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Protein

Oxysterol-binding protein homolog C23H4.01c

Gene

SPAC23H4.01c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Enzyme and pathway databases

ReactomeiR-SPO-192105 Synthesis of bile acids and bile salts

Names & Taxonomyi

Protein namesi
Recommended name:
Oxysterol-binding protein homolog C23H4.01c
Gene namesi
ORF Names:SPAC23H4.01c, SPAP27G11.01
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23H4.01c
PomBaseiSPAC23H4.01c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001003921 – 945Oxysterol-binding protein homolog C23H4.01cAdd BLAST945

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei288Phosphoserine1 Publication1
Modified residuei419Phosphoserine1 Publication1
Modified residuei421Phosphoserine1 Publication1
Modified residuei503Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO13944
PaxDbiO13944
PRIDEiO13944

PTM databases

iPTMnetiO13944

Interactioni

Protein-protein interaction databases

STRINGi4896.SPAC23H4.01c.1

Structurei

3D structure databases

ProteinModelPortaliO13944
SMRiO13944
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 131GOLDPROSITE-ProRule annotationAdd BLAST131
Domaini149 – 243PHPROSITE-ProRule annotationAdd BLAST95

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi362 – 475Ser-richAdd BLAST114

Sequence similaritiesi

Belongs to the OSBP family.Curated

Phylogenomic databases

HOGENOMiHOG000193697
InParanoidiO13944
KOiK20463
OMAiGKCEADK
OrthoDBiEOG092C0T4H
PhylomeDBiO13944

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR009038 GOLD_dom
IPR036598 GOLD_dom_sf
IPR037239 OSBP_sf
IPR000648 Oxysterol-bd
IPR018494 Oxysterol-bd_CS
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR10972 PTHR10972, 1 hit
PfamiView protein in Pfam
PF01237 Oxysterol_BP, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF101576 SSF101576, 2 hits
SSF144000 SSF144000, 1 hit
PROSITEiView protein in PROSITE
PS50866 GOLD, 1 hit
PS01013 OSBP, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

O13944-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METVEIRSKS LLIQWLTVES NSLLSWQLHV KRKSIKFDIY HKKNDTSSLL
60 70 80 90 100
DGSNKNTDRS ILHTKRQHTH EAGIKKLSAA GLELFYQGER CMSEKPSEGS
110 120 130 140 150
VYIENGGLYA FVFDNTFSKT KPKTVTFLLT AQPYNGPRIP NASVHGSPKQ
160 170 180 190 200
IISGTLLKKR RKKGQGYARR YFTLNMVEGT ISYYANENSS VMRGKIPLSI
210 220 230 240 250
AVISVAAETH EINVDSGVEL WNLRAHTHQD WLRWCNALEK AKNSQTSSKL
260 270 280 290 300
VVDERTQESS SNQLVSIYSR LRECLDIAQL YRTSRIKSAS SHNFSVPEIR
310 320 330 340 350
IQLPGDAKEN KETRTSVEIT AAENAQAAVT LRKVTRQLGS LLHELECFIQ
360 370 380 390 400
HHEYTKERTA QSSPSSRMSM DSNFEQHWYD AEDYESTTSQ LNHYSESGAH
410 420 430 440 450
AADATKSSVA HNEKVEDISD SDIPIMKTSS NSTSLDADRD SDTSSISDTS
460 470 480 490 500
SNSSAPHEQL NATSLASTVD ESSRSPPLPE VESNKENDIK RKQPFHDLMD
510 520 530 540 550
SSSPDDSSFA NAKSDEEVQK PSVSKNIADG AVISIPKPLT PKPSDSNSLY
560 570 580 590 600
PLPHSKVGRR KNIPAITVPP PSILSILRKN IGKDISSIPA PVVSNEPCNL
610 620 630 640 650
LQRCAEDLEY SNMLDKANEC DDDIKIFYVA AFAVSNFSNM RHKERSVRKV
660 670 680 690 700
FSPLLGETFE LVREDRNYRF LAEKVCHRPL IIACHAESRN WIWNHSPKPI
710 720 730 740 750
QKFWGKSVEL NTLGPVTIKL ACGTEFSFMK PACFLKNVAI GEKYVEPYDH
760 770 780 790 800
MEIVDETTGD KAVIRFKSGG MFSGRSEDVL VTVIRSNGEE DPKCLQGKWT
810 820 830 840 850
SHLDFVNTDE GNVIERIWEV GPLVDKPEDH CGMTVFAAQM NEITDLEKDK
860 870 880 890 900
LPPTDTRLRP DQRYRENNDL DHAEPLKLEL EQKQRERRKE MEEKDIKWEP
910 920 930 940
RWFVPSVAGD DEDEDGSGPI WQLKKENNYW ESRENSTWSS CPKLW
Length:945
Mass (Da):106,810
Last modified:December 13, 2002 - v2
Checksum:iB8E264181310A4BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB11656.1
AB028015 Genomic DNA Translation: BAA87319.1
RefSeqiNP_593405.2, NM_001018838.2

Genome annotation databases

EnsemblFungiiSPAC23H4.01c.1; SPAC23H4.01c.1:pep; SPAC23H4.01c
GeneIDi2541796
KEGGispo:SPAC23H4.01c

Similar proteinsi

Entry informationi

Entry nameiYEH1_SCHPO
AccessioniPrimary (citable) accession number: O13944
Secondary accession number(s): Q9P7N7, Q9US66
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2002
Last sequence update: December 13, 2002
Last modified: April 25, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health