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Protein

mRNA export factor elf1

Gene

elf1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Has a direct role in the mRNA export process. Appears to act within the rae1 mediated mRNA export pathway.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi477 – 4848ATP 1PROSITE-ProRule annotation
Nucleotide bindingi726 – 7338ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

  • ATPase activity Source: PomBase
  • ATP binding Source: PomBase

GO - Biological processi

  • mRNA export from nucleus Source: PomBase
  • poly(A)+ mRNA export from nucleus Source: PomBase
  • ribosomal small subunit biogenesis Source: PomBase
Complete GO annotation...

Keywords - Biological processi

mRNA transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
mRNA export factor elf1
Gene namesi
Name:elf1
ORF Names:SPAC3C7.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3C7.08c.
PomBaseiSPAC3C7.08c. elf1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: UniProtKB-SubCell
  • protein complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi731 – 7311G → D: No mRNA transport. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10571057mRNA export factor elf1PRO_0000093460Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei733 – 7331Phosphoserine1 Publication
Modified residuei1041 – 10411Phosphoserine1 Publication
Modified residuei1053 – 10531Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO14134.

PTM databases

iPTMnetiO14134.

Interactioni

Protein-protein interaction databases

BioGridi279515. 10 interactions.
MINTiMINT-4670793.

Structurei

3D structure databases

ProteinModelPortaliO14134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini440 – 659220ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini692 – 1019328ABC transporter 2PROSITE-ProRule annotationAdd
BLAST
Domaini820 – 86950ChromoPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi329 – 33810Poly-Ala

Sequence similaritiesi

Contains 2 ABC transporter domains.PROSITE-ProRule annotation
Contains 1 chromo domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000180957.
InParanoidiO14134.
KOiK03235.
OMAiPKGTPHP.
OrthoDBiEOG092C22OB.
PhylomeDBiO14134.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000953. Chromo/shadow_dom.
IPR023780. Chromo_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 2 hits.
PF00385. Chromo. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
SM00298. CHROMO. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 6 hits.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
PS50013. CHROMO_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O14134-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSVLIQGY EEDDVLKLLQ ELLDAETSQS CADVGKKIAQ LFSNDNPLVT
60 70 80 90 100
LKTTGFLDGL ERAARNKKSG FHREAAMIGF ATVIKNLGTP SEVVFLPYLP
110 120 130 140 150
TILDSFSDRG EVVRQAAKMA AQALLDCLPA GAVETRLIPS LISYLDDSSI
160 170 180 190 200
KWPSKVAALQ LLGSLASSSP KAVADYMAAL IPCIKERMHD TKPEISRAAI
210 220 230 240 250
TCMLNLCSVV ENNDIIPHIP KLVDCMAHPE TLEACIKDLS ATTFVATVES
260 270 280 290 300
VALAVLVPIL KRALAQRSQS MLRLTVIITD NLCKLVPDPA EASDFLPELI
310 320 330 340 350
PDVERIAQTA AMPEVRALAS HALTTLNKAA AAQAAKAANN SEKQALDSAC
360 370 380 390 400
KELREAVLKN TSVPHELANS IIDYVCDALA ALYKSNNFDK DKWTSQLGVL
410 420 430 440 450
YLSPLVGEEL ASQISSKIYD DLHAFYKSLN SVDGISNLTI EEEELVNTDF
460 470 480 490 500
SLAYGGRLLL SHTNLHLYRG HRYGVVGHNG CGKSTLLRAI GDYKVENFPS
510 520 530 540 550
PDEVKTCFVA HSLQGEDTSM AILDFVAQDK ALLTMNVTRQ EAADALHSVG
560 570 580 590 600
FTAEMQENPV ASLSGGWKMK LELARAMLQK ADILLLDEPT NHLDVANIAW
610 620 630 640 650
LEAYLTSQKN ITCLIVSHDS SFLDHVCTDI IHYEGVKNQA KKLGYYQGNL
660 670 680 690 700
SAFVKVKPEA KSYYTLTATN EKFVFPPPGI LTGVRSNTRL ILKMTNASYT
710 720 730 740 750
YPNAKKKSLD NVTVGLSLSS RVAILGPNGA GKSTLIKVLI GEVIPQEGKV
760 770 780 790 800
FKHPNLRVGY VAQHAFHHLD QHLEKTPSQY IQWRYAGGQD REVSEKESRK
810 820 830 840 850
LTEEDRAQLQ RDITVNGERR RVEALIGRQK LKKSFQYEIK WFGKPHKYNT
860 870 880 890 900
WVSREILLEN GFQKFVQAFD DMESSREGLG FRELIPEDIR AHFEDVGLPG
910 920 930 940 950
DIADYSPISS LSGGQKVKVV IAACLWNNPQ LLVLDEPTNF LDRDALGGLA
960 970 980 990 1000
VAIRDWEGGV VMISHNEEFV SALCPEHWHV EAGKVTGKGK TAVDDGKFED
1010 1020 1030 1040 1050
LSEKDLKKIE AKATKKKKLT RNEIKAKERR ARERELAWLQ SPKGTEKPKS

FFSDDEE
Length:1,057
Mass (Da):116,701
Last modified:January 1, 1998 - v1
Checksum:i60DF5AE9DFC9D9F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16738.1.
PIRiT38694.
RefSeqiNP_593609.1. NM_001019040.2.

Genome annotation databases

EnsemblFungiiSPAC3C7.08c.1; SPAC3C7.08c.1:pep; SPAC3C7.08c.
GeneIDi2543082.
KEGGispo:SPAC3C7.08c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16738.1.
PIRiT38694.
RefSeqiNP_593609.1. NM_001019040.2.

3D structure databases

ProteinModelPortaliO14134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279515. 10 interactions.
MINTiMINT-4670793.

PTM databases

iPTMnetiO14134.

Proteomic databases

MaxQBiO14134.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3C7.08c.1; SPAC3C7.08c.1:pep; SPAC3C7.08c.
GeneIDi2543082.
KEGGispo:SPAC3C7.08c.

Organism-specific databases

EuPathDBiFungiDB:SPAC3C7.08c.
PomBaseiSPAC3C7.08c. elf1.

Phylogenomic databases

HOGENOMiHOG000180957.
InParanoidiO14134.
KOiK03235.
OMAiPKGTPHP.
OrthoDBiEOG092C22OB.
PhylomeDBiO14134.

Miscellaneous databases

PROiO14134.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000953. Chromo/shadow_dom.
IPR023780. Chromo_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 2 hits.
PF00385. Chromo. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
SM00298. CHROMO. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 6 hits.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
PS50013. CHROMO_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiELF1_SCHPO
AccessioniPrimary (citable) accession number: O14134
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.