Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O14120

- MVP1_SCHPO

UniProt

O14120 - MVP1_SCHPO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Sorting nexin mvp1

Gene

mvp1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Required for vacuolar protein sorting.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei320 – 3201Phosphatidylinositol 3-phosphateBy similarity
Binding sitei322 – 3221Phosphatidylinositol 3-phosphate; via amide nitrogen and carbonyl oxygenBy similarity
Binding sitei346 – 3461Phosphatidylinositol 3-phosphateBy similarity

GO - Molecular functioni

  1. phosphatidylinositol-3-phosphate binding Source: PomBase

GO - Biological processi

  1. protein targeting to vacuole Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sorting nexin mvp1
Gene namesi
Name:mvp1
ORF Names:SPAC3A11.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC3A11.06.

Subcellular locationi

Cytoplasm By similarity. Membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity

GO - Cellular componenti

  1. fungal-type vacuole membrane Source: PomBase
  2. Golgi apparatus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 664664Sorting nexin mvp1PRO_0000238601Add
BLAST

Proteomic databases

MaxQBiO14120.

Interactioni

Protein-protein interaction databases

BioGridi279556. 16 interactions.
MINTiMINT-4670637.
STRINGi4896.SPAC3A11.06-1.

Structurei

3D structure databases

ProteinModelPortaliO14120.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini279 – 395117PXPROSITE-ProRule annotationAdd
BLAST

Domaini

The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization.By similarity

Sequence similaritiesi

Belongs to the sorting nexin family.Curated
Contains 1 PX (phox homology) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG5391.
InParanoidiO14120.
KOiK17922.
OrthoDBiEOG7B320H.
PhylomeDBiO14120.

Family and domain databases

Gene3Di3.30.1520.10. 1 hit.
InterProiIPR001683. Phox.
[Graphical view]
PfamiPF00787. PX. 1 hit.
[Graphical view]
SMARTiSM00312. PX. 1 hit.
[Graphical view]
SUPFAMiSSF64268. SSF64268. 1 hit.
PROSITEiPS50195. PX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O14120-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGDNVFLEPD PWASSSNWGS PVKPLNYKTA IGNSSIPLQY RNYWDVFQAN
60 70 80 90 100
NVLLFPEEES YSDIFHVPQD VMKEFFTLIE SSSNQPLRQI QFFVLLALVA
110 120 130 140 150
CYQLGVPSTL EQIFKQRNVL PILQRFNPEL FNRSSDNETP LFPNNSPPAS
160 170 180 190 200
TTALNLSSNI VPSINESKIL EQEDDDVSNK SLPHAQQSII RSFPDIQKQP
210 220 230 240 250
KGFFSYPSST VSSIAPSTLE AGNLHSQQPP KFSVDSSVDD NAITPRKPFS
260 270 280 290 300
KIPNRLSPST QPLLSNSRHS SFRLASSSTS FPASLEMNVD IDLEPSGYFF
310 320 330 340 350
YRHNNYIISD SSNTREVLRR YSDFFWLHSY LMKKYPFRRV PLIPLKKFHS
360 370 380 390 400
KCFNSKQFFR TPPPGLSDFV NDLSHHPIFS NDEVVRVFFT EPNVFKNWRR
410 420 430 440 450
ENQKRIDQEI EQFLVVPQSQ VPDASETVKE RLLKLNMSTT TAINNQLNIF
460 470 480 490 500
RIFEKMIFTL QHFHEDFLRL QNSFNCLLDS GLYHQVFTST FAQNESKIMS
510 520 530 540 550
MASGHFYNID SLLHQQNDAV KHTFLLGLSK EIKILISLRL LIERISEVFS
560 570 580 590 600
TDLTKVRHTI SNDENLLRET ANSDESGRNR TFLNRSSKKR AENSLKSKKE
610 620 630 640 650
LYLKNLNQRY QIAHELEQEL SYLQDYVFSL GNPYVEYCKQ HVKLEEESLK
660
IWHTLESDFS RLET
Length:664
Mass (Da):76,861
Last modified:May 1, 2000 - v3
Checksum:iFB4E9F1C312FA85C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16392.2.
PIRiT11628.
RefSeqiNP_594197.1. NM_001019621.2.

Genome annotation databases

EnsemblFungiiSPAC3A11.06.1; SPAC3A11.06.1:pep; SPAC3A11.06.
GeneIDi2543124.
KEGGispo:SPAC3A11.06.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAB16392.2 .
PIRi T11628.
RefSeqi NP_594197.1. NM_001019621.2.

3D structure databases

ProteinModelPortali O14120.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 279556. 16 interactions.
MINTi MINT-4670637.
STRINGi 4896.SPAC3A11.06-1.

Proteomic databases

MaxQBi O14120.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC3A11.06.1 ; SPAC3A11.06.1:pep ; SPAC3A11.06 .
GeneIDi 2543124.
KEGGi spo:SPAC3A11.06.

Organism-specific databases

PomBasei SPAC3A11.06.

Phylogenomic databases

eggNOGi COG5391.
InParanoidi O14120.
KOi K17922.
OrthoDBi EOG7B320H.
PhylomeDBi O14120.

Miscellaneous databases

NextBioi 20804151.

Family and domain databases

Gene3Di 3.30.1520.10. 1 hit.
InterProi IPR001683. Phox.
[Graphical view ]
Pfami PF00787. PX. 1 hit.
[Graphical view ]
SMARTi SM00312. PX. 1 hit.
[Graphical view ]
SUPFAMi SSF64268. SSF64268. 1 hit.
PROSITEi PS50195. PX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiMVP1_SCHPO
AccessioniPrimary (citable) accession number: O14120
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 78 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3