Biological processi

    1. positive regulation of catalytic activity Source: GOC

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    cTAGE family member 5
    Short name:
    Protein cTAGE-5
    Alternative name(s):
    Meningioma-expressed antigen 6/11
    Gene namesi
    Name:CTAGE5
    Synonyms:MEA11, MEA6, MGEA11, MGEA6
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 14

    Organism-specific databases

    HGNCiHGNC:7057. CTAGE5.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: UniProtKB

    Pathology & Biotechi

    Involvement in diseasei

    Autoantibodies against CTAGE5 are present in several cancer types, including benign meningioma and cutaneous T-cell lymphoma (CTCL).

    Organism-specific databases

    PharmGKBiPA30788.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 804804cTAGE family member 5PRO_0000189541Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei536 – 5361PhosphoserineBy similarity
    Modified residuei548 – 5481PhosphoserineBy similarity
    Modified residuei678 – 6781PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiO15320.
    PaxDbiO15320.
    PRIDEiO15320.

    PTM databases

    PhosphoSiteiO15320.

    Expressioni

    Tissue specificityi

    Isoform 5A is expressed only in testis (at the protein level). Other isoforms are expressed in several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B are expressed in cutaneous T-cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A, is expressed in head and neck squamous cell carcinoma.

    Gene expression databases

    BgeeiO15320.
    CleanExiHS_CTAGE5.
    GenevestigatoriO15320.

    Organism-specific databases

    HPAiHPA000387.
    HPA000922.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    ABL1P005191EBI-1050253,EBI-375543

    Protein-protein interaction databases

    BioGridi110409. 4 interactions.
    IntActiO15320. 5 interactions.
    MINTiMINT-4526262.

    Structurei

    3D structure databases

    ProteinModelPortaliO15320.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili87 – 273187Sequence AnalysisAdd
    BLAST
    Coiled coili321 – 501181Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi502 – 804303Pro-richAdd
    BLAST
    Compositional biasi553 – 5586Poly-Gly

    Sequence similaritiesi

    Belongs to the cTAGE family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG133684.
    HOVERGENiHBG051216.
    InParanoidiO15320.
    OrthoDBiEOG74TWXQ.
    PhylomeDBiO15320.
    TreeFamiTF333137.

    Sequences (10)i

    Sequence statusi: Complete.

    This entry describes 10 isoformsi produced by alternative splicing. Align

    Isoform MEA6 (identifier: O15320-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEEPGVTPQP YLGLLLEELR RVVAALPEGM RPDSNLYGFP WELVICAAVV    50
    GFFAVLFFLW RSFRSVRSRL YVGREKKLAL MLSGLIEEKS KLLEKFSLVQ 100
    KEYEGYEVES SLKDASFEKE ATEAQSLEAT CEKLNRSNSE LEDEILCLEK 150
    ELKEEKSKHS EQDELMADIS KRIQSLEDES KSLKSQVAEA KMTFKIFQMN 200
    EERLKIAIKD ALNENSQLQE SQKQLLQEAE VWKEQVSELN KQKVTFEDSK 250
    VHAEQVLNDK ESHIKTLTER LLKMKDWAAM LGEDITDDDN LELEMNSESE 300
    NGAYLDNPPK GALKKLIHAA KLNASLKTLE GERNQIYIQL SEVDKTKEEL 350
    TEHIKNLQTE QASLQSENTH FENENQKLQQ KLKVMTELYQ ENEMKLHRKL 400
    TVEENYRLEK EEKLSKVDEK ISHATEELET YRKRAKDLEE ELERTIHSYQ 450
    GQIISHEKKA HDNWLAARNA ERNLNDLRKE NAHNRQKLTE TELKFELLEK 500
    DPYALDVPNT AFGREHSPYG PSPLGWPSSE TRAFLSPPTL LEGPLRLSPL 550
    LPGGGGRGSR GPGNPLDHQI TNERGESSCD RLTDPHRAPS DTGSLSPPWD 600
    QDRRMMFPPP GQSYPDSALP PQRQDRFCSN SGRLSGPAEL RSFNMPSLDK 650
    MDGSMPSEME SSRNDTKDDL GNLNVPDSSL PAENEATGPG FVPPPLAPIR 700
    GPLFPVDARG PFLRRGPPFP PPPPGAMFGA SRDYFPPGDF PGPPPAPFAM 750
    RNVYPPRGFP PYLPPRPGFF PPPPHSEGRS EFPSGLIPPS NEPATEHPEP 800
    QQET 804
    Length:804
    Mass (Da):90,996
    Last modified:November 2, 2010 - v4
    Checksum:iEB2CAC59C4ED7867
    GO
    Isoform MEA11 (identifier: O15320-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         514-556: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:761
    Mass (Da):86,532
    Checksum:iB101FD49659A2F30
    GO
    Isoform 5A (identifier: O15320-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-29: Missing.

