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Protein

Putative aldehyde dehydrogenase-like protein C9E9.09c

Gene

SPAC9E9.09c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei171Transition state stabilizerBy similarity1
Active sitei270Proton acceptorPROSITE-ProRule annotation1
Active sitei304NucleophilePROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi247 – 252NADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

ReactomeiR-SPO-196757. Metabolism of folate and pterines.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase-like protein C9E9.09c (EC:1.2.1.-)
Gene namesi
ORF Names:SPAC9E9.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC9E9.09c.
PomBaseiSPAC9E9.09c.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • Golgi apparatus Source: PomBase
  • mitochondrial matrix Source: PomBase
  • nucleus Source: PomBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000565951 – 503Putative aldehyde dehydrogenase-like protein C9E9.09cAdd BLAST503

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei248Phosphoserine1 Publication1
Modified residuei501Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO14293.
PRIDEiO14293.

PTM databases

iPTMnetiO14293.

Interactioni

Protein-protein interaction databases

BioGridi279414. 63 interactors.
MINTiMINT-4672040.
STRINGi4896.SPAC9E9.09c.1.

Structurei

3D structure databases

ProteinModelPortaliO14293.
SMRiO14293.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

HOGENOMiHOG000271505.
InParanoidiO14293.
KOiK00128.
OMAiWINLSQA.
OrthoDBiEOG092C1LLH.
PhylomeDBiO14293.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiView protein in InterPro
IPR016161. Ald_DH/histidinol_DH.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
PfamiView protein in Pfam
PF00171. Aldedh. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiView protein in PROSITE
PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.

Sequencei

Sequence statusi: Complete.

O14293-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKLVDHVE ITVPTGKTYI QPVGLFINNQ HVDSVHGGRV KVYSPSTEKL
60 70 80 90 100
ICEVADADEE DVDIAVKVAR AAFQTDAPWR KFSSAQRGRC LSRLADCIEQ
110 120 130 140 150
NLEYLASIET LDNGKSITLA RGDVQAAADC FRYYGGWADK DYGQTIETDI
160 170 180 190 200
KRFAYTRHEP IGVCGQIIPW NFPFLMCAWK IAPAVACGNT IILKTAELTP
210 220 230 240 250
LSALCLTKFV PECGFPPGVI NVLSGDGRRC GNAISSHMDI DKVAFTGSTG
260 270 280 290 300
VGRMVMRAAA SSNLKKVTLE LGGKSPNIVF NDADLDSAAV WTNYGIFYNS
310 320 330 340 350
GQVCCAGSRV YVQEDVYDEF IKRMVAKAKT LKVGDPFAED TFQGAQVSKQ
360 370 380 390 400
QYERIVSYIE SGIAHGAKLE IGGKRHGNLG YFVEPTILSN VTEDMAVGKE
410 420 430 440 450
EIFGPVLAVI KFKTIEEAIR RGNNSTYGLA AGVHTNNITN AIKVSNALEA
460 470 480 490 500
GTVWVNCYNL LHHQIPFGGY KESGIGRELG SYGLTNYTQT KAVHINLGMD

SPI
Length:503
Mass (Da):54,768
Last modified:January 1, 1998 - v1
Checksum:iA7787A2181FB9CD5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti378N → Y in BAA13907 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16407.1.
D89246 mRNA. Translation: BAA13907.1.
PIRiT39216.
T43153.
RefSeqiNP_594582.1. NM_001020011.2.

Genome annotation databases

EnsemblFungiiSPAC9E9.09c.1; SPAC9E9.09c.1:pep; SPAC9E9.09c.
GeneIDi2542976.
KEGGispo:SPAC9E9.09c.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiYF19_SCHPO
AccessioniPrimary (citable) accession number: O14293
Secondary accession number(s): P78895
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2003
Last sequence update: January 1, 1998
Last modified: July 5, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families