Reviewed,
UniProtKB/Swiss-Prot O14598 (VCY1_HUMAN)
Last modified
November 24, 2009.
Version 61.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Testis-specific basic protein Y 1 Alternative name(s): Variably charged protein Y Basic charge, Y-linked 1 | |||||||||
| Gene names |
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| Organism | Homo sapiens (Human) [Complete proteome] | |||||||||
| Taxonomic identifier | 9606 [NCBI] | |||||||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Protein attributes
| Sequence length | 125 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | May mediate a process in spermatogenesis or may play a role in sex ratio distortion. |
| Tissue specificity | Expressed exclusively in testis. |
| Sequence similarities | Belongs to the VCX/VCY family. |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 125 | 125 | Testis-specific basic protein Y 1 | PRO_0000184663 | |||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Functional coherence of the human Y chromosome." Lahn B.T., Page D.C. Science 278:675-680(1997) [PubMed: 9381176] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. Page D.C.Nature 423:825-837(2003) [PubMed: 12815422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [3] | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| AF000979 mRNA. Translation: AAC51827.1. AC006370 Genomic DNA. Translation: AAF03503.1. BC056508 mRNA. Translation: AAH56508.1. | |
| IPI | IPI00297427. |
| RefSeq | NP_004670.1. NP_870996.1. |
| UniGene | Hs.170076 Hs.632284 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENST00000250823; ENSP00000250823; ENSG00000129862; Homo sapiens. [Genome view] ENST00000250825; ENSP00000250825; ENSG00000129864; Homo sapiens. [Genome view] |
| GeneID | 353513. 9084. |
| KEGG | hsa:353513. hsa:9084. |
| UCSC | uc004ftc.1. human. |
Organism-specific databases | |
| CTD | 353513. 9084. |
| GeneCards | GC0YM014607. GC0YP014607. GC0YP014677. |
| H-InvDB | HIX0028483. HIX0077341. |
| HGNC | HGNC:12668. VCY. HGNC:31751. VCY1B. |
| MIM | 400012. gene. |
| PharmGKB | PA37291. |
| GenAtlas | Search... |
Phylogenomic databases | |
| OMA | EYSPISP |
Gene expression databases | |
| CleanEx | HS_VCY. |
| Genevestigator | O14598. |
| GermOnline | ENSG00000129862. Homo sapiens. ENSG00000129864. Homo sapiens. |
Family and domain databases | |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 99822. |
| SOURCE | Search... |
Entry information
| Entry name | VCY1_HUMAN | ||||||||
| Accession | Primary (citable) accession number: O14598 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. | ||||||||
Relevant documents
| Human chromosome Y Human chromosome Y: entries, gene names and cross-references to MIM |
| MIM cross-references Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot |
| SIMILARITY comments Index of protein domains and families |

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