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O14259

- SFP47_SCHPO

UniProt

O14259 - SFP47_SCHPO

Protein

Ubp4-interactor sfp47

Gene

sfp47

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 2 (01 May 1999)
      Previous versions | rss
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    Functioni

    Required for the regulation of activity and recruitment of ubp4 to endosomes.1 Publication

    GO - Molecular functioni

    1. protein binding Source: PomBase

    GO - Biological processi

    1. cellular protein localization Source: PomBase
    2. negative regulation of ubiquitin-specific protease activity Source: PomBase

    Keywords - Biological processi

    Ubl conjugation pathway

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubp4-interactor sfp47
    Gene namesi
    Name:sfp47
    ORF Names:SPAC7D4.02c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC7D4.02c.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: PomBase
    2. cytosol Source: PomBase
    3. endosome Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Endosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 415415Ubp4-interactor sfp47PRO_0000303943Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei221 – 2211Phosphoserine1 Publication
    Modified residuei226 – 2261Phosphoserine1 Publication
    Modified residuei231 – 2311Phosphothreonine1 Publication
    Modified residuei235 – 2351Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiO14259.

    Interactioni

    Subunit structurei

    Interacts with ubp4.1 Publication

    Protein-protein interaction databases

    BioGridi278568. 6 interactions.
    MINTiMINT-4671825.
    STRINGi4896.SPAC7D4.02c-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO14259.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini352 – 41564SH3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 SH3 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    SH3 domain

    Phylogenomic databases

    eggNOGiNOG303711.
    OMAiANPISAY.
    OrthoDBiEOG7F7WKS.

    Family and domain databases

    InterProiIPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O14259-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSFSSNEYS TEISTEALNN WQQLVEQRIS LELEYAAKLA KLTKSIKAIK    50
    QCAPLNDLTK QVCVELMQCN KKHLEASRYF QTHVKEFMKE YVDRENKFSN 100
    ETISKSSAAA LMTSMENFIL FTNPVYHNKL QVPSKSDMEI ANSLKITQPA 150
    EKNSGTANPI SAYSLEHAEL DERNNQLSEA LSMLRLSPFV NNYYPSYQNR 200
    KDGKSLMENR GVVLSVDTVT SPISQSPKKL TPTTSPINST SLSFVDAKKP 250
    GSKWPSQYDF PKKTKSTEIP FKTLPSLNIN NERELTKHKL PIVKPKLAVF 300
    PSNQATASTL QLAPPPVQAI PTLRNPVNLD DKKESLLKYY ATHPTITPDG 350
    FPIFAYVRAL YAYKATLPSE IDLNVDDTLV VLNRQKDGWW KGLVVSPTVG 400
    RIGLFPSNYI EELEY 415
    Length:415
    Mass (Da):46,782
    Last modified:May 1, 1999 - v2
    Checksum:iF526360B7B9B7946
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16719.2.
    PIRiT39080.
    RefSeqiNP_593857.1. NM_001019286.2.

    Genome annotation databases

    EnsemblFungiiSPAC7D4.02c.1; SPAC7D4.02c.1:pep; SPAC7D4.02c.
    GeneIDi2542091.
    KEGGispo:SPAC7D4.02c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16719.2 .
    PIRi T39080.
    RefSeqi NP_593857.1. NM_001019286.2.

    3D structure databases

    ProteinModelPortali O14259.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 278568. 6 interactions.
    MINTi MINT-4671825.
    STRINGi 4896.SPAC7D4.02c-1.

    Proteomic databases

    MaxQBi O14259.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC7D4.02c.1 ; SPAC7D4.02c.1:pep ; SPAC7D4.02c .
    GeneIDi 2542091.
    KEGGi spo:SPAC7D4.02c.

    Organism-specific databases

    PomBasei SPAC7D4.02c.

    Phylogenomic databases

    eggNOGi NOG303711.
    OMAi ANPISAY.
    OrthoDBi EOG7F7WKS.

    Miscellaneous databases

    NextBioi 20803164.

    Family and domain databases

    InterProi IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
      Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
      Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-221; SER-226; THR-231 AND SER-235, IDENTIFICATION BY MASS SPECTROMETRY.
    4. "A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity."
      Kouranti I., McLean J.R., Feoktistova A., Liang P., Johnson A.E., Roberts-Galbraith R.H., Gould K.L.
      PLoS Biol. 8:708-716(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH UBP4, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION, FUNCTION.

    Entry informationi

    Entry nameiSFP47_SCHPO
    AccessioniPrimary (citable) accession number: O14259
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 77 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3