    Show »
    Length:775
    Mass (Da):87,837
    Checksum:i46C11CD859A408FF
    GO
    Isoform 5B (identifier: O15320-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         750-771: MRNVYPPRGFPPYLPPRPGFFP → SARSPPGAGAPASGRGLGGPQK
         772-804: Missing.

    Show »
    Length:771
    Mass (Da):86,811
    Checksum:i2E5D4546606E6EC3
    GO
    Isoform 6 (identifier: O15320-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         128-128: E → EVENQM

    Show »
    Length:809
    Mass (Da):91,598
    Checksum:i93E6E1B2E908306B
    GO
    Isoform 7 (identifier: O15320-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-80: Missing.
         128-128: E → EVENQM

    Show »
    Length:729
    Mass (Da):82,443
    Checksum:i31620F247C9CF9A1
    GO
    Isoform 8 (identifier: O15320-7) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-29: Missing.
         515-557: Missing.

    Show »
    Length:732
    Mass (Da):83,373
    Checksum:i3A7C4AC2B3D65396
    GO
    Isoform 9 (identifier: O15320-8) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-80: Missing.

    Show »
    Length:724
    Mass (Da):81,841
    Checksum:iAFE56681C351F234
    GO
    Isoform 10 (identifier: O15320-9) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         3-21: EPGVTPQPYLGLLLEELRR → LKSPEEE
         103-128: Missing.
         647-717: Missing.
         725-747: Missing.

    Show »
    Length:672
    Mass (Da):76,880
    Checksum:iCA742CB43201E4FE
    GO
    Isoform 11 (identifier: O15320-10) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         3-21: EPGVTPQPYLGLLLEELRR → LKSPEEE

    Note: Gene prediction based on EST data.

