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O14081

- TPSX_SCHPO

UniProt

O14081 - TPSX_SCHPO

Protein

Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit

Gene

SPAC2E11.16c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

    GO - Molecular functioni

    1. alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Source: PomBase

    GO - Biological processi

    1. trehalose biosynthetic process Source: PomBase

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT20. Glycosyltransferase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunit (EC:2.4.1.15)
    Alternative name(s):
    Trehalose-6-phosphate synthase
    UDP-glucose-glucosephosphate glucosyltransferase
    Gene namesi
    ORF Names:SPAC2E11.16c, SPACUNK4.16c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPACUNK4.16c.

    Subcellular locationi

    GO - Cellular componenti

    1. alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) Source: PomBase
    2. cytosol Source: PomBase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 944944Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 106 kDa subunitPRO_0000122512Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei141 – 1411Phosphoserine1 Publication
    Modified residuei145 – 1451Phosphoserine1 Publication
    Modified residuei149 – 1491Phosphoserine1 Publication
    Modified residuei150 – 1501Phosphoserine1 Publication
    Modified residuei163 – 1631Phosphoserine1 Publication
    Modified residuei177 – 1771Phosphoserine1 Publication
    Modified residuei189 – 1891Phosphothreonine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiO14081.
    PaxDbiO14081.

    Interactioni

    Protein-protein interaction databases

    BioGridi278957. 12 interactions.
    MINTiMINT-4670308.
    STRINGi4896.SPACUNK4.16c-1.

    Structurei

    3D structure databases

    ProteinModelPortaliO14081.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni173 – 652480GlycosyltransferaseAdd
    BLAST

    Sequence similaritiesi

    In the N-terminal section; belongs to the glycosyltransferase 20 family.Curated

    Phylogenomic databases

    eggNOGiCOG0380.
    HOGENOMiHOG000179930.
    KOiK16055.
    OMAiANENECR.
    OrthoDBiEOG76QFS6.
    PhylomeDBiO14081.

    Family and domain databases

    InterProiIPR001830. Glyco_trans_20.
    IPR023214. HAD-like_dom.
    IPR003337. Trehalose_PPase.
    [Graphical view]
    PfamiPF00982. Glyco_transf_20. 1 hit.
    PF02358. Trehalose_PPase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O14081-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGRILIAHLF LPSSVGFSFD TVPHDEVGSK FMQKEESKDW IADTPLDESA    50
    IVSEEESDDD SLLSDLPEEI DSTNAQSNIA TPSPGTVAAA ISGIQPPPKT 100
    PSSDSPSLEN SLSNLNDLFK SRGRHMAFSK NDGTNLSLPP SRHQSPPPSS 150
    VLASQRHHRR HDSELEEFAR RASRSLSFSM NGTPQRRMTF DAEAWKNVIF 200
    KIKPSSFGNA SFYNAISAAT RSKQFDDHLF VGTCGIPTDS LPDSLKERIS 250
    HDYITEHSSL VVYPTDTDFV GHYNHYCKNI LWPTFHYQIP DNPKSKAYED 300
    HSWANYVKVN KAFADTIVDN YEQDDMIWIN DYHLLLVPEM VRERLPRAKI 350
    GFFLHIPFPS SEVFRCLATR QEILKGMLGA NILGFQIPEF AYHFLQTCSR 400
    LVNIDIRKNG VVSFENRQID VIALPISIDP GFIDRCLASP PVEHWAKVLQ 450
    DRFRGKHIIL SHDKLDPIRG LRSKLISFER FLQKYPEYRE NTILLQVAPE 500
    SLQDSEHLPH ISDIVTRINS AYSNIASRHV PVILLRQKLG YAQFLALMMI 550
    SDALIDNSLR EGISLTSHQF IYVQRKRHRP LILSEFVGSA SILNDNAIIV 600
    NPWDYSKTAE AFRTALTMSE EECQKRNKAM CNLILRHDAA SWAVTFQSLI 650
    KESWKEQIDM QRIPAFTAQL IKEPYQNAQK RLILLYFEGT ISTWGSQYHN 700
    VMTSLQRTIN LLNMLTSDPK NTVYVFSALS CQELEQLFQR VPKLGIVAEN 750
    GCFVRSPPKG DATMPVSKKE IAELWKNKVL GTDLTWMKTV SEIFEYYAER 800
    TTGAYVENKD ATVILHLREA EDDEAAMWAA KECCESVNNF NVPCSATIQN 850
    DMVVCRSNKV SKRLAAEDIY SANGGDYDFI FAASNDPDDD TVFSWMKNFK 900
    QSKKEVVPFT FSVCVSEHGN STNADAESSG VFGFLQALEK VYSA 944
    Length:944
    Mass (Da):106,818
    Last modified:January 1, 1998 - v1
    Checksum:iD9B48874CCCB1A8A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAA20146.1.
    PIRiT41711.
    RefSeqiNP_593962.1. NM_001019389.2.

    Genome annotation databases

    EnsemblFungiiSPACUNK4.16c.1; SPACUNK4.16c.1:pep; SPACUNK4.16c.
    GeneIDi2542498.
    KEGGispo:SPACUNK4.16c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAA20146.1 .
    PIRi T41711.
    RefSeqi NP_593962.1. NM_001019389.2.

    3D structure databases

    ProteinModelPortali O14081.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 278957. 12 interactions.
    MINTi MINT-4670308.
    STRINGi 4896.SPACUNK4.16c-1.

    Protein family/group databases

    CAZyi GT20. Glycosyltransferase Family 20.

    Proteomic databases

    MaxQBi O14081.
    PaxDbi O14081.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPACUNK4.16c.1 ; SPACUNK4.16c.1:pep ; SPACUNK4.16c .
    GeneIDi 2542498.
    KEGGi spo:SPACUNK4.16c.

    Organism-specific databases

    PomBasei SPACUNK4.16c.

    Phylogenomic databases

    eggNOGi COG0380.
    HOGENOMi HOG000179930.
    KOi K16055.
    OMAi ANENECR.
    OrthoDBi EOG76QFS6.
    PhylomeDBi O14081.

    Miscellaneous databases

    NextBioi 20803552.

    Family and domain databases

    InterProi IPR001830. Glyco_trans_20.
    IPR023214. HAD-like_dom.
    IPR003337. Trehalose_PPase.
    [Graphical view ]
    Pfami PF00982. Glyco_transf_20. 1 hit.
    PF02358. Trehalose_PPase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    2. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-141; SER-145; SER-149; SER-150; SER-163; SER-177 AND THR-189, IDENTIFICATION BY MASS SPECTROMETRY.

    Entry informationi

    Entry nameiTPSX_SCHPO
    AccessioniPrimary (citable) accession number: O14081
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 2002
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3