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Protein

Kinesin-like protein KIF3B

Gene

KIF3B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi96 – 1038ATP

GO - Molecular functioni

  1. ATPase activity Source: GO_Central
  2. ATP binding Source: UniProtKB-KW
  3. ATP-dependent microtubule motor activity, plus-end-directed Source: ProtInc
  4. microtubule motor activity Source: GO_Central
  5. Rho GTPase binding Source: BHF-UCL

GO - Biological processi

  1. anterograde axon cargo transport Source: ProtInc
  2. antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
  3. blood coagulation Source: Reactome
  4. cytoskeleton-dependent intracellular transport Source: GO_Central
  5. determination of left/right symmetry Source: ProtInc
  6. membrane organization Source: Reactome
  7. metabolic process Source: GOC
  8. microtubule-based movement Source: GO_Central
  9. mitotic centrosome separation Source: BHF-UCL
  10. mitotic spindle assembly Source: BHF-UCL
  11. mitotic spindle organization Source: BHF-UCL
  12. organelle organization Source: Reactome
  13. plus-end-directed vesicle transport along microtubule Source: BHF-UCL
  14. positive regulation of cytokinesis Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Motor protein

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_121399. MHC class II antigen presentation.
REACT_147867. Translocation of GLUT4 to the plasma membrane.
REACT_25201. Kinesins.
REACT_268024. Intraflagellar transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like protein KIF3B
Alternative name(s):
HH0048
Microtubule plus end-directed kinesin motor 3B
Cleaved into the following chain:
Gene namesi
Name:KIF3B
Synonyms:KIAA0359
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:6320. KIF3B.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: BHF-UCL
  2. ciliary tip Source: Reactome
  3. cytosol Source: Reactome
  4. extracellular vesicular exosome Source: UniProtKB
  5. intraciliary transport particle Source: Ensembl
  6. kinesin II complex Source: BHF-UCL
  7. membrane Source: UniProtKB
  8. microtubule Source: UniProtKB-KW
  9. microtubule cytoskeleton Source: BHF-UCL
  10. midbody Source: Ensembl
  11. plus-end kinesin complex Source: ProtInc
  12. primary cilium Source: Reactome
  13. spindle Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30103.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 747747Kinesin-like protein KIF3BPRO_0000424495Add
BLAST
Initiator methioninei1 – 11Removed; alternate1 Publication
Chaini2 – 747746Kinesin-like protein KIF3B, N-terminally processedPRO_0000125395Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication
Modified residuei2 – 21N-acetylserine; in Kinesin-like protein KIF3B, N-terminally processed1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiO15066.
PaxDbiO15066.
PeptideAtlasiO15066.
PRIDEiO15066.

PTM databases

PhosphoSiteiO15066.

Expressioni

Gene expression databases

BgeeiO15066.
CleanExiHS_KIF3B.
GenevestigatoriO15066.

Organism-specific databases

HPAiHPA007119.

Interactioni

Subunit structurei

Heterodimer of KIF3A and KIF3B. Interacts directly with IFT20 (By similarity). Interacts with the SMC3 subunit of the cohesin complex.By similarity2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
ARHGEF10O150133EBI-3931791,EBI-2515636
KIFAP3Q928452EBI-3931791,EBI-954040

Protein-protein interaction databases

BioGridi114772. 13 interactions.
IntActiO15066. 4 interactions.
MINTiMINT-1185610.
STRINGi9606.ENSP00000364864.

