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Protein

Metallothionein expression activator

Gene

ace2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulates the transcription of genes required for cell separation.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri443 – 472C2H2-type 1PROSITE-ProRule annotationAdd BLAST30
Zinc fingeri473 – 500C2H2-type 2PROSITE-ProRule annotationAdd BLAST28
Zinc fingeri501 – 524C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • RNA polymerase II proximal promoter sequence-specific DNA binding Source: PomBase
  • transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein expression activator
Gene namesi
Name:ace2
ORF Names:SPAC6G10.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC6G10.12c
PomBaseiSPAC6G10.12c ace2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000467991 – 533Metallothionein expression activatorAdd BLAST533

Proteomic databases

PaxDbiO14258
PRIDEiO14258

PTM databases

iPTMnetiO14258

Interactioni

Protein-protein interaction databases

BioGridi278157, 132 interactors
IntActiO14258, 1 interactor
MINTiO14258
STRINGi4896.SPAC6G10.12c.1

Structurei

3D structure databases

ProteinModelPortaliO14258
SMRiO14258
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri443 – 472C2H2-type 1PROSITE-ProRule annotationAdd BLAST30
Zinc fingeri473 – 500C2H2-type 2PROSITE-ProRule annotationAdd BLAST28
Zinc fingeri501 – 524C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

InParanoidiO14258
KOiK09238
OrthoDBiEOG092C2Q0K
PhylomeDBiO14258

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 2 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

Sequencei

Sequence statusi: Complete.

O14258-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSYLSSSS QKSFESFRQE ESPACNHSYQ RDYETFGDSK HTSFSSFAPF
60 70 80 90 100
ENEVSLNQAV IPSPPSHLQN FQDQFDYSSV LKTPFNPLLE ANSAYFLSNQ
110 120 130 140 150
ISLPDSHSYA SSFDASLSPP SSPLTCVSQI HTEQNFNNND AFSLTNSQQA
160 170 180 190 200
FSEIGYDASN WIDELDSQQQ VLSFPEFDIP EIKTETCSNK DHLENFDYLS
210 220 230 240 250
SSIPETSGPA SSVLPSSSQL ESFNEFMFLP SSPPGLDEIN GAPSFEELNF
260 270 280 290 300
QISQPSPAHP VDLSSPETAP NISPVSPFAQ LVKLEPTSPQ KPSFALDSSF
310 320 330 340 350
SHLDVCRHTD NQKAFAKLSS PAEYVSEFEK FSSVCDHGLD ISNANINNTL
360 370 380 390 400
TQQFALSAPY ESCIVTKKPE PCITVKEEEQ LAPKIESADL SITPQVTEHD
410 420 430 440 450
SKPPVRISYD HRCKTRKQST RICRIPPETM ASLYCGPEAD GKYVCLYNGC
460 470 480 490 500
NKRIARKYNV ESHIQTHLSD RPYRCDLCKA GFVRHHDLKR HLRIHENGRP
510 520 530
YVCECLKRFN RLDALNRHKQ RNICVGGVDR RQH
Length:533
Mass (Da):59,842
Last modified:January 1, 1998 - v1
Checksum:iA352F632746E7001
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11298.1
PIRiT39062
RefSeqiNP_594109.1, NM_001019533.2

Genome annotation databases

EnsemblFungiiSPAC6G10.12c.1; SPAC6G10.12c.1:pep; SPAC6G10.12c
GeneIDi2541661
KEGGispo:SPAC6G10.12c

Entry informationi

Entry nameiACE2_SCHPO
AccessioniPrimary (citable) accession number: O14258
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

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