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Protein

DNA-directed RNA polymerase I subunit rpa49

Gene

rpa49

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase I subunit rpa49
Short name:
RNA polymerase I subunit A49
Alternative name(s):
DNA-directed RNA polymerase I 49 kDa polypeptide
Gene namesi
Name:rpa49
ORF Names:SPAC2F3.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC2F3.03c
PomBaseiSPAC2F3.03c rpa49

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

DNA-directed RNA polymerase, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000739541 – 425DNA-directed RNA polymerase I subunit rpa49Add BLAST425

Proteomic databases

MaxQBiO14086
PaxDbiO14086
PRIDEiO14086

PTM databases

iPTMnetiO14086

Interactioni

Subunit structurei

Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits.By similarity

Protein-protein interaction databases

BioGridi278404, 5 interactors
STRINGi4896.SPAC2F3.03c.1

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiO14086
KOiK03005
OMAiRRMNRVG
OrthoDBiEOG092C2DAL
PhylomeDBiO14086

Family and domain databases

InterProiView protein in InterPro
IPR009668 RNA_pol-assoc_fac_A49-like
PANTHERiPTHR14440 PTHR14440, 1 hit
PfamiView protein in Pfam
PF06870 RNA_pol_I_A49, 1 hit

Sequencei

Sequence statusi: Complete.

O14086-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGDELKGKK RKYRDSHSGD EKSVKILPLS ESSLPPLVTT ISGFYPPENT
60 70 80 90 100
RFQLLKKSNQ SNRDASLIGR TERVQFEAKN QSTATVEANY CLAVADKTGR
110 120 130 140 150
VKKIVPAKYL NTFERNILAL QEKDKFLKKK HGTVSGTVME QRANLGLAFG
160 170 180 190 200
TRKSQKAIME ESANRVKAET LGDVKDQLVS NVQKATEALP TQEDIAAAQA
210 220 230 240 250
QDRPIPPVNV GAESIEDAYK LEDIIPKEEF SAIYIKPLLE NPDERNWAKL
260 270 280 290 300
LPYRHSLFIN ERFQRLLSIE EVDQKRARIL YYISLLQAFL FSRRSVGNRE
310 320 330 340 350
TLRKKLADPP EILIDGLIKR FTQTTGIGSV QVSSREVDKI ICYILVLCLI
360 370 380 390 400
VDNYSTDVLT LANDLNVKTM KANELFRTVG CRIMAYTETQ RMALGLNKTD
410 420
AKNHKRAVLK IPLEFPKPRR GRARN
Length:425
Mass (Da):48,066
Last modified:January 1, 1998 - v1
Checksum:i1191EC48E6A75A76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ278613 mRNA Translation: CAC20964.1
CU329670 Genomic DNA Translation: CAB16261.1
PIRiT38536
RefSeqiNP_594382.1, NM_001019803.2

Genome annotation databases

EnsemblFungiiSPAC2F3.03c.1; SPAC2F3.03c.1:pep; SPAC2F3.03c
GeneIDi2541914
KEGGispo:SPAC2F3.03c

Similar proteinsi

Entry informationi

Entry nameiRPA49_SCHPO
AccessioniPrimary (citable) accession number: O14086
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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