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O14022 (ATCY_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cation-transporting ATPase C29A4.19c
EC=3.6.3.-
Gene names
ORF Names:SPAC29A4.19c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length1096 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + H2O = ADP + phosphate.

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10961096Probable cation-transporting ATPase C29A4.19c
PRO_0000046353

Regions

Topological domain1 – 1919Cytoplasmic Potential
Transmembrane20 – 4122Helical; Potential
Topological domain42 – 476Extracellular Potential
Transmembrane48 – 7023Helical; Potential
Topological domain71 – 193123Cytoplasmic Potential
Transmembrane194 – 21623Helical; Potential
Topological domain217 – 2204Extracellular Potential
Transmembrane221 – 23818Helical; Potential
Topological domain239 – 391153Cytoplasmic Potential
Transmembrane392 – 41221Helical; Potential
Topological domain413 – 42513Extracellular Potential
Transmembrane426 – 44722Helical; Potential
Topological domain448 – 895448Cytoplasmic Potential
Transmembrane896 – 91520Helical; Potential
Topological domain916 – 9227Extracellular Potential
Transmembrane923 – 94018Helical; Potential
Topological domain941 – 95818Cytoplasmic Potential
Transmembrane959 – 98224Helical; Potential
Topological domain983 – 100321Extracellular Potential
Transmembrane1004 – 102623Helical; Potential
Topological domain1027 – 104014Cytoplasmic Potential
Transmembrane1041 – 106020Helical; Potential
Topological domain1061 – 107515Extracellular Potential
Transmembrane1076 – 109621Helical; Potential

Sites

Active site48014-aspartylphosphate intermediate By similarity
Metal binding8381Magnesium By similarity
Metal binding8421Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
O14022 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 44BF98911481A543

FASTA1,096121,936
        10         20         30         40         50         60 
MDSIELKQLV PENDSEPGTP RQLLFQHYDI SNEETIGIKP FKSIPAKVYI LRVTEILTLG 

        70         80         90        100        110        120 
LLHLILTWLP EFRLKWIEAP CSNEDVEFVA ISDPSGTSSI EKVSSICLKN DIQTSSFVLP 

       130        140        150        160        170        180 
SGKTRYFEYK KLRFYLEPLN LQWVLMPLET SAYSLVTSTP AYIQNGLDTF TIAKLRQVYG 

       190        200        210        220        230        240 
SNSLVSTKKS IVTILLNEVL HPFYLFQAVS VLIWLCDSFV FYSCCIVFIS SYSIFLSVKE 

       250        260        270        280        290        300 
SKESENRIHS IIGAPQPVTV IRNQVKQTVL ADDLVIGDLL YFSNLDLKTC PVDGILFSSS 

       310        320        330        340        350        360 
CLLDESMVTG ESVPARKFPL EDNSLDSWMI ASCNIFSPHL IHAGTKFLKI DSTPSTPCLI 

       370        380        390        400        410        420 
SVVRTGFRSN KGQLIRNLLY PNLRPSQLYL DSMSFLKTMA ILSFVSIVFI AIYLNLYNAS 

       430        440        450        460        470        480 
FGHVVLRSLD VLTILVPPAL PATLSVGIAN SIARLSRALI YTTSPESIHN AGCLSTFVFD 

       490        500        510        520        530        540 
KTGTLTENSV QLSCVYVKSG SNGLLKQVDA DSLSLDSTKL NAHAYRVATC SQSLELVGNE 

       550        560        570        580        590        600 
LVGDPLEVTL FTQFNGTFCA TIRASNTPHP PLFSVSNSFD GPSQIFSIYK ALEFDPVLRR 

       610        620        630        640        650        660 
MSVICSTSTE RSLMLFTKGA PESILAISSQ QSIPSNVQEV IHTLSSKGFR IIAFASKNLI 

       670        680        690        700        710        720 
TPLQELIHLS RSTLESNVTF QGLFVLESPL RESSKDVISS LLRSKMEVSI CSGDSLFTSV 

       730        740        750        760        770        780 
FVAKHCGALD SCNFIYTAEL ADSGDDCPQI HFEKIDLQTQ NFQPIPDGFS LKDVILEKDS 

       790        800        810        820        830        840 
SLCMDGKLLQ RLLTMLSFNE IKILLSKLRV LARMSPFDKA TYVELCQKYG CKVGFCGDGA 

       850        860        870        880        890        900 
NDCIALKQAD VGVSLSDSEA CAAASFVSKK KSIKDVFNVL LEGRCSLILS HRCFQYMVLC 

       910        920        930        940        950        960 
AIVQFSGVFF LYLKNYNFND NQFLFMDLLI IFPLSAAMSY FDPAQNLTSN RPNSTLFGKG 

       970        980        990       1000       1010       1020 
RVKDLGIQSV LIWLSHGLLT LILHELNWVE LPEWQLEKSN TKNVLVTSIF LLSSLQYLGI 

      1030       1040       1050       1060       1070       1080 
CIGINQSSEF LSPIWKKKTY VCLCTTIGLC NIYLCFANEN HIISRCLQIT RLPTLYRFII 

      1090 
LFMGVISCCL TSILNM

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329670 Genomic DNA. Translation: CAB10145.1.
PIRT38470.
RefSeqNP_594863.1. NM_001020292.1.

3D structure databases

ProteinModelPortalO14022.
ModBaseSearch...

Protein family/group databases

TCDB3.A.3.17.1. P-type ATPase (P-ATPase) superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC29A4.19c.1; SPAC29A4.19c.1:pep; SPAC29A4.19c.
GeneID2542076.
KEGGspo:SPAC29A4.19c.
NMPDRfig|4896.1.peg.4833.

Organism-specific databases

GeneDB_SpombeSPAC29A4.19c.

Phylogenomic databases

eggNOGfuNOG05761.
GeneTreeEFGT00050000000742.
OrthoDBEOG4BK8DV.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-002932-MONOMER.

Gene expression databases

ArrayExpressO14022.

Family and domain databases

InterProIPR023306. ATPase_cation_domN.
IPR008250. ATPase_P-typ_ATPase-assoc-dom.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023300. ATPase_P-typ_cyto_domA.
IPR023299. ATPase_P-typ_cyto_domN.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_P_site.
IPR006544. ATPase_P-typ_unknown-pump-sp.
IPR023214. HAD-like_dom.
IPR000150. Hypothet_cof.
[Graphical view]
Gene3DG3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit.
G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit.
G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KOK14951.
PfamPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
SUPFAMSSF81660. ATPase_cation_domN. 1 hit.
SSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01494. ATPase_P-type. 2 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATCY_SCHPO
AccessionPrimary (citable) accession number: O14022
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: December 14, 2011
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents