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O14081 (TPSX_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit

EC=2.4.1.15
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene names
ORF Names:SPAC2E11.16c, SPACUNK4.16c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length944 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

Sequence similarities

In the N-terminal section; belongs to the glycosyltransferase 20 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 944944Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit
PRO_0000122512

Regions

Region173 – 652480Glycosyltransferase

Amino acid modifications

Modified residue1411Phosphoserine Ref.2
Modified residue1451Phosphoserine Ref.2
Modified residue1491Phosphoserine Ref.2
Modified residue1501Phosphoserine Ref.2
Modified residue1631Phosphoserine Ref.2
Modified residue1771Phosphoserine Ref.2
Modified residue1891Phosphothreonine Ref.2

Sequences

Sequence LengthMass (Da)Tools
O14081 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: D9B48874CCCB1A8A

FASTA944106,818
        10         20         30         40         50         60 
MGRILIAHLF LPSSVGFSFD TVPHDEVGSK FMQKEESKDW IADTPLDESA IVSEEESDDD 

        70         80         90        100        110        120 
SLLSDLPEEI DSTNAQSNIA TPSPGTVAAA ISGIQPPPKT PSSDSPSLEN SLSNLNDLFK 

       130        140        150        160        170        180 
SRGRHMAFSK NDGTNLSLPP SRHQSPPPSS VLASQRHHRR HDSELEEFAR RASRSLSFSM 

       190        200        210        220        230        240 
NGTPQRRMTF DAEAWKNVIF KIKPSSFGNA SFYNAISAAT RSKQFDDHLF VGTCGIPTDS 

       250        260        270        280        290        300 
LPDSLKERIS HDYITEHSSL VVYPTDTDFV GHYNHYCKNI LWPTFHYQIP DNPKSKAYED 

       310        320        330        340        350        360 
HSWANYVKVN KAFADTIVDN YEQDDMIWIN DYHLLLVPEM VRERLPRAKI GFFLHIPFPS 

       370        380        390        400        410        420 
SEVFRCLATR QEILKGMLGA NILGFQIPEF AYHFLQTCSR LVNIDIRKNG VVSFENRQID 

       430        440        450        460        470        480 
VIALPISIDP GFIDRCLASP PVEHWAKVLQ DRFRGKHIIL SHDKLDPIRG LRSKLISFER 

       490        500        510        520        530        540 
FLQKYPEYRE NTILLQVAPE SLQDSEHLPH ISDIVTRINS AYSNIASRHV PVILLRQKLG 

       550        560        570        580        590        600 
YAQFLALMMI SDALIDNSLR EGISLTSHQF IYVQRKRHRP LILSEFVGSA SILNDNAIIV 

       610        620        630        640        650        660 
NPWDYSKTAE AFRTALTMSE EECQKRNKAM CNLILRHDAA SWAVTFQSLI KESWKEQIDM 

       670        680        690        700        710        720 
QRIPAFTAQL IKEPYQNAQK RLILLYFEGT ISTWGSQYHN VMTSLQRTIN LLNMLTSDPK 

       730        740        750        760        770        780 
NTVYVFSALS CQELEQLFQR VPKLGIVAEN GCFVRSPPKG DATMPVSKKE IAELWKNKVL 

       790        800        810        820        830        840 
GTDLTWMKTV SEIFEYYAER TTGAYVENKD ATVILHLREA EDDEAAMWAA KECCESVNNF 

       850        860        870        880        890        900 
NVPCSATIQN DMVVCRSNKV SKRLAAEDIY SANGGDYDFI FAASNDPDDD TVFSWMKNFK 

       910        920        930        940 
QSKKEVVPFT FSVCVSEHGN STNADAESSG VFGFLQALEK VYSA 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-141; SER-145; SER-149; SER-150; SER-163; SER-177 AND THR-189, IDENTIFICATION BY MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAA20146.1.
PIRT41711.
RefSeqNP_593962.1. NM_001019389.2.

3D structure databases

ProteinModelPortalO14081.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278957. 12 interactions.
MINTMINT-4670308.
STRING4896.SPACUNK4.16c-1.

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Proteomic databases

PaxDbO14081.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPACUNK4.16c.1; SPACUNK4.16c.1:pep; SPACUNK4.16c.
GeneID2542498.
KEGGspo:SPACUNK4.16c.

Organism-specific databases

PomBaseSPACUNK4.16c.

Phylogenomic databases

eggNOGCOG0380.
HOGENOMHOG000179930.
KOK16055.
OMAINDSCES.
OrthoDBEOG76QFS6.
PhylomeDBO14081.

Family and domain databases

InterProIPR001830. Glyco_trans_20.
IPR023214. HAD-like_dom.
IPR003337. Trehalose_PPase.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
PF02358. Trehalose_PPase. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
ProtoNetSearch...

Other

NextBio20803552.

Entry information

Entry nameTPSX_SCHPO
AccessionPrimary (citable) accession number: O14081
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names