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O14400

- GPDM_SCHPO

UniProt

O14400 - GPDM_SCHPO

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Protein
Glycerol-3-phosphate dehydrogenase, mitochondrial
Gene
gut2, SPCC1223.03c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

FAD By similarity.

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi69 – 9729FAD Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase activity Source: PomBase
  2. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. NADH oxidation Source: PomBase
  2. carbohydrate metabolic process Source: PomBase
  3. glycerol catabolic process Source: UniProtKB-UniPathway
  4. glycerol-3-phosphate metabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

ReactomeiREACT_207636. Fatty acid, triacylglycerol, and ketone body metabolism.
UniPathwayiUPA00618; UER00673.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase, mitochondrial (EC:1.1.5.3)
Short name:
GPD-M
Short name:
GPDH-M
Gene namesi
Name:gut2
ORF Names:SPCC1223.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome III

Organism-specific databases

PomBaseiSPCC1223.03c.

Subcellular locationi

Mitochondrion By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: PomBase
  2. mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 649Glycerol-3-phosphate dehydrogenase, mitochondrialPRO_0000010433
Transit peptidei1 – ?Mitochondrion Reviewed prediction

Proteomic databases

MaxQBiO14400.

Interactioni

Protein-protein interaction databases

BioGridi275787. 11 interactions.
MINTiMINT-4672763.
STRINGi4896.SPCC1223.03c-1.

Structurei

3D structure databases

ProteinModelPortaliO14400.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004813.
KOiK00111.
OMAiKHLTESY.
OrthoDBiEOG7NSBB6.
PhylomeDBiO14400.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O14400-1 [UniParc]FASTAAdd to Basket

« Hide

MFSIFKRRSV QAALAASGLV GGAVFYSDFI KRPAPSHFNP QFTPFTKSLA    50
PPPSRETLLK NVEDISKFDV LIIGGGATGT GVAVDASTRG LNVCLLEKTD 100
FASETSSKST KMAHGGVRYL EKAVFQLSKA QLDLVIEALN ERANMLRTAP 150
HLCTVLPIMI PVYKWWQVPY FFVGCKIYDW VAGSKNLRAS TIFSKETTVA 200
IAPMLDDSNL KASCVYHDGS FNDTRMNTTL AVTAIDNGAT VLNYMEVKKL 250
LKSKDNKLEG VLAIDRETGK EYQIKATSVV NATGPFSDKI LEMDADPQGE 300
PPKTAQFPRM VVPSAGVHVV LPEYYCPPNI GILDPSTSDN RVMFFLPWQG 350
KVIAGTTDKP LSSVPTNPTP SEDDIQLILK ELQKYLVFPV DREDVLSAWC 400
GIRPLVRDPS TVPPGTDPTT GETQGLVRSH FIFKSDTGLL TISGGKWTTY 450
REMAEETVNE LIKDHDFGKA LKPCQTKKLI LVGGENYYKN YSARLIHEYH 500
IPLRLAKHLS HNYGSRAPLI LELYSKTDFN KLPVTLADKE VFAPSSDASS 550
DKSVSYASFD EPFTVAELKY SIKYEYTRTP TDFLARRTRL AFLDARQALQ 600
AVAGVTHVMK EEFGWDDATT DKLAQEARDY IGGMGVSSDR FDVKQFEVK 649
Length:649
Mass (Da):71,873
Last modified:January 1, 1998 - v1
Checksum:i65702D1FDE831E6A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y14993 Genomic DNA. Translation: CAA75227.1.
CU329672 Genomic DNA. Translation: CAA20872.1.
PIRiT40863.
RefSeqiNP_588348.1. NM_001023339.2.

Genome annotation databases

EnsemblFungiiSPCC1223.03c.1; SPCC1223.03c.1:pep; SPCC1223.03c.
GeneIDi2539217.
KEGGispo:SPCC1223.03c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y14993 Genomic DNA. Translation: CAA75227.1 .
CU329672 Genomic DNA. Translation: CAA20872.1 .
PIRi T40863.
RefSeqi NP_588348.1. NM_001023339.2.

3D structure databases

ProteinModelPortali O14400.
ModBasei Search...

Protein-protein interaction databases

BioGridi 275787. 11 interactions.
MINTi MINT-4672763.
STRINGi 4896.SPCC1223.03c-1.

Proteomic databases

MaxQBi O14400.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPCC1223.03c.1 ; SPCC1223.03c.1:pep ; SPCC1223.03c .
GeneIDi 2539217.
KEGGi spo:SPCC1223.03c.

Organism-specific databases

PomBasei SPCC1223.03c.

Phylogenomic databases

eggNOGi COG0578.
HOGENOMi HOG000004813.
KOi K00111.
OMAi KHLTESY.
OrthoDBi EOG7NSBB6.
PhylomeDBi O14400.

Enzyme and pathway databases

UniPathwayi UPA00618 ; UER00673 .
Reactomei REACT_207636. Fatty acid, triacylglycerol, and ketone body metabolism.

Miscellaneous databases

NextBioi 20800387.
PROi O14400.

Family and domain databases

InterProi IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view ]
Pfami PF01266. DAO. 1 hit.
[Graphical view ]
PRINTSi PR01001. FADG3PDH.
PROSITEi PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Hansen K.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiGPDM_SCHPO
AccessioniPrimary (citable) accession number: O14400
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: September 3, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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