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Protein

Arginyl-tRNA--protein transferase 1

Gene

SPAC3C7.07c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).By similarity

Catalytic activityi

L-arginyl-tRNA(Arg) + [protein] = tRNA(Arg) + L-arginyl-[protein].

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processUbl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Arginyl-tRNA--protein transferase 1 (EC:2.3.2.8)
Short name:
Arginyltransferase 1
Short name:
R-transferase 1
Alternative name(s):
Arginine-tRNA--protein transferase 1
Gene namesi
ORF Names:SPAC3C7.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC3C7.07c
PomBaseiSPAC3C7.07c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003510801 – 391Arginyl-tRNA--protein transferase 1Add BLAST391

Proteomic databases

MaxQBiO14133
PaxDbiO14133

Interactioni

Protein-protein interaction databases

BioGridi279382, 2 interactors
STRINGi4896.SPAC3C7.07c.1

Structurei

3D structure databases

SMRiO14133
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the R-transferase family.Curated

Phylogenomic databases

InParanoidiO14133
KOiK00685
OrthoDBiEOG092C3AJH

Family and domain databases

InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR030700 N-end_Aminoacyl_Trfase
IPR007472 N-end_Aminoacyl_Trfase_C
IPR007471 N-end_Aminoacyl_Trfase_N
PANTHERiPTHR21367 PTHR21367, 2 hits
PfamiView protein in Pfam
PF04377 ATE_C, 1 hit
PF04376 ATE_N, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit

Sequencei

Sequence statusi: Complete.

O14133-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLDKLLYTG YNVSTECGYC KSGRKTEHFG LLAEKLSCED YQRLIDLGWR
60 70 80 90 100
RSGHYLYKPN GKTSCCSLYT IRLDSYNFKI AKEQKKAIKK WVKYVNGKPL
110 120 130 140 150
KPMKSEISTD YLNNAFQTIE SLGAEKYSVT MEPCTYTDEK FEVFKKYQMQ
160 170 180 190 200
VHLEKEEEIT KKGFSRFLCN SPLFNEDKGI KYGSYHQMYR FQGRLVAVGV
210 220 230 240 250
LDLLPHGVSS VYLFYDPDMS KFSLGRISAC REIWLALECG YRYYYMGYYI
260 270 280 290 300
HTCPKMKYKA TYSPSYLLNP GTNKWIPIEN FTSLWNTGAP KYISFGDENN
310 320 330 340 350
SDIQTAVDYD SSEDSSQNED DYTLFNRQLP GILSVNVAES LVSENFANIG
360 370 380 390
NSTFPTRHVL SYFPQVKHWF VEINAAVGEE VAKSYTLVLS S
Length:391
Mass (Da):45,092
Last modified:April 18, 2012 - v3
Checksum:i68CA0F88F243E9DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16746.2
PIRiT38693
RefSeqiNP_593608.2, NM_001019039.2

Genome annotation databases

EnsemblFungiiSPAC3C7.07c.1; SPAC3C7.07c.1:pep; SPAC3C7.07c
GeneIDi2542941
KEGGispo:SPAC3C7.07c

Similar proteinsi

Entry informationi

Entry nameiATE1_SCHPO
AccessioniPrimary (citable) accession number: O14133
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: April 18, 2012
Last modified: March 28, 2018
This is version 90 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health