Structurei

Secondary structure

1
747
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi11 – 166Combined sources
Helixi21 – 255Combined sources
Beta strandi32 – 354Combined sources
Turni36 – 394Combined sources
Beta strandi40 – 434Combined sources
Turni49 – 513Combined sources
Beta strandi55 – 584Combined sources
Beta strandi60 – 634Combined sources
Helixi69 – 757Combined sources
Helixi77 – 859Combined sources
Beta strandi90 – 978Combined sources
Helixi102 – 1065Combined sources
Helixi113 – 1153Combined sources
Helixi118 – 13114Combined sources
Beta strandi137 – 14812Combined sources
Beta strandi151 – 1544Combined sources
Beta strandi166 – 1694Combined sources
Turni170 – 1723Combined sources
Beta strandi173 – 1764Combined sources
Helixi187 – 20115Combined sources
Turni202 – 2043Combined sources
Helixi208 – 2136Combined sources
Beta strandi215 – 22713Combined sources
Beta strandi235 – 24511Combined sources
Beta strandi261 – 2644Combined sources
Helixi265 – 2673Combined sources
Helixi270 – 28314Combined sources
Helixi292 – 2943Combined sources
Helixi296 – 3005Combined sources
Turni301 – 3066Combined sources
Beta strandi307 – 31711Combined sources
Helixi321 – 3233Combined sources
Helixi324 – 33714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B6UX-ray1.80A/B6-359[»]
ProteinModelPortaliO15066.
SMRiO15066. Positions 7-358.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO15066.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 340332Kinesin motorPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni580 – 747168GlobularAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili346 – 579234Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi386 – 3938Poly-Gly
Compositional biasi394 – 40613Poly-GluAdd
BLAST
Compositional biasi723 – 7308Poly-Ser

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.PROSITE-ProRule annotation
Contains 1 kinesin motor domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiCOG5059.
GeneTreeiENSGT00770000120453.
HOGENOMiHOG000116164.
HOVERGENiHBG052255.
InParanoidiO15066.
KOiK10394.
OMAiDNQQMMK.
OrthoDBiEOG7WX086.
PhylomeDBiO15066.
TreeFamiTF105223.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: O15066-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSKLKSSESV RVVVRCRPMN GKEKAASYDK VVDVDVKLGQ VSVKNPKGTA
60 70 80 90 100
HEMPKTFTFD AVYDWNAKQF ELYDETFRPL VDSVLQGFNG TIFAYGQTGT
110 120 130 140 150
GKTYTMEGIR GDPEKRGVIP NSFDHIFTHI SRSQNQQYLV RASYLEIYQE
160 170 180 190 200
EIRDLLSKDQ TKRLELKERP DTGVYVKDLS SFVTKSVKEI EHVMNVGNQN
210 220 230 240 250
RSVGATNMNE HSSRSHAIFV ITIECSEVGL DGENHIRVGK LNLVDLAGSE
260 270 280 290 300
RQAKTGAQGE RLKEATKINL SLSALGNVIS ALVDGKSTHI PYRDSKLTRL
310 320 330 340 350
LQDSLGGNAK TVMVANVGPA SYNVEETLTT LRYANRAKNI KNKPRVNEDP
360 370 380 390 400
KDALLREFQE EIARLKAQLE KRSIGRRKRR EKRREGGGSG GGGEEEEEEG
410 420 430 440 450
EEGEEEGDDK DDYWREQQEK LEIEKRAIVE DHSLVAEEKM RLLKEKEKKM
460 470 480 490 500
EDLRREKDAA EMLGAKIKAM ESKLLVGGKN IVDHTNEQQK ILEQKRQEIA
510 520 530 540 550
EQKRREREIQ QQMESRDEET LELKETYSSL QQEVDIKTKK LKKLFSKLQA
560 570 580 590 600
VKAEIHDLQE EHIKERQELE QTQNELTREL KLKHLIIENF IPLEEKSKIM
610 620 630 640 650
NRAFFDEEED HWKLHPITRL ENQQMMKRPV SAVGYKRPLS QHARMSMMIR
660 670 680 690 700
PEARYRAENI VLLELDMPSR TTRDYEGPAI APKVQAALDA ALQDEDEIQV
710 720 730 740
DASSFESTAN KKSKARPKSG RKSGSSSSSS GTPASQLYPQ SRGLVPK
Length:747
Mass (Da):85,125
Last modified:December 31, 1997 - v1
Checksum:i97FA4573AFA87023
GO
Isoform 2 (identifier: O15066-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-312: Missing.
     375-436: Missing.

Note: No experimental confirmation available.

