Skip Header

Contribute Send feedback
Read comments (?) or add your own

O14313 (PMP20_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative peroxiredoxin pmp20
EC=1.11.1.15
Alternative name(s):
Peroxisomal membrane protein pmp20
Thioredoxin reductase
Gene names
Name:pmp20
ORF Names:SPCC330.06c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length156 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.

Subcellular location

Peroxisome Potential.

Sequence similarities

Belongs to the peroxiredoxin 2 family.

Contains 1 thioredoxin domain.

Ontologies

Keywords
   Cellular componentPeroxisome
   DomainRedox-active center
   Molecular functionOxidoreductase
Peroxidase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processcell redox homeostasis

Inferred from sequence or structural similarity. Source: GeneDB_Spombe

hydrogen peroxide catabolic process

Inferred by curator. Source: GeneDB_Spombe

removal of superoxide radicals

Inferred by curator. Source: GeneDB_Spombe

   Cellular componentcytosol

Inferred from direct assay. Source: GeneDB_Spombe

nucleus

Inferred from direct assay. Source: GeneDB_Spombe

peroxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionthioredoxin peroxidase activity

Inferred from sequence or structural similarity. Source: GeneDB_Spombe

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 156156Putative peroxiredoxin pmp20
PRO_0000056609

Regions

Domain2 – 156155Thioredoxin
Motif154 – 1563Microbody targeting signal By similarity

Experimental info

Sequence conflict201E → K in CAA05528. Ref.1

Sequences

Sequence LengthMass (Da)Tools
O14313 [UniParc].

Last modified April 27, 2001. Version 2.
Checksum: 234DC024251F41D2

FASTA15616,675
        10         20         30         40         50         60 
MVAVGSTLPK VTLWENKPEE VVEFPSQGKF IIVGVPGAFT PPCSSQVPGY IANEKQFAAK 

        70         80         90        100        110        120 
GISGIYVVAV NDVFVTKAWK KSFDGGEQSG VHFVADWNGE FTKAFDAGFD ASGLLGPLRS 

       130        140        150 
KRYAAVVENG KVVKVFIENE VTDVDISSAD KVLSSL

« Hide

References

« Hide 'large scale' references
[1]Lenaers G., Perret E., Delpech B., Picard A., Caput D.
Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: 972 / ATCC 24843.
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ002536 mRNA. Translation: CAA05528.1.
CU329672 Genomic DNA. Translation: CAA20911.1.
PIRT41316.
RefSeqNP_587706.1. NM_001022701.1.

3D structure databases

ProteinModelPortalO14313.
ModBaseSearch...

Protein-protein interaction databases

STRINGO14313.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPCC330.06c.1; SPCC330.06c.1:pep; SPCC330.06c.
GeneID2538981.
GenomeReviewsGene locus pmp20 in contig CU329672_GR.
KEGGspo:SPCC330.06c.
NMPDRfig|4896.1.peg.44.

Organism-specific databases

GeneDB_SpombeSPCC330.06c.

Phylogenomic databases

eggNOGfuNOG10623.
GeneTreeEFGT00050000004003.
HOGENOMHBG493509.
OMADTIACIS.
OrthoDBEOG4RR9SW.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-002075-MONOMER.

Gene expression databases

ArrayExpressO14313.

Family and domain databases

InterProIPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
Gene3DG3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KOK03386.
PfamPF08534. Redoxin. 1 hit.
[Graphical view]
SUPFAMSSF52833. Thiordxn-like_fd. 1 hit.
PROSITEPS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePMP20_SCHPO
AccessionPrimary (citable) accession number: O14313
Secondary accession number(s): O74877
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: April 27, 2001
Last modified: December 14, 2011
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents