Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O14234

- CCH1_SCHPO

UniProt

O14234 - CCH1_SCHPO

Protein

Calcium-channel protein cch1

Gene

cch1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Voltage-gated, high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones. Functions together with yam8 to ensure that adequate levels of Ca2+ are supplied to pmr1 to sustain secretion and growth. Required for growth in low-calcium environments By similarity.By similarity

    GO - Molecular functioni

    1. calcium channel activity Source: PomBase
    2. voltage-gated calcium channel activity Source: InterPro

    GO - Biological processi

    1. positive regulation of calcium-mediated signaling Source: PomBase
    2. positive regulation of phosphoprotein phosphatase activity Source: PomBase

    Keywords - Molecular functioni

    Calcium channel, Ion channel, Voltage-gated channel

    Keywords - Biological processi

    Calcium transport, Ion transport, Transport

    Keywords - Ligandi

    Calcium

    Protein family/group databases

    TCDBi1.A.1.11.23. the voltage-gated ion channel (vic) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Calcium-channel protein cch1
    Gene namesi
    Name:cch1
    ORF Names:SPAC6F6.01
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC6F6.01.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: PomBase
    2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    3. integral component of plasma membrane Source: PomBase
    4. voltage-gated calcium channel complex Source: InterPro

    Keywords - Cellular componenti

    Cell membrane, Endoplasmic reticulum, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 18541854Calcium-channel protein cch1PRO_0000311769Add
    BLAST

    Proteomic databases

    MaxQBiO14234.

    Interactioni

    Subunit structurei

    Interacts with yam8 to form a Ca2+ influx channel.By similarity

    Protein-protein interaction databases

    BioGridi279259. 33 interactions.
    MINTiMINT-4671635.
    STRINGi4896.SPAC6F6.01-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO14234.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei184 – 20421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei220 – 24021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei274 – 29421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei328 – 34821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei427 – 44721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei461 – 48121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei514 – 53421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei549 – 56921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei581 – 60121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei606 – 62621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei642 – 66221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei723 – 74321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei946 – 96621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei980 – 100021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1021 – 104121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1075 – 109521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1148 – 116821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1193 – 121321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1274 – 129421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1302 – 132221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1331 – 135121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1358 – 137821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1393 – 141321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1486 – 150621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG268129.
    OMAiLALVEWK.
    OrthoDBiEOG7Z69MN.
    PhylomeDBiO14234.

    Family and domain databases

    Gene3Di1.20.120.350. 1 hit.
    InterProiIPR027359. Channel_four-helix_dom.
    IPR005821. Ion_trans_dom.
    IPR002077. VDCCAlpha1.
    [Graphical view]
    PfamiPF00520. Ion_trans. 4 hits.
    [Graphical view]
    PRINTSiPR00167. CACHANNEL.

    Sequencei

    Sequence statusi: Complete.

