Reviewed, UniProtKB/Swiss-Prot O14598 (VCY1_HUMAN)

Names and origin

Protein names

Recommended name:
    Testis-specific basic protein Y 1
Alternative name(s):
    Variably charged protein Y
    Basic charge, Y-linked 1

Gene names

Name:	VCY
Synonyms:	BPY1, VCY1A
AND
Name:	VCY1B
Synonyms:	BPY1B

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	125 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
Tissue specificity	Expressed exclusively in testis.
Sequence similarities	Belongs to the VCX/VCY family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 125	125	Testis-specific basic protein Y 1		PRO_0000184663

Sequences

	Sequence		Length	Mass (Da)
	O14598-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: D528561A52592E6C	FASTA	125	12,917
	10 20 30 40 50 60 MSPKPRASGP PAKAKETGKR KSSSQPSPSG PKKKTTKVAE KGEAVRGGRR GKKGAATKMA 70 80 90 100 110 120 AVTAPEAESG PAAPGPSDQP SQELPQHELP PEEPVSEGTQ HDPLSQESEL EEPLSKGRPS TPLSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional coherence of the human Y chromosome." Lahn B.T., Page D.C. Science 278:675-680(1997) [PubMed: 9381176] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C. Nature 423:825-837(2003) [PubMed: 12815422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF000979 mRNA. Translation: AAC51827.1. AC006370 Genomic DNA. Translation: AAF03503.1. BC056508 mRNA. Translation: AAH56508.1.
IPI	IPI00297427.
RefSeq	NP_004670.1. NP_870996.1.
UniGene	Hs.170076 Hs.632284
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENST00000250823; ENSP00000250823; ENSG00000129862; Homo sapiens. [Genome view] ENST00000250825; ENSP00000250825; ENSG00000129864; Homo sapiens. [Genome view]
GeneID	353513. 9084.
KEGG	hsa:353513. hsa:9084.
UCSC	uc004ftc.1. human.
Organism-specific databases
CTD	353513. 9084.
GeneCards	GC0YM014607. GC0YP014607. GC0YP014677.
H-InvDB	HIX0028483. HIX0077341.
HGNC	HGNC:12668. VCY. HGNC:31751. VCY1B.
MIM	400012. gene.
PharmGKB	PA37291.
GenAtlas	Search...
Phylogenomic databases
OMA	EYSPISP
Gene expression databases
CleanEx	HS_VCY.
Genevestigator	O14598.
GermOnline	ENSG00000129862. Homo sapiens. ENSG00000129864. Homo sapiens.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	99822.
SOURCE	Search...

Entry information

Entry name

VCY1_HUMAN

Accession

Primary (citable) accession number: O14598

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	January 1, 1998
Last modified:	November 24, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.