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O15182

- CETN3_HUMAN

UniProt

O15182 - CETN3_HUMAN

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Protein
Centrin-3
Gene
CETN3, CEN3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Plays a fundamental role in microtubule-organizing center structure and function.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi38 – 49121 Reviewed prediction
Add
BLAST
Calcium bindingi147 – 158122 Inferred
Add
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. centrosome cycle Source: ProtInc
  2. mitotic nuclear division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Centrin-3
Gene namesi
Name:CETN3
Synonyms:CEN3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:1868. CETN3.

Subcellular locationi

Cytoplasmcytoskeletonmicrotubule organizing centercentrosome
Note: Centrosome of interphase and mitotic cells.

GO - Cellular componenti

  1. centriole Source: ProtInc
  2. centrosome Source: UniProtKB
  3. cytoplasm Source: HPA
  4. intermediate filament cytoskeleton Source: HPA
  5. photoreceptor connecting cilium Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26421.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 167167Centrin-3
PRO_0000073563Add
BLAST

Proteomic databases

MaxQBiO15182.
PaxDbiO15182.
PRIDEiO15182.

PTM databases

PhosphoSiteiO15182.

Expressioni

Gene expression databases

ArrayExpressiO15182.
Bgeei