Skip Header

Contribute Send feedback
Read comments (?) or add your own

O14259 (SFP47_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubp4-interactor sfp47
Gene names
Name:sfp47
ORF Names:SPAC7D4.02c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for the regulation of activity and recruitment of ubp4 to endosomes. Ref.4

Subunit structure

Interacts with ubp4. Ref.4

Subcellular location

Cytoplasm. Endosome Ref.2 Ref.4.

Sequence similarities

Contains 1 SH3 domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Cellular componentCytoplasm
Endosome
   DomainSH3 domain
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellular protein localization

Inferred from mutant phenotype Ref.4. Source: PomBase

negative regulation of ubiquitin-specific protease activity

Inferred from mutant phenotype Ref.4. Source: PomBase

   Cellular_componentcytosol

Inferred from direct assay Ref.2. Source: PomBase

endosome

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 415415Ubp4-interactor sfp47
PRO_0000303943

Regions

Domain352 – 41564SH3

Amino acid modifications

Modified residue2211Phosphoserine Ref.3
Modified residue2261Phosphoserine Ref.3
Modified residue2311Phosphothreonine Ref.3
Modified residue2351Phosphoserine Ref.3

Sequences

Sequence LengthMass (Da)Tools
O14259 [UniParc].

Last modified May 1, 1999. Version 2.
Checksum: F526360B7B9B7946

FASTA41546,782
        10         20         30         40         50         60 
MNSFSSNEYS TEISTEALNN WQQLVEQRIS LELEYAAKLA KLTKSIKAIK QCAPLNDLTK 

        70         80         90        100        110        120 
QVCVELMQCN KKHLEASRYF QTHVKEFMKE YVDRENKFSN ETISKSSAAA LMTSMENFIL 

       130        140        150        160        170        180 
FTNPVYHNKL QVPSKSDMEI ANSLKITQPA EKNSGTANPI SAYSLEHAEL DERNNQLSEA 

       190        200        210        220        230        240 
LSMLRLSPFV NNYYPSYQNR KDGKSLMENR GVVLSVDTVT SPISQSPKKL TPTTSPINST 

       250        260        270        280        290        300 
SLSFVDAKKP GSKWPSQYDF PKKTKSTEIP FKTLPSLNIN NERELTKHKL PIVKPKLAVF 

       310        320        330        340        350        360 
PSNQATASTL QLAPPPVQAI PTLRNPVNLD DKKESLLKYY ATHPTITPDG FPIFAYVRAL 

       370        380        390        400        410 
YAYKATLPSE IDLNVDDTLV VLNRQKDGWW KGLVVSPTVG RIGLFPSNYI EELEY

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[3]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-221; SER-226; THR-231 AND SER-235, MASS SPECTROMETRY.
[4]"A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity."
Kouranti I., McLean J.R., Feoktistova A., Liang P., Johnson A.E., Roberts-Galbraith R.H., Gould K.L.
PLoS Biol. 8:0-0(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH UBP4, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION, FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329670 Genomic DNA. Translation: CAB16719.2.
PIRT39080.
RefSeqNP_593857.1. NM_001019286.2.

3D structure databases

HSSPHSSP built from PDB template 2D1X based on UniProtKB Q14247.
ProteinModelPortalO14259.
ModBaseSearch...

Protein-protein interaction databases

STRING4896.SPAC7D4.02c-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC7D4.02c.1; SPAC7D4.02c.1:pep; SPAC7D4.02c.
GeneID2542091.
KEGGspo:SPAC7D4.02c.

Organism-specific databases

PomBaseSPAC7D4.02c.

Phylogenomic databases

eggNOGNOG303711.
OrthoDBEOG46T6BX.

Family and domain databases

InterProIPR001060. FCH_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamPF00611. FCH. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SH3. 1 hit.
PROSITEPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20803164.

Entry information

Entry nameSFP47_SCHPO
AccessionPrimary (citable) accession number: O14259
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 1999
Last modified: May 1, 2013
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents