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Protein

Serine/threonine-protein phosphatase

Gene

ppt-1

Organism
Neurospora crassa
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:ppt-1Imported
Synonyms:B20D17.050Imported
ORF Names:GE21DRAFT_8072Imported
OrganismiNeurospora crassaImported
Taxonomic identifieri5141 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000053122 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5141.EFNCRP00000007547.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 109102TPR_REGIONInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0376. Eukaryota.
COG0639. LUCA.
HOGENOMiHOG000172698.
PhylomeDBiO14428.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11668:SF21. PTHR11668:SF21. 2 hits.
PfamiPF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
SM00028. TPR. 3 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
SSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O14428-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTPQEQAIA FKNEGNKAFA AHDWPKAIEF YDKAIELNDK EPTFWSNRAQ
60 70 80 90 100
AHLKTEAYGY AIRDATKAIE LNPGFVKAYY RRATAYAAIL NPKEAVKDFK
110 120 130 140 150
TCVKIAPDNK DAKLKLVECE KIVRQLAFFA AIEVGDELSA AEGLDVESMA
160 170 180 190 200
VDASYDGVRL EGNEMTQEFI DDMIERFKRG KLIHKKYVYQ IIIAVRNIVY
210 220 230 240 250
NEPTMVEVDI PEDVQLTVCG DTHGQYFDLM ELFRLNGFPS DKHYYLFNGD
260 270 280 290 300
FVDRGSWSTE IALLLYAYKW LRPNGFFINR GNHETDDMNR VYGFEGECKH
310 320 330 340 350
KYNERTYKLF SESFSALPLA TLIGKKFLVL HGGLFSDDNV TLDDIRKLDR
360 370 380 390 400
HKQKQPGQAG LMMEMLWTDP QPFPGRGPSK RGVGMQFGPD VTKRFCDKNG
410 420 430 440 450
LEAIIRSHEV RMDGYEEEHD GKCITVFSAP KYCDMTENKG AYINIGPDYK
460 470
LKFSQFDAVP HPNIKPMAYA QSSVMSSLM
Length:479
Mass (Da):54,666
Last modified:January 1, 1998 - v1
Checksum:iA1D9712E146F87CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89985 mRNA. Translation: AAB65138.1.
BX294023 Genomic DNA. Translation: CAD70968.1.
KN389769 Genomic DNA. Translation: KHE79986.1.
PIRiT46576.

Genome annotation databases

EnsemblFungiiKHE79986; KHE79986; GE21DRAFT_8072.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89985 mRNA. Translation: AAB65138.1.
BX294023 Genomic DNA. Translation: CAD70968.1.
KN389769 Genomic DNA. Translation: KHE79986.1.
PIRiT46576.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5141.EFNCRP00000007547.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiKHE79986; KHE79986; GE21DRAFT_8072.

Phylogenomic databases

eggNOGiKOG0376. Eukaryota.
COG0639. LUCA.
HOGENOMiHOG000172698.
PhylomeDBiO14428.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11668:SF21. PTHR11668:SF21. 2 hits.
PfamiPF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
SM00028. TPR. 3 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
SSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "ppt-1, a Neurospora crassa PPT/PP5 subfamily serine/threonine protein phosphatase."
    Yatzkan E., Yarden O.
    Biochim. Biophys. Acta 1353:18-22(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Schulte U., Aign V., Hoheisel J., Brandt P., Fartmann B., Holland R., Nyakatura G., Mewes H.W., Mannhaupt G.
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. German Neurospora genome project
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. "Draft genome sequence of Neurospora crassa strain FGSC 73."
    DOE Joint Genome Institute
    Baker S.E., Grigoriev I., Haridas S., LaButti K., McCluskey K.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 73Imported.

Entry informationi

Entry nameiO14428_NEUCS
AccessioniPrimary (citable) accession number: O14428
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.