    Show »
    Length:792
    Mass (Da):89,647
    Checksum:i0C9C6951D420A590
    GO

    Sequence cautioni

    The sequence AAB86589.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti90 – 901S → N in CAE45997. (PubMed:17974005)Curated
    Sequence conflicti145 – 1451I → M in CAE45997. (PubMed:17974005)Curated
    Sequence conflicti195 – 1951K → Q in AAB86593. (PubMed:9356211)Curated
    Sequence conflicti195 – 1951K → Q in AAB86589. (PubMed:9356211)Curated
    Sequence conflicti198 – 1981Q → P in AAB86593. (PubMed:9356211)Curated
    Sequence conflicti546 – 5461R → T in AAB86593. (PubMed:9356211)Curated
    Sequence conflicti589 – 5891P → L in AAB86593. (PubMed:9356211)Curated
    Sequence conflicti594 – 5941S → F in AAB86593. (PubMed:9356211)Curated
    Sequence conflicti604 – 6041R → M in AAN77610. (PubMed:12839582)Curated
    Sequence conflicti776 – 7761S → F in AAN77610. (PubMed:12839582)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti6 – 61V → A.2 Publications
    Corresponds to variant rs7140561 [ dbSNP | Ensembl ].
    VAR_047889
    Natural varianti11 – 111Y → D.1 Publication
    Corresponds to variant rs17855895 [ dbSNP | Ensembl ].
    VAR_047890
    Natural varianti205 – 2051K → N.1 Publication
    Corresponds to variant rs17855896 [ dbSNP | Ensembl ].
    VAR_047891
    Natural varianti250 – 2501K → E.
    Corresponds to variant rs10162564 [ dbSNP | Ensembl ].
    VAR_047892
    Natural varianti360 – 3601E → Q.4 Publications
    Corresponds to variant rs1950952 [ dbSNP | Ensembl ].
    VAR_047893
    Natural varianti375 – 3751N → S.
    Corresponds to variant rs17109109 [ dbSNP | Ensembl ].
    VAR_047894
    Natural varianti699 – 6991I → V.3 Publications
    Corresponds to variant rs1140952 [ dbSNP | Ensembl ].
    VAR_047895
    Natural varianti738 – 7381G → R.3 Publications
    Corresponds to variant rs1060878 [ dbSNP | Ensembl ].
    VAR_047896

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 8080Missing in isoform 7 and isoform 9. 2 PublicationsVSP_035961Add
    BLAST
    Alternative sequencei1 – 2929Missing in isoform 5A and isoform 8. 2 PublicationsVSP_012545Add
    BLAST
    Alternative sequencei3 – 2119EPGVT…EELRR → LKSPEEE in isoform 10 and isoform 11. 1 PublicationVSP_047234Add
    BLAST
    Alternative sequencei103 – 12826Missing in isoform 10. 1 PublicationVSP_047235Add
    BLAST
    Alternative sequencei128 – 1281E → EVENQM in isoform 6 and isoform 7. 1 PublicationVSP_035962
    Alternative sequencei514 – 55643Missing in isoform MEA11. 1 PublicationVSP_004322Add
    BLAST
    Alternative sequencei515 – 55743Missing in isoform 8. 1 PublicationVSP_035963Add
    BLAST
    Alternative sequencei647 – 71771Missing in isoform 10. 1 PublicationVSP_047236Add
    BLAST
    Alternative sequencei725 – 74723Missing in isoform 10. 1 PublicationVSP_047237Add
    BLAST
    Alternative sequencei750 – 77122MRNVY…PGFFP → SARSPPGAGAPASGRGLGGP QK in isoform 5B. 1 PublicationVSP_012546Add
    BLAST
    Alternative sequencei772 – 80433Missing in isoform 5B. 1 PublicationVSP_012547Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U73682 mRNA. Translation: AAB86589.1. Different initiation.
    U94780 mRNA. Translation: AAB86593.1.
    AF338233 mRNA. Translation: AAN77610.1.
    AF338234 mRNA. Translation: AAN77611.1.
    AK091252 mRNA. Translation: BAG52318.1.
    AK298935 mRNA. Translation: BAG61038.1.
    BX640994 mRNA. Translation: CAE45997.1.
    AL132639 Genomic DNA. No translation available.
    AL157791 Genomic DNA. No translation available.
    CH471078 Genomic DNA. Translation: EAW65808.1.
    CH471078 Genomic DNA. Translation: EAW65812.1.
    CH471078 Genomic DNA. Translation: EAW65813.1.
    CH471078 Genomic DNA. Translation: EAW65814.1.
    BC051363 mRNA. Translation: AAH51363.2.
    BC064355 mRNA. Translation: AAH64355.1.
    CCDSiCCDS58316.1. [O15320-5]
    CCDS58317.1. [O15320-6]
    CCDS9673.1. [O15320-10]
    CCDS9674.1. [O15320-1]
    CCDS9675.1. [O15320-2]
    CCDS9676.1. [O15320-3]
    RefSeqiNP_001234917.1. NM_001247988.1. [O15320-7]
    NP_001234918.1. NM_001247989.1. [O15320-5]
    NP_001234919.1. NM_001247990.1. [O15320-6]
    NP_005921.2. NM_005930.3. [O15320-1]
    NP_976229.1. NM_203354.2. [O15320-10]
    NP_976231.1. NM_203356.2. [O15320-3]
    XP_006720211.1. XM_006720148.1. [O15320-3]
    UniGeneiHs.509200.
    Hs.540038.
    Hs.741763.

