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Protein

ATPase WRNIP1 homolog C26H5.02c

Gene

SPAC26H5.02c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri6 – 29UBZ-typeAdd BLAST24
Nucleotide bindingi127 – 134ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

DNA damage, DNA replication

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
ATPase WRNIP1 homolog C26H5.02c
Gene namesi
ORF Names:SPAC26H5.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC26H5.02c.
PomBaseiSPAC26H5.02c.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003102801 – 504ATPase WRNIP1 homolog C26H5.02cAdd BLAST504

Proteomic databases

MaxQBiO13984.
PRIDEiO13984.

Interactioni

Protein-protein interaction databases

BioGridi278572. 23 interactors.

Structurei

3D structure databases

ProteinModelPortaliO13984.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 UBZ-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri6 – 29UBZ-typeAdd BLAST24

Keywords - Domaini

Zinc-finger

Phylogenomic databases

HOGENOMiHOG000017623.
InParanoidiO13984.
KOiK07478.
OMAiYRYDHDE.
OrthoDBiEOG092C1X6E.
PhylomeDBiO13984.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR032423. AAA_assoc_2.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR021886. MgsA_C.
IPR027417. P-loop_NTPase.
IPR006642. Znf_Rad18_put.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF16193. AAA_assoc_2. 1 hit.
PF12002. MgsA_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00734. ZnF_Rad18. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

O13984-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGPDHVQCP VCAKTVTMND INPHLDSHYS DSSGPSKPVS PFFKKERYKH
60 70 80 90 100
HLETNVSSHQ SATKFIEPEP SPTKKTKLTR RDTRPLAERA RPKSLDEYVG
110 120 130 140 150
QEELVGERGI IRNLIEQDRC NSMILWGSAG TGKTTLARLI AVTTKSRFIE
160 170 180 190 200
ISATSTTVAD CRKIFEDSQN YLTLTGRKTI IFLDEVHRFN RAQQDIFLPM
210 220 230 240 250
VEKGLVTLIG ATTENPSFRL NSALISRCPV FVLKKLTRDN VKKILNHACL
260 270 280 290 300
LESERLGSSM PNVETSIIDY ISAITDGDAR MALNALEMSI GMLRQGPLSL
310 320 330 340 350
EDIKDKLVRS SALYDRVGDV HYDTISAFHK SVRGSDVDAT LYYLGRMLES
360 370 380 390 400
GEDPLYVARR MVRIASEDIG IADNSMLPLA SSTFTAVQQV GMPEADVILA
410 420 430 440 450
HCAVALALAP KSVDVYRSYN AVKSFLSSHP DAGRAEIPMH IRNAPTNLMK
460 470 480 490 500
QLGYHKGYKY NPDYKDGLVM QEYLPDSIKG TKFYKLPIEL KEDEEIKNLK

TDTK
Length:504
Mass (Da):56,306
Last modified:May 24, 2005 - v2
Checksum:i4DA6DA297723D90A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16188.2.
PIRiT38421.
RefSeqiNP_594449.2. NM_001019878.3.

Genome annotation databases

EnsemblFungiiSPAC26H5.02c.1; SPAC26H5.02c.1:pep; SPAC26H5.02c.
GeneIDi2542096.
KEGGispo:SPAC26H5.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16188.2.
PIRiT38421.
RefSeqiNP_594449.2. NM_001019878.3.

3D structure databases

ProteinModelPortaliO13984.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278572. 23 interactors.

Proteomic databases

MaxQBiO13984.
PRIDEiO13984.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC26H5.02c.1; SPAC26H5.02c.1:pep; SPAC26H5.02c.
GeneIDi2542096.
KEGGispo:SPAC26H5.02c.

Organism-specific databases

EuPathDBiFungiDB:SPAC26H5.02c.
PomBaseiSPAC26H5.02c.

Phylogenomic databases

HOGENOMiHOG000017623.
InParanoidiO13984.
KOiK07478.
OMAiYRYDHDE.
OrthoDBiEOG092C1X6E.
PhylomeDBiO13984.

Miscellaneous databases

PROiO13984.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR032423. AAA_assoc_2.
IPR003959. ATPase_AAA_core.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR021886. MgsA_C.
IPR027417. P-loop_NTPase.
IPR006642. Znf_Rad18_put.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF16193. AAA_assoc_2. 1 hit.
PF12002. MgsA_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00734. ZnF_Rad18. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiWRIP1_SCHPO
AccessioniPrimary (citable) accession number: O13984
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.