O14637 (O14637_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Laminin alpha 3b chain EMBL AAC51867.1
Organism	Homo sapiens (Human) EMBL AAC51867.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1486 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Laminin EGF-like domain SAAS SAAS002049 Repeat SAAS SAAS002049
PTM	Disulfide bond SAAS SAAS002049
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC51867.1
	Non-terminal residue	1486	1	EMBL AAC51867.1

Sequences

	Sequence		Length	Mass (Da)
	O14637 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: F2E5EB7EB522E98C	FASTA	1,486	162,497
	10 20 30 40 50 60 ATVGIPGPRA QLHPTYFNLA EAEDLATATC GERGTRRGEP QPELYCKLVG GPTAPGSGHT 70 80 90 100 110 120 IQGQFCDYCN SEDPRKAHPV TNAIDGSERW WQSPPLSSGT QYNRVNLTLD LGQLFHVAYI 130 140 150 160 170 180 LIKFANSPRP ELWVLERSVD FGSTYSPWQY FAHSKVDCLK EFGREANMAV TRDDDVLCVT 190 200 210 220 230 240 EYSRIVPLEN GEVVVSLING RPGAKNFTFS HTLRGVYQGN KHPLAFLRTN TLLGHLISKA 250 260 270 280 290 300 QRDPTVTRRY YYSIKDISIG GQCVCNGHAE VCNINNPEKL FRCECQHHTC GETCDRCCTG 310 320 330 340 350 360 YNQRRLGPAA WEQSHECEAC NCHGHASNCY YDPDVERHEA SLNTQGIYAG GGVCINCQHN 370 380 390 400 410 420 TAGVNCEQCA KGYYRPYGVP VDAPDGCIPC SCDPEHADGC EQGSGRCHCK PNFHGDNCEK 430 440 450 460 470 480 CAIGYNFPFC LRIPIFPVST PSSEDPVAGD IKGCDCNLEG VLPEICDAHG RCLCRPGVEG 490 500 510 520 530 540 PRCDTCRSGF YSFPICQACW CSALGSYQMP CSSVTGQCEC RPGVTGQRCD RCLSGAYDFP 550 560 570 580 590 600 HCQGSSSACD PAGTINWNLG YCQCKLHVEG PTCSRCKLLY WNLDKENPSG CSECKCHKGG 610 620 630 640 650 660 TVSGTGECRQ GDGDCHCKSH VGGDSCDTCE DGYFALEKSN YFGCQGCQCD IGGALSSMCS 670 680 690 700 710 720 GPSGVCQCRE HVVGKVCQRP ENNYYFPDLH HMKYEIEDGS TPNGRDLRFG FDPLAFPEFS 730 740 750 760 770 780 WRGYAQMASV QNDVRITLNV GKSSGSLFRV ILRYVNPGTE AVSGHITIYP SWGAAQSKEI 790 800 810 820 830 840 IFLPSKEPAF VTLPGNGFAD PFSITPGMWV ACIKAEGVLL DYLVLLPRDY YEASDLQLPV 850 860 870 880 890 900 TEPCAYAGPP QENCLLYQHL PVTRFPCTRS CEARHFLLDG EPRPVAVRQP TPAHPVMVDL 910 920 930 940 950 960 SGREVELHLR VRIPQVGPYV VVVEYSTEAA QLFVVDANVK SSGSVLAGQV NIYSCNYSVL 970 980 990 1000 1010 1020 CRSAVIDHMS RIAMYELLTD ADIQLKGHMA RFLLHQVCII PIEEYSAEYV RPQVHCIASY 1030 1040 1050 1060 1070 1080 GRFVNQSATC VSLAHETPPT ALILDVLSGR PFPHLPQQSS PSVDVLPGVT LKAPQNQVTL 1090 1100 1110 1120 1130 1140 RGRVPHLGRY VFVIHFYQAA HPTFPAQVSV DGGWPRAGSF HASFCPHVLG CRDQVIAEQI 1150 1160 1170 1180 1190 1200 EFDISEPEVA ATVKVPEGKS LVLVRVLVVP AENYDSQILH KKSMDKSLEF ITKFCGEKNS 1210 1220 1230 1240 1250 1260 FYLDPQTASR FCKNSARSLV AFYHKGALPC ECHPTGTGPH CSPEGGSAHA SPTSSGGSAP 1270 1280 1290 1300 1310 1320 AVQQATYGFP RCKPKPCSCG RRLCEEMTGQ CRCPPRTVRP QCEVCETHSF SLHPMAGCEG 1330 1340 1350 1360 1370 1380 CNCSRRGTIE AAMPRCDRDS GQCGCKPRIT GRQCDRCASG FYGFPECVPC NCNRDGTEPG 1390 1400 1410 1420 1430 1440 VCDPGTGACL CKENVEGTEC NVCREGSFHL DPANLKGCTS CFCFGVNNQC HSSHKRRTKF 1450 1460 1470 1480 VDMLGWHLET ADRVDIPVSF NPGSNSMVAD LQELPATIHS ASWVAP

References

[1]	"The human alpha3b is a 'full-sized' laminin chain variant with a more widespread tissue expression than the truncated alpha3a." Doliana R., Bellina I., Bucciotti F., Mongiat M., Perris R., Colombatti A. FEBS Lett. 417:65-70(1997) [PubMed: 9395076] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF005258 mRNA. Translation: AAC51867.1.
IPI	IPI01012763.
UniGene	Hs.436367.
3D structure databases
HSSP	HSSP built from PDB template 1KLO based on UniProtKB P02468.
ProteinModelPortal	O14637.
ModBase	Search...
Protein-protein interaction databases
STRING	O14637.
Proteomic databases
PRIDE	O14637.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	prNOG10862.
HOVERGEN	HBG100950.
Gene expression databases
ArrayExpress	O14637.
Family and domain databases
InterPro	IPR013032. EGF-like_reg_CS. IPR002049. EGF_laminin. IPR008211. Laminin_N. [Graphical view]
Pfam	PF00053. Laminin_EGF. 8 hits. PF00055. Laminin_N. 1 hit. [Graphical view]
SMART	SM00180. EGF_Lam. 10 hits. SM00136. LamNT. 1 hit. [Graphical view]
PROSITE	PS00022. EGF_1. 10 hits. PS01248. EGF_LAM_1. 9 hits. PS50027. EGF_LAM_2. 11 hits. PS51117. LAMININ_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O14637_HUMAN

Accession

Primary (citable) accession number: O14637

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	January 25, 2012
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.