    Genome annotation databases

    EnsembliENST00000280083; ENSP00000280083; ENSG00000150527. [O15320-1]
    ENST00000341502; ENSP00000339286; ENSG00000150527. [O15320-4]
    ENST00000341749; ENSP00000343897; ENSG00000150527. [O15320-10]
    ENST00000348007; ENSP00000343912; ENSG00000150527. [O15320-2]
    ENST00000396158; ENSP00000379462; ENSG00000150527. [O15320-5]
    ENST00000396165; ENSP00000379468; ENSG00000150527. [O15320-3]
    ENST00000553352; ENSP00000450449; ENSG00000150527. [O15320-3]
    ENST00000556148; ENSP00000452562; ENSG00000150527. [O15320-6]
    ENST00000557038; ENSP00000450869; ENSG00000150527. [O15320-8]
    GeneIDi4253.
    KEGGihsa:4253.
    UCSCiuc001wuy.4. human. [O15320-1]
    uc001wuz.4. human.
    uc001wvb.4. human. [O15320-7]
    uc001wvf.4. human. [O15320-6]
    uc001wvh.4. human. [O15320-2]
    uc001wvi.4. human. [O15320-5]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U73682 mRNA. Translation: AAB86589.1 . Different initiation.
    U94780 mRNA. Translation: AAB86593.1 .
    AF338233 mRNA. Translation: AAN77610.1 .
    AF338234 mRNA. Translation: AAN77611.1 .
    AK091252 mRNA. Translation: BAG52318.1 .
    AK298935 mRNA. Translation: BAG61038.1 .
    BX640994 mRNA. Translation: CAE45997.1 .
    AL132639 Genomic DNA. No translation available.
    AL157791 Genomic DNA. No translation available.
    CH471078 Genomic DNA. Translation: EAW65808.1 .
    CH471078 Genomic DNA. Translation: EAW65812.1 .
    CH471078 Genomic DNA. Translation: EAW65813.1 .
    CH471078 Genomic DNA. Translation: EAW65814.1 .
    BC051363 mRNA. Translation: AAH51363.2 .
    BC064355 mRNA. Translation: AAH64355.1 .
    CCDSi CCDS58316.1. [O15320-5 ]
    CCDS58317.1. [O15320-6 ]
    CCDS9673.1. [O15320-10 ]
    CCDS9674.1. [O15320-1 ]
    CCDS9675.1. [O15320-2 ]
    CCDS9676.1. [O15320-3 ]
    RefSeqi NP_001234917.1. NM_001247988.1. [O15320-7 ]
    NP_001234918.1. NM_001247989.1. [O15320-5 ]
    NP_001234919.1. NM_001247990.1. [O15320-6 ]
    NP_005921.2. NM_005930.3. [O15320-1 ]
    NP_976229.1. NM_203354.2. [O15320-10 ]
    NP_976231.1. NM_203356.2. [O15320-3 ]
    XP_006720211.1. XM_006720148.1. [O15320-3 ]
    UniGenei Hs.509200.
    Hs.540038.
    Hs.741763.

    3D structure databases

    ProteinModelPortali O15320.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 110409. 4 interactions.
    IntActi O15320. 5 interactions.
    MINTi MINT-4526262.

    PTM databases

    PhosphoSitei O15320.

    Proteomic databases

    MaxQBi O15320.
    PaxDbi O15320.
    PRIDEi O15320.

