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Protein

Polyadenylate-binding protein 2

Gene

pab2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • poly(A) binding Source: PomBase

GO - Biological processi

  • nuclear-transcribed mRNA poly(A) tail shortening Source: PomBase
  • positive regulation of polynucleotide adenylyltransferase activity Source: InterPro

Keywordsi

Molecular functionRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyadenylate-binding protein 2
Short name:
PABP-2
Short name:
Poly(A)-binding protein 2
Alternative name(s):
Poly(A)-binding protein II
Short name:
PABII
Gene namesi
Name:pab2
ORF Names:SPBC16E9.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC16E9.12c.
PomBaseiSPBC16E9.12c. pab2.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • nuclear chromatin Source: PomBase
  • nucleolus Source: PomBase
  • nucleoplasm Source: PomBase
  • nucleus Source: PomBase
  • polysome Source: PomBase

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000817211 – 166Polyadenylate-binding protein 2Add BLAST166

Proteomic databases

MaxQBiO14327.
PRIDEiO14327.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi276285. 309 interactors.
IntActiO14327. 4 interactors.
MINTiMINT-4672329.
STRINGi4896.SPBC16E9.12c.1.

Structurei

3D structure databases

ProteinModelPortaliO14327.
SMRiO14327.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 132RRMPROSITE-ProRule annotationAdd BLAST78

Phylogenomic databases

HOGENOMiHOG000208465.
InParanoidiO14327.
KOiK14396.
OMAiEGSMQID.
OrthoDBiEOG092C3SCB.
PhylomeDBiO14327.

Family and domain databases

InterProiView protein in InterPro
IPR034911. PABP2.
IPR000504. RRM_dom.
PANTHERiPTHR24012:SF667. PTHR24012:SF667. 1 hit.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.

Sequencei

Sequence statusi: Complete.

O14327-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQDALDTQ EKELLEMKER VAEMEAEAAK LRAMQEQLDN ETEALRNDKE
60 70 80 90 100
SIDAQSVYVG NVDYSVTPEE LQSHFASCGS VNRVTILCDK FTGHPKGFAY
110 120 130 140 150
IEFSEPSLVP NALLLNGSML HERPLKVTPK RTNVPGMSRG RGRGRGRGRG
160
RGRGGYRGRA RGFAPY
Length:166
Mass (Da):18,461
Last modified:January 1, 1998 - v1
Checksum:iA602B5EFC55600E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB16904.1.
PIRiT39586.
RefSeqiNP_595794.1. NM_001021695.2.

Genome annotation databases

EnsemblFungiiSPBC16E9.12c.1; SPBC16E9.12c.1:pep; SPBC16E9.12c.
GeneIDi2539733.
KEGGispo:SPBC16E9.12c.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPAB2_SCHPO
AccessioniPrimary (citable) accession number: O14327
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: January 1, 1998
Last modified: July 5, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names