Show »
Length:373
Mass (Da):43,269
Checksum:i1B9F29FF59BA9DD2
GO

Sequence cautioni

The sequence BAA20815.2 differs from that shown. Reason: Erroneous initiation. Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 312312Missing in isoform 2. 1 PublicationVSP_056489Add
BLAST
Alternative sequencei375 – 43662Missing in isoform 2. 1 PublicationVSP_056490Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002357 mRNA. Translation: BAA20815.2. Different initiation.
AK299877 mRNA. Translation: BAG61727.1.
AL121897 Genomic DNA. Translation: CAC16425.1.
AL354800 Genomic DNA. No translation available.
CH471077 Genomic DNA. Translation: EAW76381.1.
CH471077 Genomic DNA. Translation: EAW76382.1.
BC136310 mRNA. Translation: AAI36311.1.
BC136311 mRNA. Translation: AAI36312.1.
CCDSiCCDS13200.1. [O15066-1]
RefSeqiNP_004789.1. NM_004798.3. [O15066-1]
UniGeneiHs.369670.

Genome annotation databases

EnsembliENST00000375712; ENSP00000364864; ENSG00000101350. [O15066-1]
GeneIDi9371.
KEGGihsa:9371.
UCSCiuc002wxq.3. human. [O15066-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB002357 mRNA. Translation: BAA20815.2. Different initiation.
AK299877 mRNA. Translation: BAG61727.1.
AL121897 Genomic DNA. Translation: CAC16425.1.
AL354800 Genomic DNA. No translation available.
CH471077 Genomic DNA. Translation: EAW76381.1.
CH471077 Genomic DNA. Translation: EAW76382.1.
BC136310 mRNA. Translation: AAI36311.1.
BC136311 mRNA. Translation: AAI36312.1.
CCDSiCCDS13200.1. [O15066-1]
RefSeqiNP_004789.1. NM_004798.3. [O15066-1]
UniGeneiHs.369670.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B6UX-ray1.80A/B6-359[»]
ProteinModelPortaliO15066.
SMRiO15066. Positions 7-358.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114772. 13 interactions.
IntActiO15066. 4 interactions.
MINTiMINT-1185610.
STRINGi9606.ENSP00000364864.

Chemistry

BindingDBiO15066.
ChEMBLiCHEMBL6109.

PTM databases

PhosphoSiteiO15066.

Proteomic databases

MaxQBiO15066.
PaxDbiO15066.
PeptideAtlasiO15066.
PRIDEiO15066.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375712; ENSP00000364864; ENSG00000101350. [O15066-1]
GeneIDi9371.
KEGGihsa:9371.
UCSCiuc002wxq.3. human. [O15066-1]

Organism-specific databases

CTDi9371.
GeneCardsiGC20P030865.
HGNCiHGNC:6320. KIF3B.
HPAiHPA007119.
MIMi603754. gene.
neXtProtiNX_O15066.
PharmGKBiPA30103.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG5059.
GeneTreeiENSGT00770000120453.
HOGENOMiHOG000116164.
HOVERGENiHBG052255.
InParanoidiO15066.
KOiK10394.
OMAiDNQQMMK.
OrthoDBiEOG7WX086.
PhylomeDBiO15066.
TreeFamiTF105223.

Enzyme and pathway databases

ReactomeiREACT_121399. MHC class II antigen presentation.
REACT_147867. Translocation of GLUT4 to the plasma membrane.
REACT_25201. Kinesins.
REACT_268024. Intraflagellar transport.

Miscellaneous databases

ChiTaRSiKIF3B. human.
EvolutionaryTraceiO15066.
GeneWikiiKIF3B.
GenomeRNAii9371.
NextBioi35098.
PROiO15066.
SOURCEiSearch...

Gene expression databases

BgeeiO15066.
CleanExiHS_KIF3B.
GenevestigatoriO15066.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Nakajima D., Ohira M., Seki N., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 4:141-150(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  3. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain and Testis.
  6. "Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide."
    Shimizu K., Shirataki H., Honda T., Minami S., Takai Y.
    J. Biol. Chem. 273:6591-6594(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN A COMPLEX WITH SMC3 AND KIFAP3B.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
  9. "Motor domain of human kinesin family member 3B in complex with ADP."
    Structural genomics consortium (SGC)
    Submitted (JAN-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 6-359IN COMPLEX WITH ADP.

Entry informationi

Entry nameiKIF3B_HUMAN
AccessioniPrimary (citable) accession number: O15066
Secondary accession number(s): B2RMP4, B4DSR5, E1P5M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 1998
Last sequence update: December 31, 1997
Last modified: March 31, 2015
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.