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O14094

- PPX1_SCHPO

UniProt

O14094 - PPX1_SCHPO

Protein

Putative exopolyphosphatase

Gene

SPAC2F3.11

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Degradation of inorganic polyphosphates.By similarity

    Catalytic activityi

    (Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi40 – 401Manganese 1By similarity
    Metal bindingi42 – 421Manganese 2By similarity
    Metal bindingi116 – 1161Manganese 1By similarity
    Metal bindingi116 – 1161Manganese 2By similarity
    Metal bindingi138 – 1381Manganese 2By similarity
    Metal bindingi200 – 2001Manganese 2By similarity

    GO - Molecular functioni

    1. exopolyphosphatase activity Source: PomBase
    2. manganese ion binding Source: InterPro

    GO - Biological processi

    1. polyphosphate catabolic process Source: PomBase

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative exopolyphosphatase (EC:3.6.1.11)
    Short name:
    ExopolyPase
    Alternative name(s):
    Metaphosphatase
    Gene namesi
    ORF Names:SPAC2F3.11
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC2F3.11.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: PomBase
    2. cytosol Source: PomBase
    3. mitochondrial matrix Source: PomBase
    4. nucleus Source: PomBase
    5. plasma membrane Source: PomBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 384384Putative exopolyphosphatasePRO_0000158600Add
    BLAST

    Proteomic databases

    MaxQBiO14094.
    PaxDbiO14094.

    Interactioni

    Protein-protein interaction databases

    BioGridi278344. 43 interactions.
    MINTiMINT-4670429.
    STRINGi4896.SPAC2F3.11-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO14094.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPase class C family.Curated

    Phylogenomic databases

    eggNOGiCOG1227.
    KOiK01514.
    OMAiWILVDHN.
    OrthoDBiEOG7FNCH9.
    PhylomeDBiO14094.

    Family and domain databases

    InterProiIPR001667. DDH_dom.
    IPR004097. DHHA2.
    [Graphical view]
    PfamiPF01368. DHH. 1 hit.
    PF02833. DHHA2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O14094-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLGRFLENG REQIRNLLLN ASTVSSAPSF SFVSGNESAD LDSCASSIVY    50
    AYCLQRKQLG RIVVPFFNIP RKELRLRPEL SYLLNLASIS SDDIVFLDDI 100
    VKLPKRIFSN PIYLVDHNSL DRKDLENFNG SIAGIIDHHK DEGGSLHADP 150
    RIIEECGSCC TLVCRYFMPV IRSLYDSKVS ELHQTATNLA VLALGPILID 200
    TGNLKNEKTT DTDVKIVNDL CSFVPKDWVR DEFFDTLKEK KKSCKGFSFD 250
    DLLRRDLKQY FPDGIVVNYA SVGKGLDWIK KKRLGWEDEL KSFAEVQNSD 300
    LVIVGLSLSK NDEFGRQLIL YKRTERGAGL ADSFLKLSKQ NLGLEIIEEK 350
    DNGDLSMWNQ RNSAASRKKV VPLLMDSVKQ VASK 384
    Length:384
    Mass (Da):43,297
    Last modified:January 1, 1998 - v1
    Checksum:i643CC43C7AF185EA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16267.1.
    PIRiT38544.
    RefSeqiNP_594390.1. NM_001019812.2.

    Genome annotation databases

    EnsemblFungiiSPAC2F3.11.1; SPAC2F3.11.1:pep; SPAC2F3.11.
    GeneIDi2541853.
    KEGGispo:SPAC2F3.11.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB16267.1 .
    PIRi T38544.
    RefSeqi NP_594390.1. NM_001019812.2.

    3D structure databases

    ProteinModelPortali O14094.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 278344. 43 interactions.
    MINTi MINT-4670429.
    STRINGi 4896.SPAC2F3.11-1.

    Proteomic databases

    MaxQBi O14094.
    PaxDbi O14094.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC2F3.11.1 ; SPAC2F3.11.1:pep ; SPAC2F3.11 .
    GeneIDi 2541853.
    KEGGi spo:SPAC2F3.11.

    Organism-specific databases

    PomBasei SPAC2F3.11.

    Phylogenomic databases

    eggNOGi COG1227.
    KOi K01514.
    OMAi WILVDHN.
    OrthoDBi EOG7FNCH9.
    PhylomeDBi O14094.

    Miscellaneous databases

    NextBioi 20802941.
    PROi O14094.

    Family and domain databases

    InterProi IPR001667. DDH_dom.
    IPR004097. DHHA2.
    [Graphical view ]
    Pfami PF01368. DHH. 1 hit.
    PF02833. DHHA2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiPPX1_SCHPO
    AccessioniPrimary (citable) accession number: O14094
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 2005
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3