Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O14120

- MVP1_SCHPO

UniProt

O14120 - MVP1_SCHPO

Protein

Sorting nexin mvp1

Gene

mvp1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 3 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for vacuolar protein sorting.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei320 – 3201Phosphatidylinositol 3-phosphateBy similarity
    Binding sitei322 – 3221Phosphatidylinositol 3-phosphate; via amide nitrogen and carbonyl oxygenBy similarity
    Binding sitei346 – 3461Phosphatidylinositol 3-phosphateBy similarity

    GO - Molecular functioni

    1. phosphatidylinositol-3-phosphate binding Source: PomBase

    GO - Biological processi

    1. protein targeting to vacuole Source: PomBase

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sorting nexin mvp1
    Gene namesi
    Name:mvp1
    ORF Names:SPAC3A11.06
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC3A11.06.

    Subcellular locationi

    Cytoplasm By similarity. Membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity

    GO - Cellular componenti

    1. fungal-type vacuole membrane Source: PomBase
    2. Golgi apparatus Source: PomBase

    Keywords - Cellular componenti

    Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 664664Sorting nexin mvp1PRO_0000238601Add
    BLAST

    Proteomic databases

    MaxQBiO14120.

    Interactioni

    Protein-protein interaction databases

    BioGridi279556. 16 interactions.
    MINTiMINT-4670637.
    STRINGi4896.SPAC3A11.06-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO14120.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini279 – 395117PXPROSITE-ProRule annotationAdd
    BLAST

    Domaini

    The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.By similarity

    Sequence similaritiesi

    Belongs to the sorting nexin family.Curated
    Contains 1 PX (phox homology) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG5391.
    KOiK17922.
    OrthoDBiEOG7B320H.
    PhylomeDBiO14120.

    Family and domain databases

    Gene3Di3.30.1520.10. 1 hit.
    InterProiIPR001683. Phox.
    [Graphical view]
    PfamiPF00787. PX. 1 hit.
    [Graphical view]
    SMARTiSM00312. PX. 1 hit.
    [Graphical view]
    SUPFAMiSSF64268. SSF64268. 1 hit.
    PROSITEiPS50195. PX. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O14120-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGDNVFLEPD PWASSSNWGS PVKPLNYKTA IGNSSIPLQY RNYWDVFQAN    50
    NVLLFPEEES YSDIFHVPQD VMKEFFTLIE SSSNQPLRQI QFFVLLALVA 100
    CYQLGVPSTL EQIFKQRNVL PILQRFNPEL FNRSSDNETP LFPNNSPPAS 150
    TTALNLSSNI VPSINESKIL EQEDDDVSNK SLPHAQQSII RSFPDIQKQP 200
    KGFFSYPSST VSSIAPSTLE AGNLHSQQPP KFSVDSSVDD NAITPRKPFS 250
    KIPNRLSPST QPLLSNSRHS SFRLASSSTS FPASLEMNVD IDLEPSGYFF 300
    YRHNNYIISD SSNTREVLRR YSDFFWLHSY LMKKYPFRRV PLIPLKKFHS 350
    KCFNSKQFFR TPPPGLSDFV NDLSHHPIFS NDEVVRVFFT EPNVFKNWRR 400
    ENQKRIDQEI EQFLVVPQSQ VPDASETVKE RLLKLNMSTT TAINNQLNIF 450
    RIFEKMIFTL QHFHEDFLRL QNSFNCLLDS GLYHQVFTST FAQNESKIMS 500
    MASGHFYNID SLLHQQNDAV KHTFLLGLSK EIKILISLRL LIERISEVFS 550
    TDLTKVRHTI SNDENLLRET ANSDESGRNR TFLNRSSKKR AENSLKSKKE 600
    LYLKNLNQRY QIAHELEQEL SYLQDYVFSL GNPYVEYCKQ HVKLEEESLK 650
    IWHTLESDFS RLET 664
    Length:664
    Mass (Da):76,861
    Last modified:May 1, 2000 - v3
    Checksum:iFB4E9F1C312FA85C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16392.2.
    PIRiT11628.
    RefSeqiNP_594197.1. NM_001019621.2.

    Genome annotation databases

    EnsemblFungiiSPAC3A11.06.1; SPAC3A11.06.1:pep; SPAC3A11.06.
    GeneIDi2543124.
    KEGGispo:SPAC3A11.06.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16392.2 .
    PIRi T11628.
    RefSeqi NP_594197.1. NM_001019621.2.

    3D structure databases

    ProteinModelPortali O14120.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 279556. 16 interactions.
    MINTi MINT-4670637.
    STRINGi 4896.SPAC3A11.06-1.

    Proteomic databases

    MaxQBi O14120.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC3A11.06.1 ; SPAC3A11.06.1:pep ; SPAC3A11.06 .
    GeneIDi 2543124.
    KEGGi spo:SPAC3A11.06.

    Organism-specific databases

    PomBasei SPAC3A11.06.

    Phylogenomic databases

    eggNOGi COG5391.
    KOi K17922.
    OrthoDBi EOG7B320H.
    PhylomeDBi O14120.

    Miscellaneous databases

    NextBioi 20804151.

    Family and domain databases

    Gene3Di 3.30.1520.10. 1 hit.
    InterProi IPR001683. Phox.
    [Graphical view ]
    Pfami PF00787. PX. 1 hit.
    [Graphical view ]
    SMARTi SM00312. PX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF64268. SSF64268. 1 hit.
    PROSITEi PS50195. PX. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiMVP1_SCHPO
    AccessioniPrimary (citable) accession number: O14120
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 77 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3