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Protein

Transcription factor prr1

Gene

prr1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in oxidative stress. Transcription factor that acts upon trr1 and ctt1.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi7 – 111By similarityAdd BLAST105

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processSensory transduction, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-SPO-3371453. Regulation of HSF1-mediated heat shock response.
R-SPO-3371511. HSF1 activation.
R-SPO-3371568. Attenuation phase.
R-SPO-3371571. HSF1-dependent transactivation.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor prr1
Alternative name(s):
Pombe response regulator 1
Gene namesi
Name:prr1
ORF Names:SPAC8C9.14
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC8C9.14.
PomBaseiSPAC8C9.14. prr1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245941 – 539Transcription factor prr1Add BLAST539

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei221Phosphothreonine1 Publication1
Modified residuei223Phosphoserine1 Publication1
Modified residuei4184-aspartylphosphatePROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO14283.
PRIDEiO14283.

PTM databases

iPTMnetiO14283.

Interactioni

Protein-protein interaction databases

BioGridi278250. 11 interactors.
MINTiMINT-4671965.
STRINGi4896.SPAC8C9.14.1.

Structurei

3D structure databases

ProteinModelPortaliO14283.
SMRiO14283.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini369 – 483Response regulatoryPROSITE-ProRule annotationAdd BLAST115

Sequence similaritiesi

In the N-terminal section; belongs to the HSF family.Curated

Phylogenomic databases

InParanoidiO14283.
KOiK15859.
OMAiNWQSPGQ.
OrthoDBiEOG092C2G9O.
PhylomeDBiO14283.

Family and domain databases

CDDicd00156. REC. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR000232. HSF_DNA-bd.
IPR027725. HSF_fam.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR014402. Sig_transdc_resp-reg_Skn7.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PANTHERiPTHR10015. PTHR10015. 1 hit.
PfamiView protein in Pfam
PF00447. HSF_DNA-bind. 1 hit.
PF00072. Response_reg. 1 hit.
PIRSFiPIRSF002595. RR_SKN7. 1 hit.
PRINTSiPR00056. HSFDOMAIN.
SMARTiView protein in SMART
SM00415. HSF. 1 hit.
SM00448. REC. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS00434. HSF_DOMAIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

O14283-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSSNGSSDF VRKLFNMLEE PEYRHILRWS DSGDSFIVLD TNEFTKTILP
60 70 80 90 100
RHFKHSNFAS FVRQLNKYDF HKVRHEEGAP SIYGEGAWEF RHDDFQLHHK
110 120 130 140 150
DLLDNIKRKA PSKRNLANEN TAPVIENLKQ QVDSILDFQK LLDRNLSGLA
160 170 180 190 200
TSYQTILLKM FELKRGIESR DLLMSSIISY LCDLEGSTQR QANPGAMFVP
210 220 230 240 250
SHPLQELLNA YQALAKGQVA TTSPQQIPNQ IQQASAATTA SSKMTVDTNL
260 270 280 290 300
GTAQPSLYNT PSSDYELANQ EKPADSMASA ASLNTPLSSN DHSLNPHAHG
310 320 330 340 350
SYPMYEKFQP IQHPNPGSFT THLDSNASMA KSFSQISNDS LAKASSVATS
360 370 380 390 400
MSQMGAAVPT TGLWKRQPRI LLVEDDELSR RMTIKFLTSF DCQVDVAVDG
410 420 430 440 450
IGAVNKANAG GFDLILMDFI LPNLDGLSVT CLIRQYDHNT PILAITSNIS
460 470 480 490 500
MNDAVTYFNH GVTDLLVKPF TKLTLLQLLK KQLLNLLQAD NSINMSDVPS
510 520 530
TKEAKDDKAP VTFYLENDAP MYPQQMLQDP IQADLQHPH
Length:539
Mass (Da):60,046
Last modified:January 1, 1999 - v2
Checksum:iF3B4945C595B2871
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041768 mRNA. Translation: BAB16722.1.
CU329670 Genomic DNA. Translation: CAB16301.1.
AB027943 Genomic DNA. Translation: BAA87247.1.
PIRiT39150.
RefSeqiNP_594284.1. NM_001019707.2.

Genome annotation databases

EnsemblFungiiSPAC8C9.14.1; SPAC8C9.14.1:pep; SPAC8C9.14.
GeneIDi2541756.
KEGGispo:SPAC8C9.14.

Similar proteinsi

Entry informationi

Entry nameiPRR1_SCHPO
AccessioniPrimary (citable) accession number: O14283
Secondary accession number(s): Q9UTX5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: January 1, 1999
Last modified: October 25, 2017
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families