Reviewed, UniProtKB/Swiss-Prot O14609 (XKRY_HUMAN)

Names and origin

Protein names

Recommended name:
    Testis-specific XK-related protein, Y-linked

Gene names

Name:

XKRY

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Tissue specificity	Testis specific.
Sequence similarities	Belongs to the XK family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	single fertilization Ref.1 Traceable author statement. Source: ProtInc
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 159	159	Testis-specific XK-related protein, Y-linked		PRO_0000190771
Regions
	Transmembrane	1 – 21	21	Potential
	Transmembrane	45 – 65	21	Potential
	Transmembrane	72 – 92	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	O14609-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: B9E81DD842DEF0AB	FASTA	159	18,083
	10 20 30 40 50 60 MFIFNSIADD IFPLISCVGA IHCNILAIRT GNDFAAIKLQ VIKLIYLMIW HSLVIISPVV 70 80 90 100 110 120 TLAFFPASLK QGSLHFLLII YFVLLLTPWL EFSKSGTHLP SNTKIIPAWW VSMDAYLNHA 130 140 150 SICCHQFSCL SAVKLQLSNE ELIRDTRWDI QSYTTDFSF

References

[1]	"Functional coherence of the human Y chromosome." Lahn B.T., Page D.C. Science 278:675-680(1997) [PubMed: 9381176] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF000997 mRNA. Translation: AAC51844.1.
IPI	IPI00023016.
RefSeq	NP_004668.2.
UniGene	Hs.158346
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	O14609.
Genome annotation databases
GeneID	9082.
KEGG	hsa:9082.
Organism-specific databases
CTD	9082.
GeneCards	GC0YM018390.
H-InvDB	HIX0056664. HIX0093760.
HGNC	HGNC:18571. XKRY.
MIM	400015. gene.
PharmGKB	PA38583.
GenAtlas	Search...
Gene expression databases
CleanEx	HS_XKRY.
Genevestigator	O14609.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	34029.
SOURCE	Search...

Entry information

Entry name

XKRY_HUMAN

Accession

Primary (citable) accession number: O14609

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	January 1, 1998
Last modified:	October 13, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.