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O14259

- SFP47_SCHPO

UniProt

O14259 - SFP47_SCHPO

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Protein
Ubp4-interactor sfp47
Gene
sfp47, SPAC7D4.02c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Required for the regulation of activity and recruitment of ubp4 to endosomes.1 Publication

GO - Molecular functioni

  1. protein binding Source: PomBase
Complete GO annotation...

GO - Biological processi

  1. cellular protein localization Source: PomBase
  2. negative regulation of ubiquitin-specific protease activity Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubp4-interactor sfp47
Gene namesi
Name:sfp47
ORF Names:SPAC7D4.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC7D4.02c.

Subcellular locationi

Cytoplasm. Endosome 2 Publications

GO - Cellular componenti

  1. cytoplasm Source: PomBase
  2. cytosol Source: PomBase
  3. endosome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Endosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 415415Ubp4-interactor sfp47
PRO_0000303943Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei221 – 2211Phosphoserine1 Publication
Modified residuei226 – 2261Phosphoserine1 Publication
Modified residuei231 – 2311Phosphothreonine1 Publication
Modified residuei235 – 2351Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO14259.

Interactioni

Subunit structurei

Interacts with ubp4.1 Publication

Protein-protein interaction databases

BioGridi278568. 6 interactions.
MINTiMINT-4671825.
STRINGi4896.SPAC7D4.02c-1.

Structurei

3D structure databases

ProteinModelPortaliO14259.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini352 – 41564SH3
Add
BLAST

Sequence similaritiesi

Contains 1 SH3 domain.

Keywords - Domaini

SH3 domain

Phylogenomic databases

eggNOGiNOG303711.
OMAiANPISAY.
OrthoDBiEOG7F7WKS.

Family and domain databases

InterProiIPR001452. SH3_domain.
[Graphical view]
PfamiPF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O14259-1 [UniParc]FASTAAdd to Basket

« Hide

MNSFSSNEYS TEISTEALNN WQQLVEQRIS LELEYAAKLA KLTKSIKAIK    50
QCAPLNDLTK QVCVELMQCN KKHLEASRYF QTHVKEFMKE YVDRENKFSN 100
ETISKSSAAA LMTSMENFIL FTNPVYHNKL QVPSKSDMEI ANSLKITQPA 150
EKNSGTANPI SAYSLEHAEL DERNNQLSEA LSMLRLSPFV NNYYPSYQNR 200
KDGKSLMENR GVVLSVDTVT SPISQSPKKL TPTTSPINST SLSFVDAKKP 250
GSKWPSQYDF PKKTKSTEIP FKTLPSLNIN NERELTKHKL PIVKPKLAVF 300
PSNQATASTL QLAPPPVQAI PTLRNPVNLD DKKESLLKYY ATHPTITPDG 350
FPIFAYVRAL YAYKATLPSE IDLNVDDTLV VLNRQKDGWW KGLVVSPTVG 400
RIGLFPSNYI EELEY 415
Length:415
Mass (Da):46,782
Last modified:May 1, 1999 - v2
Checksum:iF526360B7B9B7946
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16719.2.
PIRiT39080.
RefSeqiNP_593857.1. NM_001019286.2.

Genome annotation databases

EnsemblFungiiSPAC7D4.02c.1; SPAC7D4.02c.1:pep; SPAC7D4.02c.
GeneIDi2542091.
KEGGispo:SPAC7D4.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16719.2 .
PIRi T39080.
RefSeqi NP_593857.1. NM_001019286.2.

3D structure databases

ProteinModelPortali O14259.
ModBasei Search...

Protein-protein interaction databases

BioGridi 278568. 6 interactions.
MINTi MINT-4671825.
STRINGi 4896.SPAC7D4.02c-1.

Proteomic databases

MaxQBi O14259.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC7D4.02c.1 ; SPAC7D4.02c.1:pep ; SPAC7D4.02c .
GeneIDi 2542091.
KEGGi spo:SPAC7D4.02c.

Organism-specific databases

PomBasei SPAC7D4.02c.

Phylogenomic databases

eggNOGi NOG303711.
OMAi ANPISAY.
OrthoDBi EOG7F7WKS.

Miscellaneous databases

NextBioi 20803164.

Family and domain databases

InterProi IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00018. SH3_1. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
PROSITEi PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-221; SER-226; THR-231 AND SER-235, IDENTIFICATION BY MASS SPECTROMETRY.
  4. "A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity."
    Kouranti I., McLean J.R., Feoktistova A., Liang P., Johnson A.E., Roberts-Galbraith R.H., Gould K.L.
    PLoS Biol. 8:708-716(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH UBP4, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION, FUNCTION.

Entry informationi

Entry nameiSFP47_SCHPO
AccessioniPrimary (citable) accession number: O14259
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 1999
Last modified: July 9, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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