O14628 (ZN195_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc finger protein 195

Gene names

Name:	ZNF195
Synonyms:	ZNFP104

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	629 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be involved in transcriptional regulation.
Subcellular location	Nucleus Probable.
Tissue specificity	Expressed in adult heart, brain, placenta, skeletal muscle and pancreas, and in fetal lung, kidney and brain. There is little expression in adult lung, liver and kidney.
Sequence similarities	Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 10 C2H2-type zinc fingers. Contains 1 KRAB domain.
Sequence caution	The sequence BAG57121.1 differs from that shown. Reason: Frameshift at position 118.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
PTM	Acetylation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Non-traceable author statement. Source: UniProtKB transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Non-traceable author statement. Source: UniProtKB
Molecular_function	DNA binding Non-traceable author statement. Source: UniProtKB zinc ion binding Non-traceable author statement Ref.1. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 8 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: O14628-1)

Also known as: A;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: O14628-2)

Also known as: B;

The sequence of this isoform is not available.

Isoform 3 (identifier: O14628-3)

Also known as: C;

The sequence of this isoform is not available.

Isoform 4 (identifier: O14628-4)

The sequence of this isoform differs from the canonical sequence as follows:
     76-147: Missing.

Isoform 5 (identifier: O14628-5)

The sequence of this isoform differs from the canonical sequence as follows:
     125-147: Missing.

Isoform 6 (identifier: O14628-6)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MAGAQ
     125-147: Missing.

Isoform 7 (identifier: O14628-7)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MAGAQ
     76-147: Missing.

