Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucan 1,3-beta-glucosidase

Gene

bgl2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.

Catalytic activityi

Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei244NucleophileBy similarity1
Active sitei300Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiGH17 Glycoside Hydrolase Family 17

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan 1,3-beta-glucosidase (EC:3.2.1.58)
Alternative name(s):
Exo-1,3-beta-glucanase
Gene namesi
Name:bgl2
ORF Names:SPAC26H5.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC26H5.08c
PomBaseiSPAC26H5.08c bgl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000001189522 – 321Glucan 1,3-beta-glucosidaseAdd BLAST300

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi39N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi99N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi210N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi213N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi237N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi309N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi317N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiO13990
PaxDbiO13990
PRIDEiO13990

Interactioni

Protein-protein interaction databases

BioGridi27915320 interactors.
STRINGi4896.SPAC26H5.08c.1

Structurei

3D structure databases

ProteinModelPortaliO13990
SMRiO13990
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000207150
InParanoidiO13990
KOiK01210
OMAiWKPDTSG
OrthoDBiEOG092C3V78
PhylomeDBiO13990

Family and domain databases

InterProiView protein in InterPro
IPR000490 Glyco_hydro_17
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00332 Glyco_hydro_17, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00587 GLYCOSYL_HYDROL_F17, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O13990-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFLSSFVFA ALALLPLSAM AVDEAASEIA SSTKPASTNG TLSFCLGVKH
60 70 80 90 100
ADGTCKYTDD YLADFEVLAP YTNMIRTYAT SDCNTLEYLL PALAQSPYNF
110 120 130 140 150
SAILGVWPTD DAHYDLEKQA LMQYLPQYGV DHVRAITVGS EVLYRNDLPA
160 170 180 190 200
DVLAERIYDV RGLVQQKLGF DVPVGTADSW NLWAGGSGDV VITASDFIMS
210 220 230 240 250
NDFPYWQGQN TSNMTNTFIS DTLAALERVQ SVKGTNNVTF WVGETGWPTD
260 270 280 290 300
GPSYGEADAT VDIASEFFQE ALCNIRRKGI DIFFFEAFDE DWKGDSSSVE
310 320
PYFGAMYSNR TLKYNLNCTS E
Length:321
Mass (Da):35,412
Last modified:February 1, 2005 - v4
Checksum:i10094466592006CA
GO

Sequence cautioni

The sequence BAA19145 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti281D → N in BAA19145 (PubMed:9501991).Curated1
Sequence conflicti303F → L in BAA19145 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16200.1
AB000539 mRNA Translation: BAA19145.1 Different initiation.
PIRiT38427
RefSeqiNP_594455.1, NM_001019884.2

Genome annotation databases

EnsemblFungiiSPAC26H5.08c.1; SPAC26H5.08c.1:pep; SPAC26H5.08c
GeneIDi2542700
KEGGispo:SPAC26H5.08c

Similar proteinsi

Entry informationi

Entry nameiBGL2_SCHPO
AccessioniPrimary (citable) accession number: O13990
Secondary accession number(s): P79062
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: April 25, 2018
This is version 107 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome