##gff-version 3 O14966 UniProtKB Chain 1 203 . . . ID=PRO_0000121127;Note=Ras-related protein Rab-7L1 O14966 UniProtKB Motif 36 44 . . . Note=Effector region;Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Binding site 14 21 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Binding site 33 39 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Binding site 63 67 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Binding site 125 128 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Binding site 156 157 . . . Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Site 41 42 . . . Note=Cleavage%3B by S.Typhimurium viral protease GtgE O14966 UniProtKB Modified residue 71 71 . . . Note=Phosphothreonine%3B by LRRK2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Modified residue 72 72 . . . Note=Phosphoserine%3B by LRRK2;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Lipidation 202 202 . . . Note=S-geranylgeranyl cysteine;Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Lipidation 203 203 . . . Note=S-geranylgeranyl cysteine;Ontology_term=ECO:0000250;evidence=ECO:0000250 O14966 UniProtKB Alternative sequence 1 72 . . . ID=VSP_045078;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 O14966 UniProtKB Alternative sequence 42 65 . . . ID=VSP_043391;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 O14966 UniProtKB Mutagenesis 71 71 . . . Note=Loss of phosphorylation by LRRK2. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Mutagenesis 71 71 . . . Note=Loss of phosphorylation by LRRK2. Does not stimulate LRRK2 kinase activity%3B when associated with E-72. T->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Mutagenesis 72 72 . . . Note=Loss of phosphorylation by LRRK2. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Mutagenesis 72 72 . . . Note=Loss of phosphorylation by LRRK2. Does not stimulate LRRK2 kinase activity%3B when associated with E-71. S->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Mutagenesis 73 73 . . . Note=Loss of LRRK2 binding. Does not stimulate LRRK2 kinase activity. Localized to the cytosol. M->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Mutagenesis 75 75 . . . Note=Loss of LRRK2 binding. Does not stimulate LRRK2 kinase activity. Localized to the cytosol. R->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29212815;Dbxref=PMID:29212815 O14966 UniProtKB Beta strand 5 15 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 20 27 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Turn 30 32 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 37 40 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 42 52 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 55 63 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 65 70 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 75 78 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 82 89 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 93 109 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 120 125 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 129 131 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 136 145 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Beta strand 149 153 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Turn 156 159 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2 O14966 UniProtKB Helix 162 175 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6HH2