Isoform 8 (identifier: O14628-8)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MAGAQ
     76-86: EMGFHHATQAC → GIFFVVTMEII
     87-629: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 629	629	Zinc finger protein 195		PRO_0000047447
Regions
	Domain	4 – 75	72	KRAB
	Zinc finger	244 – 266	23	C2H2-type 1
	Zinc finger	272 – 294	23	C2H2-type 2; degenerate
	Zinc finger	410 – 432	23	C2H2-type 3
	Zinc finger	438 – 460	23	C2H2-type 4
	Zinc finger	466 – 488	23	C2H2-type 5
	Zinc finger	494 – 516	23	C2H2-type 6
	Zinc finger	522 – 544	23	C2H2-type 7
	Zinc finger	550 – 572	23	C2H2-type 8
	Zinc finger	578 – 600	23	C2H2-type 9
	Zinc finger	606 – 628	23	C2H2-type 10
	Region	76 – 243	168	Spacer
Amino acid modifications
	Modified residue	408	1	N6-acetyllysine Ref.7
Natural variations
	Alternative sequence	1	1	M → MAGAQ in isoform 6, isoform 7 and isoform 8.		VSP_036879
	Alternative sequence	76 – 147	72	Missing in isoform 4 and isoform 7.		VSP_036880
	Alternative sequence	76 – 86	11	EMGFHHATQAC → GIFFVVTMEII in isoform 8.		VSP_045071
	Alternative sequence	87 – 629	543	Missing in isoform 8.		VSP_045072
	Alternative sequence	125 – 147	23	Missing in isoform 5 and isoform 6.		VSP_036881
Experimental info
	Sequence conflict	290	1	P → R in BAG53114. Ref.2
	Sequence conflict	352 – 407	56	Missing in BAD18466. Ref.2
	Sequence conflict	558	1	V → A in AAB86596. Ref.1
	Sequence conflict	570	1	K → Q in AAB86596. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (A) [UniParc]. Last modified September 23, 2008. Version 2. Checksum: D048217DFC6BFDFB	FASTA	629	72,332
	10 20 30 40 50 60 MTLLTFRDVA IEFSLEEWKC LDLAQQNLYR DVMLENYRNL FSVGLTVCKP GLITCLEQRK 70 80 90 100 110 120 EPWNVKRQEA ADGHPEMGFH HATQACLELL GSSDLPASAS QSAGITGVNH RAQPGLNVSV 130 140 150 160 170 180 DKFTALCSPG VLQTVKWFLE FRCIFSLAMS SHFTQDLLPE QGIQDAFPKR ILRGYGNCGL 190 200 210 220 230 240 DNLYLRKDWE SLDECKLQKD YNGLNQCSST THSKIFQYNK YVKIFDNFSN LHRRNISNTG 250 260 270 280 290 300 EKPFKCQECG KSFQMLSFLT EHQKIHTGKK FQKCGECGKT FIQCSHFTEP ENIDTGEKPY 310 320 330 340 350 360 KCQECNNVIK TCSVLTKNRI YAGGEHYRCE EFGKVFNQCS HLTEHEHGTE EKPCKYEECS 370 380 390 400 410 420 SVFISCSSLS NQQMILAGEK LSKCETWYKG FNHSPNPSKH QRNEIGGKPF KCEECDSIFK 430 440 450 460 470 480 WFSDLTKHKR IHTGEKPYKC DECGKAYTQS SHLSEHRRIH TGEKPYQCEE CGKVFRTCSS 490 500 510 520 530 540 LSNHKRTHSE EKPYTCEECG NIFKQLSDLT KHKKTHTGEK PYKCDECGKN FTQSSNLIVH 550 560 570 580 590 600 KRIHTGEKPY KCEECGRVFM WFSDITKHKK THTGEKPYKC DECGKNFTQS SNLIVHKRIH 610 620 TGEKPYKCEK CGKAFTQFSH LTVHESIHT
	Isoform 2 (B) (Sequence not available).		–	–
	Isoform 3 (C) (Sequence not available).		–	–
	Isoform 4 [UniParc]. Checksum: 5E06D5041ACBAB0E	FASTA	557	64,658
	10 20 30 40 50 60 MTLLTFRDVA IEFSLEEWKC LDLAQQNLYR DVMLENYRNL FSVGLTVCKP GLITCLEQRK 70 80 90 100 110 120 EPWNVKRQEA ADGHPAMSSH FTQDLLPEQG IQDAFPKRIL RGYGNCGLDN LYLRKDWESL 130 140 150 160 170 180 DECKLQKDYN GLNQCSSTTH SKIFQYNKYV KIFDNFSNLH RRNISNTGEK PFKCQECGKS 190 200 210 220 230 240 FQMLSFLTEH QKIHTGKKFQ KCGECGKTFI QCSHFTEPEN IDTGEKPYKC QECNNVIKTC 250 260 270 280 290 300 SVLTKNRIYA GGEHYRCEEF GKVFNQCSHL TEHEHGTEEK PCKYEECSSV FISCSSLSNQ 310 320 330 340 350 360 QMILAGEKLS KCETWYKGFN HSPNPSKHQR NEIGGKPFKC EECDSIFKWF SDLTKHKRIH 370 380 390 400 410 420 TGEKPYKCDE CGKAYTQSSH LSEHRRIHTG EKPYQCEECG KVFRTCSSLS NHKRTHSEEK 430 440 450 460 470 480 PYTCEECGNI FKQLSDLTKH KKTHTGEKPY KCDECGKNFT QSSNLIVHKR IHTGEKPYKC 490 500 510 520 530 540 EECGRVFMWF SDITKHKKTH TGEKPYKCDE CGKNFTQSSN LIVHKRIHTG EKPYKCEKCG 550 KAFTQFSHLT VHESIHT
