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Protein

Putative exopolyphosphatase

Gene

SPAC2F3.11

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Degradation of inorganic polyphosphates.By similarity

Catalytic activityi

(Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

Cofactori

Mn2+CuratedNote: Binds 2 manganese ions per subunit.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi40Manganese 1By similarity1
Metal bindingi42Manganese 2By similarity1
Metal bindingi116Manganese 1By similarity1
Metal bindingi116Manganese 2By similarity1
Metal bindingi138Manganese 2By similarity1
Metal bindingi200Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative exopolyphosphatase (EC:3.6.1.11)
Short name:
ExopolyPase
Alternative name(s):
Metaphosphatase
Gene namesi
ORF Names:SPAC2F3.11
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC2F3.11
PomBaseiSPAC2F3.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001586001 – 384Putative exopolyphosphataseAdd BLAST384

Proteomic databases

MaxQBiO14094
PaxDbiO14094
PRIDEiO14094

PTM databases

iPTMnetiO14094

Interactioni

Protein-protein interaction databases

BioGridi278344, 44 interactors
STRINGi4896.SPAC2F3.11.1

Structurei

3D structure databases

ProteinModelPortaliO14094
SMRiO14094
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPase class C family.Curated

Phylogenomic databases

InParanoidiO14094
KOiK01514
OMAiIYMDLEA
OrthoDBiEOG092C2PKQ
PhylomeDBiO14094

Family and domain databases

Gene3Di3.10.310.20, 1 hit
InterProiView protein in InterPro
IPR001667 DDH_dom
IPR004097 DHHA2
IPR038222 DHHA2_dom_sf
PfamiView protein in Pfam
PF01368 DHH, 1 hit
PF02833 DHHA2, 1 hit
SMARTiView protein in SMART
SM01131 DHHA2, 1 hit

Sequencei

Sequence statusi: Complete.

O14094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLGRFLENG REQIRNLLLN ASTVSSAPSF SFVSGNESAD LDSCASSIVY
60 70 80 90 100
AYCLQRKQLG RIVVPFFNIP RKELRLRPEL SYLLNLASIS SDDIVFLDDI
110 120 130 140 150
VKLPKRIFSN PIYLVDHNSL DRKDLENFNG SIAGIIDHHK DEGGSLHADP
160 170 180 190 200
RIIEECGSCC TLVCRYFMPV IRSLYDSKVS ELHQTATNLA VLALGPILID
210 220 230 240 250
TGNLKNEKTT DTDVKIVNDL CSFVPKDWVR DEFFDTLKEK KKSCKGFSFD
260 270 280 290 300
DLLRRDLKQY FPDGIVVNYA SVGKGLDWIK KKRLGWEDEL KSFAEVQNSD
310 320 330 340 350
LVIVGLSLSK NDEFGRQLIL YKRTERGAGL ADSFLKLSKQ NLGLEIIEEK
360 370 380
DNGDLSMWNQ RNSAASRKKV VPLLMDSVKQ VASK
Length:384
Mass (Da):43,297
Last modified:January 1, 1998 - v1
Checksum:i643CC43C7AF185EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16267.1
PIRiT38544
RefSeqiNP_594390.1, NM_001019812.2

Genome annotation databases

EnsemblFungiiSPAC2F3.11.1; SPAC2F3.11.1:pep; SPAC2F3.11
GeneIDi2541853
KEGGispo:SPAC2F3.11

Similar proteinsi

Entry informationi

Entry nameiPPX1_SCHPO
AccessioniPrimary (citable) accession number: O14094
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health