    O14234-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSSSNSDPS SSPDNTDFIP LKDNPKDTSS YINKKNPFVN DSFDSHDDSY     50
    LDNVNPFEYN VADDEDTISM TSDGVEFHNL GITETVDEQD KILSELQLAY 100
    PTVSRYSETL DKGLLNGDKT TKGDYTSLRR FRKPFLFDKL SPYFTHFFSE 150
    IYAAVLRVVG PPRANETPGR NLPFSPILRQ IYNHPLYNIF IFVVIVLHAV 200
    LLMIRSDDPH DKSQTIDYLI IVIGILYTLE MLLKIYLFGF LYDGSSSFYD 250
    FINSYTKKTP RTMSYLRHSW NRVDFVAIVA LWISVIGKKQ QGIFRLFSMI 300
    ACLRLTRLLN ITRKTETILK SLKESSTPLV QVVSFNAFFG VMIAILGVQF 350
    FKASLNRQCV WLGDYGDQYL PTGQFCGGHW ENGIKRAYLD KNGFPSNVNP 400
    RGFICAEKSV CRVVENPYSN TVSFDNFFNS LELIFVIMSS NGFTDIMYDI 450
    MDAEYFVSCL LFIISAYFLT LWLMSLVIAV VTSSFIDLQH SGKNQKEQKS 500
    VDKHLIRNKL CEKYLFYSNF IWISFIVAQF VTLCTQTYDQ TSSTANRYLI 550
    FYACVDFLLA AEVILRFFAY LPDYRLFFRR YTNLVDIVLA VLNLVTLLPS 600
    IRKNPVAFGW LSIFAIARIY RCILLIPYTR KIAKLLFSNF KQLLNLMLFL 650
    VIVLFIASLC AVRLFQDLPN DGDSDDDAIS FATTYESFLY MYQILTSENW 700
    TDVMFAIQAR LAHLHLSWIP GAFFTLWFLF SNNVVLSMFI AVIQVNFAPS 750
    ESDLKMEQLK MYLARLLRNY NPFQASLTLN ALIKRNGSRK GKTVDESHYE 800
    WLYEDNIIKG FLRVTNIPPK EPLKPSLDTS PELSKYSLAK LSNNFKRFVM 850
    RDDPFSQAYF KRVIGIRWEK DMNLKTAAKD MQAAKAFVRI KQTEFLKNHP 900
    KYNDVFWVIK PSNRIRRFCQ RLVMPGVNER YGGVEPYQWV YRVIQVFIYA 950
    CILTAVIIEC IATPIYERDH LLNDKQHAWF VWTEVAFATI FTIEAAIKII 1000
    ADGFCITPNA YLRSTWNCID FFVLVTLWIN LYAVLTSHAL LSRAFRAFKA 1050
    LRVLRLINLT QTSQRMFHDA LISGFFKIFS AAVVSATLLI PFALWAKNVF 1100
    GGLLYSCNDD NVLSASQCVL EYASTPNNWE VWAPRVWSNP PDYDFDRFPH 1150
    ALLALFEIAS IEGWVDIMRS VMDITGFNNQ PQTNASSGNA MFFVLFNLVS 1200
    MIYILTLFIA IIISNYAERT GSAFFTAEQR AWLELRRKIK SMRPSKRPAI 1250
    RPLGLRGLCY DFAVQKHGIW RRTFTGLYIV HLLFLLTIFY PCPIAYTYVR 1300
    NSIFLILSIC YTINICVKVY GLSFYYFFHS FWNMFDVVVT LGSLTCNIAI 1350
    LAKFENRSLT LLQTTLLVLV TVHLIPKFDN FDQLSKTVVA SLPSIFSLIA 1400
    TWIVLYITFA IAFNQIFGLT KLGLNGGPNK NFRSIRNALV LLFTMTFGEG 1450
    WNDVMHDYTI SYPNCVNGDD FYNSDCGNKP WAYGLFIAWN IISMYIFVNM 1500
    FITVVFDNFS YIHTKSSSFT NLQRNDFRQF KDSWAPFDPM VTGYIPKRNA 1550
    VKFVLSLRGV YDFRIYRDEH TLRSIISKVQ SKTGQQSVPM LENPLMGSEI 1600
    NLEALDQIID TIDVNVVKER RNVLNSLCTE IMTLPGNVIS FSNILMLVVL 1650
    HKIVDHREAF PISDYIRRAY VLSELEKSIR MEKLLGLVET SIIRKTFLQH 1700
    MEEKKKALEN PFILLSEVSE ILPETPIQEV LRQHNADPEQ LLMSTRTPSV 1750
    SDRSFSIVES TVPTIASGEG DDNHSVEDHL KVPTDNEPRR SPSLKEVLLR 1800
    GSHSLHSNND RTSFDIEAGF GTAESDFQFG GATEDINRIA DRIDDYLDRD 1850
    SFKG 1854
    Length:1,854
    Mass (Da):213,165
    Last modified:January 1, 1998 - v1
    Checksum:i79C972D54E228DFA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB11726.1.
    PIRiT39035.
    RefSeqiNP_593894.1. NM_001019324.2.

    Genome annotation databases

    EnsemblFungiiSPAC6F6.01.1; SPAC6F6.01.1:pep; SPAC6F6.01.
    GeneIDi2542812.
    KEGGispo:SPAC6F6.01.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB11726.1 .
    PIRi T39035.
    RefSeqi NP_593894.1. NM_001019324.2.

    3D structure databases

    ProteinModelPortali O14234.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 279259. 33 interactions.
    MINTi MINT-4671635.
    STRINGi 4896.SPAC6F6.01-1.

    Protein family/group databases

    TCDBi 1.A.1.11.23. the voltage-gated ion channel (vic) superfamily.

    Proteomic databases

    MaxQBi O14234.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC6F6.01.1 ; SPAC6F6.01.1:pep ; SPAC6F6.01 .
    GeneIDi 2542812.
    KEGGi spo:SPAC6F6.01.

    Organism-specific databases

    PomBasei SPAC6F6.01.

    Phylogenomic databases

    eggNOGi NOG268129.
    OMAi LALVEWK.
    OrthoDBi EOG7Z69MN.
    PhylomeDBi O14234.

    Miscellaneous databases

    NextBioi 20803854.

    Family and domain databases

    Gene3Di 1.20.120.350. 1 hit.
    InterProi IPR027359. Channel_four-helix_dom.
    IPR005821. Ion_trans_dom.
    IPR002077. VDCCAlpha1.
    [Graphical view ]
    Pfami PF00520. Ion_trans. 4 hits.
    [Graphical view ]
    PRINTSi PR00167. CACHANNEL.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
      Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
      Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiCCH1_SCHPO
    AccessioniPrimary (citable) accession number: O14234
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3