	Isoform 5 [UniParc]. Checksum: 2D48AE52C8AE69F8	FASTA	606	69,692
	10 20 30 40 50 60 MTLLTFRDVA IEFSLEEWKC LDLAQQNLYR DVMLENYRNL FSVGLTVCKP GLITCLEQRK 70 80 90 100 110 120 EPWNVKRQEA ADGHPEMGFH HATQACLELL GSSDLPASAS QSAGITGVNH RAQPGLNVSV 130 140 150 160 170 180 DKFTAMSSHF TQDLLPEQGI QDAFPKRILR GYGNCGLDNL YLRKDWESLD ECKLQKDYNG 190 200 210 220 230 240 LNQCSSTTHS KIFQYNKYVK IFDNFSNLHR RNISNTGEKP FKCQECGKSF QMLSFLTEHQ 250 260 270 280 290 300 KIHTGKKFQK CGECGKTFIQ CSHFTEPENI DTGEKPYKCQ ECNNVIKTCS VLTKNRIYAG 310 320 330 340 350 360 GEHYRCEEFG KVFNQCSHLT EHEHGTEEKP CKYEECSSVF ISCSSLSNQQ MILAGEKLSK 370 380 390 400 410 420 CETWYKGFNH SPNPSKHQRN EIGGKPFKCE ECDSIFKWFS DLTKHKRIHT GEKPYKCDEC 430 440 450 460 470 480 GKAYTQSSHL SEHRRIHTGE KPYQCEECGK VFRTCSSLSN HKRTHSEEKP YTCEECGNIF 490 500 510 520 530 540 KQLSDLTKHK KTHTGEKPYK CDECGKNFTQ SSNLIVHKRI HTGEKPYKCE ECGRVFMWFS 550 560 570 580 590 600 DITKHKKTHT GEKPYKCDEC GKNFTQSSNL IVHKRIHTGE KPYKCEKCGK AFTQFSHLTV HESIHT
	Isoform 6 [UniParc]. Checksum: BE8A3DF20C7FF02C	FASTA	610	70,019
	10 20 30 40 50 60 MAGAQTLLTF RDVAIEFSLE EWKCLDLAQQ NLYRDVMLEN YRNLFSVGLT VCKPGLITCL 70 80 90 100 110 120 EQRKEPWNVK RQEAADGHPE MGFHHATQAC LELLGSSDLP ASASQSAGIT GVNHRAQPGL 130 140 150 160 170 180 NVSVDKFTAM SSHFTQDLLP EQGIQDAFPK RILRGYGNCG LDNLYLRKDW ESLDECKLQK 190 200 210 220 230 240 DYNGLNQCSS TTHSKIFQYN KYVKIFDNFS NLHRRNISNT GEKPFKCQEC GKSFQMLSFL 250 260 270 280 290 300 TEHQKIHTGK KFQKCGECGK TFIQCSHFTE PENIDTGEKP YKCQECNNVI KTCSVLTKNR 310 320 330 340 350 360 IYAGGEHYRC EEFGKVFNQC SHLTEHEHGT EEKPCKYEEC SSVFISCSSL SNQQMILAGE 370 380 390 400 410 420 KLSKCETWYK GFNHSPNPSK HQRNEIGGKP FKCEECDSIF KWFSDLTKHK RIHTGEKPYK 430 440 450 460 470 480 CDECGKAYTQ SSHLSEHRRI HTGEKPYQCE ECGKVFRTCS SLSNHKRTHS EEKPYTCEEC 490 500 510 520 530 540 GNIFKQLSDL TKHKKTHTGE KPYKCDECGK NFTQSSNLIV HKRIHTGEKP YKCEECGRVF 550 560 570 580 590 600 MWFSDITKHK KTHTGEKPYK CDECGKNFTQ SSNLIVHKRI HTGEKPYKCE KCGKAFTQFS 610 HLTVHESIHT
	Isoform 7 [UniParc]. Checksum: 2BDEFB89E8A73BA4	FASTA	561	64,986
	10 20 30 40 50 60 MAGAQTLLTF RDVAIEFSLE EWKCLDLAQQ NLYRDVMLEN YRNLFSVGLT VCKPGLITCL 70 80 90 100 110 120 EQRKEPWNVK RQEAADGHPA MSSHFTQDLL PEQGIQDAFP KRILRGYGNC GLDNLYLRKD 130 140 150 160 170 180 WESLDECKLQ KDYNGLNQCS STTHSKIFQY NKYVKIFDNF SNLHRRNISN TGEKPFKCQE 190 200 210 220 230 240 CGKSFQMLSF LTEHQKIHTG KKFQKCGECG KTFIQCSHFT EPENIDTGEK PYKCQECNNV 250 260 270 280 290 300 IKTCSVLTKN RIYAGGEHYR CEEFGKVFNQ CSHLTEHEHG TEEKPCKYEE CSSVFISCSS 310 320 330 340 350 360 LSNQQMILAG EKLSKCETWY KGFNHSPNPS KHQRNEIGGK PFKCEECDSI FKWFSDLTKH 370 380 390 400 410 420 KRIHTGEKPY KCDECGKAYT QSSHLSEHRR IHTGEKPYQC EECGKVFRTC SSLSNHKRTH 430 440 450 460 470 480 SEEKPYTCEE CGNIFKQLSD LTKHKKTHTG EKPYKCDECG KNFTQSSNLI VHKRIHTGEK 490 500 510 520 530 540 PYKCEECGRV FMWFSDITKH KKTHTGEKPY KCDECGKNFT QSSNLIVHKR IHTGEKPYKC 550 560 EKCGKAFTQF SHLTVHESIH T
	Isoform 8 [UniParc]. Checksum: 2190262F0173ED6D	FASTA	90	10,364
	10 20 30 40 50 60 MAGAQTLLTF RDVAIEFSLE EWKCLDLAQQ NLYRDVMLEN YRNLFSVGLT VCKPGLITCL 70 80 90 EQRKEPWNVK RQEAADGHPG IFFVVTMEII