    Protocols and materials databases

    DNASUi 4253.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000280083 ; ENSP00000280083 ; ENSG00000150527 . [O15320-1 ]
    ENST00000341502 ; ENSP00000339286 ; ENSG00000150527 . [O15320-4 ]
    ENST00000341749 ; ENSP00000343897 ; ENSG00000150527 . [O15320-10 ]
    ENST00000348007 ; ENSP00000343912 ; ENSG00000150527 . [O15320-2 ]
    ENST00000396158 ; ENSP00000379462 ; ENSG00000150527 . [O15320-5 ]
    ENST00000396165 ; ENSP00000379468 ; ENSG00000150527 . [O15320-3 ]
    ENST00000553352 ; ENSP00000450449 ; ENSG00000150527 . [O15320-3 ]
    ENST00000556148 ; ENSP00000452562 ; ENSG00000150527 . [O15320-6 ]
    ENST00000557038 ; ENSP00000450869 ; ENSG00000150527 . [O15320-8 ]
    GeneIDi 4253.
    KEGGi hsa:4253.
    UCSCi uc001wuy.4. human. [O15320-1 ]
    uc001wuz.4. human.
    uc001wvb.4. human. [O15320-7 ]
    uc001wvf.4. human. [O15320-6 ]
    uc001wvh.4. human. [O15320-2 ]
    uc001wvi.4. human. [O15320-5 ]

    Organism-specific databases

    CTDi 4253.
    GeneCardsi GC14P039734.
    H-InvDB HIX0021193.
    HGNCi HGNC:7057. CTAGE5.
    HPAi HPA000387.
    HPA000922.
    MIMi 602132. gene.
    neXtProti NX_O15320.
    PharmGKBi PA30788.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG133684.
    HOVERGENi HBG051216.
    InParanoidi O15320.
    OrthoDBi EOG74TWXQ.
    PhylomeDBi O15320.
    TreeFami TF333137.

    Miscellaneous databases

    GeneWikii CTAGE5.
    GenomeRNAii 4253.
    NextBioi 16763.
    PROi O15320.
    SOURCEi Search...

    Gene expression databases

    Bgeei O15320.
    CleanExi HS_CTAGE5.
    Genevestigatori O15320.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "cDNA cloning and chromosomal mapping of a predicted coiled-coil proline-rich protein immunogenic in meningioma patients."
      Heckel D., Brass N., Fischer U., Blin N., Steudel I., Tuereci O., Fackler O., Zang K.D., Meese E.
      Hum. Mol. Genet. 6:2031-2041(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS MEA6 AND MEA11), VARIANTS ALA-6; GLN-360; VAL-699 AND ARG-738.
      Tissue: Meningioma.
    2. "cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing."
      Usener D., Schadendorf D., Koch J., Duebel S., Eichmueller S.
      J. Invest. Dermatol. 121:198-206(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 5A AND 5B), VARIANTS ALA-6; GLN-360 AND ARG-738.
      Tissue: Testis.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 8 AND 10), VARIANTS GLN-360 AND VAL-699.
      Tissue: Teratocarcinoma and Tongue.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 9), VARIANTS GLN-360 AND ARG-738.
      Tissue: Salivary gland.
    5. "The DNA sequence and analysis of human chromosome 14."
      Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
      , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
      Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 6 AND 7), VARIANTS ASP-11; ASN-205 AND VAL-699.
      Tissue: B-cell and Skin.

    Entry informationi

    Entry nameiCTGE5_HUMAN
    AccessioniPrimary (citable) accession number: O15320
    Secondary accession number(s): B3KRA6
    , B4DQS6, D3DSA6, G3XAC5, O00169, Q6MZN2, Q6P2R8, Q86TF6, Q8IX92, Q8IX93
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 27, 2001
    Last sequence update: November 2, 2010
    Last modified: October 1, 2014
    This is version 122 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 14
      Human chromosome 14: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3