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O14293

- YF19_SCHPO

UniProt

O14293 - YF19_SCHPO

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Protein

Putative aldehyde dehydrogenase-like protein C9E9.09c

Gene
SPAC9E9.09c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei171 – 1711Transition state stabilizer By similarity
Active sitei270 – 2701Proton acceptor By similarity
Active sitei304 – 3041Nucleophile By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi247 – 2526NAD By similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: PomBase
  2. aldehyde dehydrogenase [NAD(P)+] activity Source: PomBase

GO - Biological processi

  1. acetate biosynthetic process Source: PomBase
  2. ethanol catabolic process Source: PomBase
  3. NADPH regeneration Source: PomBase
  4. pyruvate metabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase-like protein C9E9.09c (EC:1.2.1.-)
Gene namesi
ORF Names:SPAC9E9.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC9E9.09c.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: PomBase
  2. cytosol Source: PomBase
  3. Golgi apparatus Source: PomBase
  4. mitochondrial matrix Source: PomBase
  5. nucleus Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 503503Putative aldehyde dehydrogenase-like protein C9E9.09cPRO_0000056595Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei248 – 2481Phosphoserine1 Publication
Modified residuei501 – 5011Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO14293.
PaxDbiO14293.

Interactioni

Protein-protein interaction databases

BioGridi279414. 67 interactions.
MINTiMINT-4672040.
STRINGi4896.SPAC9E9.09c-1.

Structurei

3D structure databases

ProteinModelPortaliO14293.
SMRiO14293. Positions 23-499.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiSKMTAME.
OrthoDBiEOG7S226Z.
PhylomeDBiO14293.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR015657. Aminobutyraldehyde_DH.
[Graphical view]
PANTHERiPTHR11699:SF46. PTHR11699:SF46. 1 hit.
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O14293-1 [UniParc]FASTAAdd to Basket

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MSTKLVDHVE ITVPTGKTYI QPVGLFINNQ HVDSVHGGRV KVYSPSTEKL    50
ICEVADADEE DVDIAVKVAR AAFQTDAPWR KFSSAQRGRC LSRLADCIEQ 100
NLEYLASIET LDNGKSITLA RGDVQAAADC FRYYGGWADK DYGQTIETDI 150
KRFAYTRHEP IGVCGQIIPW NFPFLMCAWK IAPAVACGNT IILKTAELTP 200
LSALCLTKFV PECGFPPGVI NVLSGDGRRC GNAISSHMDI DKVAFTGSTG 250
VGRMVMRAAA SSNLKKVTLE LGGKSPNIVF NDADLDSAAV WTNYGIFYNS 300
GQVCCAGSRV YVQEDVYDEF IKRMVAKAKT LKVGDPFAED TFQGAQVSKQ 350
QYERIVSYIE SGIAHGAKLE IGGKRHGNLG YFVEPTILSN VTEDMAVGKE 400
EIFGPVLAVI KFKTIEEAIR RGNNSTYGLA AGVHTNNITN AIKVSNALEA 450
GTVWVNCYNL LHHQIPFGGY KESGIGRELG SYGLTNYTQT KAVHINLGMD 500
SPI 503
Length:503
Mass (Da):54,768
Last modified:January 1, 1998 - v1
Checksum:iA7787A2181FB9CD5
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti378 – 3781N → Y in BAA13907. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16407.1.
D89246 mRNA. Translation: BAA13907.1.
PIRiT39216.
T43153.
RefSeqiNP_594582.1. NM_001020011.2.

Genome annotation databases

EnsemblFungiiSPAC9E9.09c.1; SPAC9E9.09c.1:pep; SPAC9E9.09c.
GeneIDi2542976.
KEGGispo:SPAC9E9.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16407.1 .
D89246 mRNA. Translation: BAA13907.1 .
PIRi T39216.
T43153.
RefSeqi NP_594582.1. NM_001020011.2.

3D structure databases

ProteinModelPortali O14293.
SMRi O14293. Positions 23-499.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 279414. 67 interactions.
MINTi MINT-4672040.
STRINGi 4896.SPAC9E9.09c-1.

Proteomic databases

MaxQBi O14293.
PaxDbi O14293.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC9E9.09c.1 ; SPAC9E9.09c.1:pep ; SPAC9E9.09c .
GeneIDi 2542976.
KEGGi spo:SPAC9E9.09c.

Organism-specific databases

PomBasei SPAC9E9.09c.

Phylogenomic databases

eggNOGi COG1012.
HOGENOMi HOG000271505.
KOi K00128.
OMAi SKMTAME.
OrthoDBi EOG7S226Z.
PhylomeDBi O14293.

Miscellaneous databases

NextBioi 20804009.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR015657. Aminobutyraldehyde_DH.
[Graphical view ]
PANTHERi PTHR11699:SF46. PTHR11699:SF46. 1 hit.
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
    Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
    DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 254-503.
    Strain: PR745.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-248 AND SER-501, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiYF19_SCHPO
AccessioniPrimary (citable) accession number: O14293
Secondary accession number(s): P78895
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2003
Last sequence update: January 1, 1998
Last modified: June 11, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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