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of a KRAB family zinc finger gene, ZNF195, mapping to chromosome band 11p15.5." Hussey D.J., Parker N.J., Hussey N.D., Little P.F.R., Dobrovic A. Genomics 45:451-455(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), ALTERNATIVE SPLICING.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 4; 6 AND 7). Tissue: Brain, Cerebellum and Subthalamic nucleus.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Stomach.
[4]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4; 5 AND 8). Tissue: Retinoblastoma.
[7]	"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M. Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-408, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF003540 mRNA. Translation: AAB86596.1. AK095720 mRNA. Translation: BAG53114.1. AK131296 mRNA. Translation: BAD18466.1. AK290099 mRNA. Translation: BAF82788.1. AK293679 mRNA. Translation: BAG57121.1. Frameshift. AL833722 mRNA. Translation: CAH56261.1. AC123788 Genomic DNA. No translation available. CH471158 Genomic DNA. Translation: EAX02548.1. CH471158 Genomic DNA. Translation: EAX02549.1. BC121028 mRNA. Translation: AAI21029.1. BM462194 mRNA. No translation available.
IPI	IPI00442264. IPI00470385. IPI00747327. IPI00796632. IPI00925378. IPI00974314.
RefSeq	NP_001123991.1. NM_001130519.2. NP_001123992.1. NM_001130520.2. NP_001229770.1. NM_001242841.1. NP_001229771.1. NM_001242842.1. NP_001229772.1. NM_001242843.1. NP_001243752.1. NM_001256823.1. NP_001243753.1. NM_001256824.1. NP_001243754.1. NM_001256825.1. NP_009083.2. NM_007152.4.
UniGene	Hs.386294.
3D structure databases
ProteinModelPortal	O14628.
ModBase	Search...
Protein-protein interaction databases
IntAct	O14628. 1 interaction.
STRING	9606.ENSP00000005082.
PTM databases
PhosphoSite	O14628.
2D gel databases
REPRODUCTION-2DPAGE	O14628.
Proteomic databases
PaxDb	O14628.
PRIDE	O14628.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000005082; ENSP00000005082; ENSG00000005801. ENST00000343338; ENSP00000344483; ENSG00000005801. ENST00000354599; ENSP00000346613; ENSG00000005801. ENST00000399602; ENSP00000382511; ENSG00000005801. ENST00000429541; ENSP00000387998; ENSG00000005801. ENST00000438262; ENSP00000414353; ENSG00000005801. ENST00000526601; ENSP00000435828; ENSG00000005801. ENST00000528218; ENSP00000436384; ENSG00000005801.
GeneID	7748.
KEGG	hsa:7748.
UCSC	uc001lxs.3. human. uc001lxt.3. human. uc001lxu.3. human. uc001lxv.3. human. uc010qxr.2. human.
Organism-specific databases
CTD	7748.
GeneCards	GC11M003336.
HGNC	HGNC:12986. ZNF195.
HPA	HPA030605.
MIM	602187. gene.
neXtProt	NX_O14628.
PharmGKB	PA37566.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG5048.
HOVERGEN	HBG018163.
InParanoid	O14628.
KO	K09228.
OMA	AYTQSSH.
OrthoDB	EOG4JDH69.
Enzyme and pathway databases
Reactome	REACT_71. Gene Expression.
Gene expression databases
ArrayExpress	O14628.
Bgee	O14628.
CleanEx	HS_ZNF195.
Genevestigator	O14628.
GermOnline	ENSG00000005801. Homo sapiens.
Family and domain databases
Gene3D	3.30.160.60. 11 hits.
InterPro	IPR001909. Krueppel-associated_box. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Pfam	PF01352. KRAB. 1 hit. [Graphical view]
SMART	SM00349. KRAB. 1 hit. SM00355. ZnF_C2H2. 9 hits. [Graphical view]
SUPFAM	SSF109640. Krueppel-associated_box. 1 hit.
PROSITE	PS50805. KRAB. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 9 hits. PS50157. ZINC_FINGER_C2H2_2. 10 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ZNF195. human.
GenomeRNAi	7748.
NextBio	29986.
SOURCE	Search...

Entry information

Entry name

ZN195_HUMAN

Accession

Primary (citable) accession number: O14628
Secondary accession number(s): A8K234 , B3KTK2, B4DEL0, C9JLY9, Q0VAJ6, Q658N8, Q6ZNA9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 121 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.