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O14293 (YF19_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative aldehyde dehydrogenase-like protein C9E9.09c

EC=1.2.1.-
Gene names
ORF Names:SPAC9E9.09c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 503503Putative aldehyde dehydrogenase-like protein C9E9.09c
PRO_0000056595

Regions

Nucleotide binding247 – 2526NAD By similarity

Sites

Active site2701Proton acceptor By similarity
Active site3041Nucleophile By similarity
Site1711Transition state stabilizer By similarity

Amino acid modifications

Modified residue2481Phosphoserine Ref.3
Modified residue5011Phosphoserine Ref.3

Experimental info

Sequence conflict3781N → Y in BAA13907. Ref.2

Sequences

Sequence LengthMass (Da)Tools
O14293 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: A7787A2181FB9CD5

FASTA50354,768
        10         20         30         40         50         60 
MSTKLVDHVE ITVPTGKTYI QPVGLFINNQ HVDSVHGGRV KVYSPSTEKL ICEVADADEE 

        70         80         90        100        110        120 
DVDIAVKVAR AAFQTDAPWR KFSSAQRGRC LSRLADCIEQ NLEYLASIET LDNGKSITLA 

       130        140        150        160        170        180 
RGDVQAAADC FRYYGGWADK DYGQTIETDI KRFAYTRHEP IGVCGQIIPW NFPFLMCAWK 

       190        200        210        220        230        240 
IAPAVACGNT IILKTAELTP LSALCLTKFV PECGFPPGVI NVLSGDGRRC GNAISSHMDI 

       250        260        270        280        290        300 
DKVAFTGSTG VGRMVMRAAA SSNLKKVTLE LGGKSPNIVF NDADLDSAAV WTNYGIFYNS 

       310        320        330        340        350        360 
GQVCCAGSRV YVQEDVYDEF IKRMVAKAKT LKVGDPFAED TFQGAQVSKQ QYERIVSYIE 

       370        380        390        400        410        420 
SGIAHGAKLE IGGKRHGNLG YFVEPTILSN VTEDMAVGKE EIFGPVLAVI KFKTIEEAIR 

       430        440        450        460        470        480 
RGNNSTYGLA AGVHTNNITN AIKVSNALEA GTVWVNCYNL LHHQIPFGGY KESGIGRELG 

       490        500 
SYGLTNYTQT KAVHINLGMD SPI 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 254-503.
Strain: PR745.
[3]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-248 AND SER-501, IDENTIFICATION BY MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB16407.1.
D89246 mRNA. Translation: BAA13907.1.
PIRT39216.
T43153.
RefSeqNP_594582.1. NM_001020011.2.

3D structure databases

ProteinModelPortalO14293.
SMRO14293. Positions 23-499.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid279414. 66 interactions.
MINTMINT-4672040.
STRING4896.SPAC9E9.09c-1.

Proteomic databases

PaxDbO14293.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC9E9.09c.1; SPAC9E9.09c.1:pep; SPAC9E9.09c.
GeneID2542976.
KEGGspo:SPAC9E9.09c.

Organism-specific databases

PomBaseSPAC9E9.09c.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00128.
OMAQTIPVQG.
OrthoDBEOG7S226Z.
PhylomeDBO14293.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20804009.

Entry information

Entry nameYF19_SCHPO
AccessionPrimary (citable) accession number: O14293
Secondary accession number(s): P78895
Entry history
Integrated into UniProtKB/Swiss-Prot: May 16, 2003
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names