O14943 (O14943_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphofructokinase-P EMBL BAA21891.1

Gene names

Name:

PFK-P EMBL BAA21891.1

Organism

Homo sapiens (Human) EMBL BAA21891.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	412 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU004092 Nucleotide-binding
Molecular function	Kinase RuleBase RU004092 EMBL BAA21891.1 Transferase
Gene Ontology (GO)
Biological process	glycolysis Inferred from direct assay. Source: MGI
Cellular component	6-phosphofructokinase complex Inferred from direct assay. Source: MGI
Molecular function	6-phosphofructokinase activity Inferred from direct assay. Source: MGI ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAA21891.1
	Non-terminal residue	412	1	EMBL BAA21891.1

Sequences

	Sequence		Length	Mass (Da)
	O14943 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: BDE9DC1916C80DF3	FASTA	412	45,604
	10 20 30 40 50 60 ERRFQDAVRL RGRSFAGNLN TYKRLAIKLP DDQIPKTNCN VAVINVGAPA AGMNAGVRSA 70 80 90 100 110 120 VRVGIADGHR MLAIYDGFDG FAKGQIKEIG WTDVGGWTGQ GGSILGTKRV LPGKYLEEIA 130 140 150 160 170 180 TQMRTHSINA LLIIGGFEAY LGLLELSAAR EKHEEFCVPM VMVPATVSNN VPGSDFSIGA 190 200 210 220 230 240 DTALNTITDT CDRIKQSASG TKRRVFIIET MGGYCGYLAN MGGLAAGADA AYIFEEPFDI 250 260 270 280 290 300 RDLQSNVEHL TEKMKTTIQR GLVLRNESCS ENYTTDFIYQ LYSEEGKGVF DCRKNVLGHM 310 320 330 340 350 360 QQGGAPSPFD RNFGTKISAR AMEWITEKLK EARGRGKKFT TDDSICVLGI SKRNVIFQPV 370 380 390 400 410 AELKKQTDFE HRIPKEQWWL KLRPLMKILA KYKASYDVSD SGQLEHVQPW SV

References

[1]	"Cloning of human muscle phosphofructokinase cDNA." Nakajima H., Noguchi T., Yamasaki T., Kono N., Tanaka T., Tarui S. FEBS Lett. 223:113-116(1987) [PubMed: 2822475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Nakajima H. Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D21863 mRNA. Translation: BAA21891.1.
IPI	IPI00639981.
UniGene	Hs.26010.
3D structure databases
HSSP	HSSP built from PDB template 3PFK based on UniProtKB P00512.
ProteinModelPortal	O14943.
ModBase	Search...
Protein-protein interaction databases
STRING	O14943.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	prNOG06932.
HOVERGEN	HBG000976.
Gene expression databases
ArrayExpress	O14943.
Family and domain databases
InterPro	IPR022953. Phosphofructokinase. IPR015912. Phosphofructokinase_CS. IPR000023. Phosphofructokinase_dom. [Graphical view]
Pfam	PF00365. PFK. 1 hit. [Graphical view]
PRINTS	PR00476. PHFRCTKINASE.
SUPFAM	SSF53784. Ppfruckinase. 1 hit.
PROSITE	PS00433. PHOSPHOFRUCTOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O14943_HUMAN

Accession

Primary (citable) accession number: O14943

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	November 16, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.