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Protein

probable cardiolipin-specific deacylase, mitochondrial

Gene

SPAC6G10.03c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Mitochondrial cardiolipin-specific phospholipase which deacylates de novo synthesized cardiolipin. Part of the remodeling process of cardiolipin, which involves deacylation-reacylation of premature cardiolipin (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

ReactomeiR-SPO-1482839 Acyl chain remodelling of PE

Protein family/group databases

ESTHERischpo-ye63 CGI-58_ABHD5_ABHD4

Names & Taxonomyi

Protein namesi
Recommended name:
probable cardiolipin-specific deacylase, mitochondrial (EC:3.5.1.-)
Gene namesi
ORF Names:SPAC6G10.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC6G10.03c
PomBaseiSPAC6G10.03c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000116702? – 428probable cardiolipin-specific deacylase, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiO14249
PaxDbiO14249
PRIDEiO14249

Interactioni

Protein-protein interaction databases

STRINGi4896.SPAC6G10.03c.1

Structurei

3D structure databases

ProteinModelPortaliO14249
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 217AB hydrolase-1Sequence analysisAdd BLAST125

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi398 – 403HXXXXD motifBy similarity6

Domaini

The HXXXXD motif is essential for acyltransferase activity.By similarity

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000211778
InParanoidiO14249
KOiK13535
OMAiGWSPFQV
OrthoDBiEOG092C2HX9
PhylomeDBiO14249

Family and domain databases

InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
SUPFAMiSSF53474 SSF53474, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O14249-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQVKVAVRS EEAANSYTQT FGMSWRQWRQ ACSEEYAKQC EREVLHTVDF
60 70 80 90 100
IRENEKDPER LVEVVDSKIY DNDGLVHEVC VSDKATGKAN KRSIVYMHGY
110 120 130 140 150
GAGLGFYFRN MDGLTKGVTK DFNSYFVDWL GMGNSSRPPF DIKGQTASEK
160 170 180 190 200
VEETERFFTE SLETWRIGHG IEKMILVGHS MGGYLSAVYA MQYPERVEKL
210 220 230 240 250
LLVSPVAIPE NPFASNDDAE VYNSVASSAV HAVMDEPPLS NVTNEVLQTQ
260 270 280 290 300
EETTGLEPSR PSKPKNPLPR FITFLWEQNV TPFSLLRLSG PLGPKLMSFW
310 320 330 340 350
SSRRFSTLPP ETFRALHNYC YSIFRLKGSS EYALGNLLAP GAFARRCIMN
360 370 380 390 400
RLRMLKCRTI FMYGDKDWMD DVAGLEATNR LKEMNIEAEH HIISNAGHHC
410 420
YLDNPEDFNE IVLKEIRMSL RSFSSISE
Length:428
Mass (Da):48,720
Last modified:January 1, 1998 - v1
Checksum:iEDB60B76D0F6B4CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11289.1
PIRiT39053
RefSeqiNP_594100.1, NM_001019524.2

Genome annotation databases

EnsemblFungiiSPAC6G10.03c.1; SPAC6G10.03c.1:pep; SPAC6G10.03c
GeneIDi2542281
KEGGispo:SPAC6G10.03c

Similar proteinsi

Entry informationi

Entry nameiCLD1_SCHPO
AccessioniPrimary (citable) accession number: O14249
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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